Neuroprotective Effects of Food Ingredients
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 1621
Special Issue Editors
Interests: biorefinery; green processes; sustainable processes; plants; algae; agricultural by-products; chemical characterization
Special Issues, Collections and Topics in MDPI journals
Interests: foodomics; metabolomics; molecular mechanisms; neuroprotection; sustainable biomass; advanced chemical characterization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative disorders, such as Parkinson’s and Alzheimer’s disease, are a group of diseases characterized by the progressive loss of neurons from different regions of the brain, causing progressive cognitive impairment, mental deterioration and degeneration of brain tissue. Neurodegenerative disorders share some molecular and cellular characteristics, such as a multifactorial character, related to oxidative stress and free radical formation, neuroinflammation, mitochondrial dysfunction, etc. Presently, there are no therapeutic approaches to cure or even halt the progression of these disorders. On the other hand, external factors related to lifestyle, such as diet, have been postulated as preventive factors in neurodegeneration; in this regard, bioactive food ingredients, such as terpenoids, lipids, phenolic compounds, carotenoids, polysaccharides, peptides, etc., may interfere with different molecular mechanisms related to the progression of such diseases, considering their important associated biological activities. Although huge efforts have been focused on finding new possible therapeutics’ treatments, there is still a long way to go before we completely understand the molecular action of dietary compounds or food ingredients in the prevention of neurodegenerative disorders.
In this Special Issue, we invite researchers to contribute original research articles, as well as review articles, regarding the biological effect of food ingredients and bioactives from agri-food by-products in the prevention of neurodegeneration.
Topics include, but are not limited to, the following:
- Studies (in vitro, in vivo, animal, pre-clinical, clinical) regarding the effect of food ingredients and bioactive compounds from agri-food by-products in the treatment of neurodegenerative diseases;
- The role of food ingredients and bioactive compounds from agri-food by-products against oxidative stress in neurodegeneration;
- The role of food ingredients and bioactive compounds from agri-food by-products against inflammation in neurodegeneration;
- The development of new food ingredients targeting multifactorial neurodegeneration;
- Transformation of food ingredients during digestion and its effects on counteracting neurodegeneration;
- New mechanisms of food ingredients and bioactive compounds from agri-food by-products in crossing the blood–brain barrier (BBB);
- Omics approaches including foodomics for neuroprotection studies.
Prof. Dr. Elena Ibáñez
Prof. Dr. Alejandro Cifuentes
Guest Editors
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Keywords
- neuroprotection
- Parkinson
- Alzheimer
- bioactive compounds
- agri-food by-products
- chemical characterization
- foodomics
- metabolomics
- molecular mechanisms
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