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Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea...
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Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Pulmonology".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 1302

Special Issue Editor

Dr. Pierluigi Carratù

E-Mail Website
Guest Editor
Institute of Internal Medicine “A. Murri”, Department of Precision and Regenerative Medicine and Ionian Area, Università Degli Studi di Bari Aldo Moro, Bari, Italy
Interests: obstructive sleep apnea (OSA); respiratory diseases; COPD; noninvasive ventilation; pulmonary fibrosis; lung function; smoking; pollution
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

With the success of our first Special Issue, entitled “Obstructive Sleep Apnea (OSA): What Can We Do Now?” (https://www.mdpi.com/si/jcm/8A543T08PX), we are launching a new Special Issue, entitled “Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)”, continuing to report on clinical research.

Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder characterized by the collapse of the pharynx during sleep, as well as recurrent episodes of upper airway obstruction during sleep, leading to intermittent hypoxia and sleep fragmentation. Partial arousals frequently occur throughout sleep, resulting in relative sleep deprivation and daytime fatigue. If left untreated, OSAS can have significant adverse effects on an individual's health and quality of life. Therefore, it has been increasingly recognized as a major health issue.

For this Special Issue, entitled “Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)”, we continue to welcome contributions on the topic of OSAS. We invite original research papers based on original data, as well as review articles. All manuscripts will be subjected to a standard peer review process, in line with the journal’s procedures and policies.

Dr. Pierluigi Carratù
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obstructive sleep apnea syndrome
  • diagnosis
  • obesity
  • treatment
  • CPAP
  • comorbidities
  • cardiovascular risk

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Published Papers (2 papers)

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Research

11 pages, 282 KiB  
Article
One Year Follow-Up Assessment of Impact of Rigorous Diet Regimen and Adequate C-PAP Therapy on Obese Patients with Obstructive Sleep Apnea Syndrome: A Retrospective Study
by Pierluigi Carratù, Silvano Dragonieri, Vitaliano Nicola Quaranta, Onofrio Resta, Piero Portincasa, Vincenzo Ostilio Palmieri and Giovanna Elisiana Carpagnano
J. Clin. Med. 2024, 13(21), 6360; https://doi.org/10.3390/jcm13216360 - 24 Oct 2024
Viewed by 465
Abstract
Background/Objectives: This study evaluated the impact of continuous positive airway pressure (C-PAP) therapy combined with a rigorous diet regimen on obese patients with obstructive sleep apnea syndrome (OSAS). Methods: Sixty obese patients (BMI ≥ 30) diagnosed with severe OSAS were recruited in order [...] Read more.
Background/Objectives: This study evaluated the impact of continuous positive airway pressure (C-PAP) therapy combined with a rigorous diet regimen on obese patients with obstructive sleep apnea syndrome (OSAS). Methods: Sixty obese patients (BMI ≥ 30) diagnosed with severe OSAS were recruited in order to establish the evaluation of CPAP therapy with different extents of adherence to a rigorous diet regimen. After one year, significant improvements were observed. Results: BMI reduced by 12.32%, apnea–hypopnea index (AHI) by 22.04%, oxygen desaturation index (ODI) by 15.87%, total sleep time with oxygen saturation below 90% (TST90%) by 25.2%, and Epworth Sleepiness Scale (ESS) scores by 21.74%. Patients were, then, divided into three groups, based on adherence to the restricted diet, as well as to the correct use of the nocturnal C-PAP, showing different reductions in BMI, AHI, ODI, TST90%, and ESS, according to their adherence, based on the sum of % reduction in BMI + AHI into three groups. Conclusions: These findings underscore the effectiveness of combining C-PAP therapy with a strict diet in improving OSAS symptoms and overall health in obese patients. Future studies with larger cohorts and longer follow-up periods are needed to confirm these results and explore the long-term benefits of this integrated approach. Full article
(This article belongs to the Special Issue Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS))
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12 pages, 1970 KiB  
Article
Validation of the European Obstructive Sleep Apnea Screening (EUROSAS) in Professional Male Drivers
by Yeliz Celik, Semih Arbatli, Baran Balcan and Yuksel Peker
J. Clin. Med. 2024, 13(19), 5976; https://doi.org/10.3390/jcm13195976 - 8 Oct 2024
Viewed by 617
Abstract
(1) Background: The European Union Driver License Committee recently developed a questionnaire as a screening tool for obstructive sleep apnea (OSA), named the European Obstructive Sleep Apnea Screening (EUROSAS) questionnaire for drivers. The aim of the current study was to investigate the diagnostic [...] Read more.
(1) Background: The European Union Driver License Committee recently developed a questionnaire as a screening tool for obstructive sleep apnea (OSA), named the European Obstructive Sleep Apnea Screening (EUROSAS) questionnaire for drivers. The aim of the current study was to investigate the diagnostic performance of the EUROSAS to predict risk of OSA in professional male drivers. (2) Methods: Fifty-eight drivers were included in the current study. All participants were asked to fill out the EUROSAS before an overnight polysomnography (PSG) in the hospital. OSA was defined as an apnea-hypopnea index (AHI) 5 events/hour on the PSG. (3) Results: Out of 58 participants, the EUROSAS correctly identified 39 (67.2%) cases as having high-risk OSA and one patient as having low-risk OSA, using AHI ≥ 5 events/h. The results indicated that the EUROSAS has a sensitivity of 67.2%, a specificity of 33.3%, a positive predictive value of 94.8%, and a negative predictive value of 5.2%. Similar results were obtained using AHI cut-offs of 15 and 30 events/h. (4) Conclusions: The EUROSAS provides a moderate level of accuracy for the screening of OSA in the professional male drivers. It seems that the diagnostic performance of the EUROSAS is not promising as an alternative questionnaire to identify professional drivers with OSA, probably due to participant response bias. Despite its limited evidence, the EUROSAS might have potential as a clinical screening tool in the general population. Full article
(This article belongs to the Special Issue Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS))
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