Recent Advance in the Management of Morphea
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dermatology".
Deadline for manuscript submissions: closed (15 December 2021) | Viewed by 12674
Special Issue Editors
Interests: psoriasis and comorbidities; atopic dermatitis; morphea; systemic sclerosis; skin cancers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Morphea (localized scleroderma, LoSc) and Lichen sclerosus (LS) are rare autoimmune-induced inflammatory and sclerotic skin diseases that may have similar clinical appearance. LoS often involves underlying tissues while LS is a mucocutaneous disorder of genital and extragenital skin, causing itch, pain, dysuria, dyspareunia, and significant sexual dysfunction in women and men with potential progression to squamous cell carcinoma (SCC). The etiopathogenesis is not fully understood, but it is assumed that some genetic, epigenetic and environmental factors are involved. Morphea is more common in the Caucasian population, and in females, with a female to male ratio of 4:2, and children with morphea representing approximately 15% that of the adult morphea population. The exact prevalence of LS is about 0.1–0.3 % but it is probably underestimated. Both adult female and male patients are affected, and it occurs in prepubertal children. The treatment management depends on the activity/severity and clinical type of the disease as well as the patient’s age and should be introduced according to guidelines. Despite the use of a recommended therapy, either morphea or LS are relapsing disease with a potential for atrophy, disfigurement and functional impairment. This Special Issue invites articles concerning recent advances in the management of morphea, drawing on both experimental and clinical data related to the disease. We would appreciate the novelty of the manuscript.
In summary, I am happy to be the guest editor of this issue and welcome your Special Issue submissions, hoping your contributions make its success.
Prof. Dr. Dorota Krasowska
Dr. Małgorzata Michalska-Jakubus
Guest Editors
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Keywords
- Morphea
- Lichen sclerosus
- Etiopathogenesis
- Antibodies
- Treatment
- Cosmetic treatment
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