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Urologic Surgery: From Bench to Bedside
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Urologic Surgery: From Bench to Bedside

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 6 May 2025 | Viewed by 2266

Special Issue Editor

Prof. Dr. Riccardo Lombardo

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Guest Editor
Department of Urology, Sapienza Università di Roma, Via di Grottarossa, 00189 Rome, Italy
Interests: minimally invasive surgery in urologic oncology and benign urological diseases; robotic; minimally Invasive; partial nephrectomy; focal therapy; iTind; Urolift; Rezum; aquablation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are glad to announce this Special Issue of the Journal of Clinical Medicine, entitled ‘Urologic Surgery: From Bench to Bedside’. This Special Issue focuses on the dynamic and rapidly evolving field of urologic surgery, highlighting the journey of scientific innovations from basic research to clinical application.

In recent years, the field of urology has witnessed significant advancements, driven by groundbreaking research and technological innovations. This Special Issue aims to bridge the gap between laboratory research (the ‘bench’) and patient care (the ‘bedside’), showcasing the latest developments in surgical techniques, patient management, and treatment modalities in urologic surgery. Featuring a collection of peer-reviewed articles, this Special Issue welcomes contributions from leading experts in urology, surgery, oncology, and biomedical engineering. We aim to cover a wide range of topics, from minimally invasive surgical techniques and robotic-assisted procedures to the development of new diagnostic tools and treatment strategies for urological diseases, such as prostate cancer, bladder disorders, benign prostatic hyperplasia, and kidney diseases.

Our goal is to provide a comprehensive overview of the current trends and future directions in urologic surgery, offering valuable insights for clinicians, surgeons, researchers, and healthcare professionals. This Special Issue not only highlights the importance of translational research in improving patient outcomes but also underscores the collaboration needed across various disciplines to advance the field of urologic surgery.

Join us in exploring the exciting and challenging journey of urologic surgery in this Special Issue, from bench to bedside.

Prof. Dr. Riccardo Lombardo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • minimally invasive
  • robotics
  • partial nephrectomy
  • radical prostatectomy
  • focal therapy
  • benign prostatic hyperplasia
  • iTind
  • Urolift
  • Rezum
  • aquablation
  • enucleation

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Published Papers (2 papers)

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Research

7 pages, 421 KiB  
Article
Multiparametric Prostate MRI Accuracy of Prostate Imaging Reporting and Data System (v2.1) Scores 4 and 5: The Influence of Image Quality According to the Prostate Imaging Quality Score
by Andrea Fuschi, Paolo Pietro Suraci, Antonio Luigi Pastore, Yazan Al Salhi, Paola Capodiferro, Silvio Scalzo, Onofrio Antonio Rera, Fabio Maria Valenzi, Michele Di Dio, Pierluigi Russo, Mohammad Talal Al-Zubi, Saddam Al Demour, Samer Fathi Al-Rawashdah, Giorgio Mazzon, Davide Bellini, Iacopo Carbone, Vincenzo Petrozza, Giorgio Bozzini, Alessandro Zucchi, Matteo Pacini, Giorgia Tema, Cosimo De Nunzio, Antonio Carbone and Marco Rengoadd Show full author list remove Hide full author list
J. Clin. Med. 2024, 13(13), 3785; https://doi.org/10.3390/jcm13133785 - 27 Jun 2024
Viewed by 873
Abstract
Purpose: The accuracy of multiparametric magnetic resonance imaging (mpMRI) heavily relies on image quality, as evidenced by the evolution of the prostate imaging quality (PI-QUAL) scoring system for the evaluation of clinically significant prostate cancer (csPC). This study aims to evaluate the impact [...] Read more.
Purpose: The accuracy of multiparametric magnetic resonance imaging (mpMRI) heavily relies on image quality, as evidenced by the evolution of the prostate imaging quality (PI-QUAL) scoring system for the evaluation of clinically significant prostate cancer (csPC). This study aims to evaluate the impact of PI-QUAL scores in detecting csPC within PI-RADS 4 and 5 lesions. Methods: We retrospectively selected from our database all mpMRI performed from January 2019 to March 2022. Inclusion criteria were as follows: (1) mpMRI acquired in our institution according to the technical requirements from the PI-RADS (v2.1) guidelines; (2) single lesion scored as PI-RADS (v2.1) 4 or 5; (3) MRI-TBx performed in our institution; (4) complete histology report; and (5) complete clinical record. Results: A total of 257 male patients, mean age 70.42 ± 7.6 years, with a single PI-RADS 4 or 5 lesion undergoing MRI-targeted biopsy, were retrospectively studied. Of these, 61.5% were PI-RADS 4, and 38.5% were PI-RADS 5, with 84% confirming neoplastic cells. In high-quality image lesions (PI-QUAL ≥ 4), all PI-RADS 5 lesions were accurately identified as positive at the final histological examination (100% of CDR). For PI-RADS 4 lesions, 37 (23%) were negative, resulting in a cancer detection rate of 77% (95% CI: 67.51–84.83). Conclusions: The accuracy of mpMRI, independently of the PI-RADS score, progressively decreased according to the decreasing PI-QUAL score. These findings emphasize the crucial role of the PI-QUAL scoring system in evaluating PI-RADS 4 and 5 lesions, influencing mpMRI accuracy. Full article
(This article belongs to the Special Issue Urologic Surgery: From Bench to Bedside)
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9 pages, 4530 KiB  
Article
Purely Off-Clamp Sutureless Robotic Partial Nephrectomy for Novice Robotic Surgeons: A Multi-Institutional Propensity Score-Matched Analysis
by Cosimo De Nunzio, Giorgia Tema, Aldo Brassetti, Umberto Anceschi, Alfredo Maria Bove, Simone D’Annunzio, Mariaconsiglia Ferriero, Riccardo Mastroianni, Leonardo Misuraca, Salvatore Guaglianone, Gabriele Tuderti, Costantino Leonardo, Riccardo Lombardo, Antonio Cicione, Antonio Franco, Eugenio Bologna, Leslie Claire Licari, Sara Riolo, Rocco Simone Flammia, Antonio Nacchia, Alberto Trucchi, Giorgio Franco, Andrea Tubaro and Giuseppe Simoneadd Show full author list remove Hide full author list
J. Clin. Med. 2024, 13(12), 3553; https://doi.org/10.3390/jcm13123553 - 18 Jun 2024
Cited by 2 | Viewed by 1032
Abstract
Objectives: To compare perioperative outcomes of patients treated with sutureless off-clamp robotic partial nephrectomy (sl-oc RAPN) by either a novice or an expert robotic surgeon at two different institutions. Methods: Data concerning two continuous series of patients with cT1-2N0M0 renal tumors treated with [...] Read more.
Objectives: To compare perioperative outcomes of patients treated with sutureless off-clamp robotic partial nephrectomy (sl-oc RAPN) by either a novice or an expert robotic surgeon at two different institutions. Methods: Data concerning two continuous series of patients with cT1-2N0M0 renal tumors treated with sl-oc RAPN either by a novice or an expert surgeon were extracted from prospectively populated institutional databases over the last 4 years. Perioperative outcomes as well as the baseline characteristics of patients and tumors were compared by using χ2 and Mann–Whitney tests for categorical and continuous variables, respectively. A 1:1 propensity match score analysis (PMSa) generated two homogeneous cohorts. Logistic regression analysis was performed to assess predictors of trifecta outcomes, defined as negative surgical margins, no Clavien–Dindo ≧ 3 grade complications, and no ≧ 30% postoperative eGFR reduction. Results: Overall, 328 patients were treated by an expert surgeon, while 40 were treated by a novice surgeon. After PMSa analysis, two cohorts of 23 patients each were generated, homogeneous for all baseline variables (p ≥ 0.07). Hospital stay was the only significantly different outcome observed between the two groups (5 days vs. 2 days; p < 0.001). No statistically significant differences were recorded when comparing trifecta outcomes (expert: 100% vs. novice: 87%; p = 0.07). In the logistic regression analysis, no statistically significant predictors of trifecta outcomes were recorded. Conclusions: sl-oc RAPN is a feasible and safe nephron sparing technique, even when performed by a novice robotic surgeon. Full article
(This article belongs to the Special Issue Urologic Surgery: From Bench to Bedside)
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