Biomedical Composites: Material Science and Corrosion Resistance Aspects

A special issue of Journal of Composites Science (ISSN 2504-477X). This special issue belongs to the section "Biocomposites".

Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 11200

Special Issue Editor

Special Issue Information

Dear Colleagues,

The aim of the Special Issue on “Biomedical Composites: Material Science and Corrosion Resistance Aspects” is to collect high-quality papers and reviews on the theoretical and experimental study of composite biomedical materials evidencing recent progresses in material science and electrochemical biocorrosion aspects. The use of composite biomaterials is finalized to solve the constraints of single materials by highlighting their functionality in the human body environment. All research groups with different backgrounds working in this area are invited to propose to the Special Issue the development of their research on all types of biomedical composite materials with both theoretical and experimental approaches. 

Potential topics include but are not limited to:

  • Synthesis of composites for biomedical applications;
  • Composite coatings with improved biocorrosion resistance;
  • Physicochemical, electrochemical, mechanical, tribological, biological, structural and functional characterization of biomedical composites;
  • Theoretical modeling of the synthesis processes or the functioning of composite biomaterials in the human body.

Dr. Patrizia Bocchetta
Guest Editor

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Keywords

  • biomedical
  • composites
  • metal composites
  • biocorrosion

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Published Papers (5 papers)

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Research

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12 pages, 1809 KiB  
Article
Preparation and Properties of Flame-Retardant Polyurethane Pressure Sensitive Adhesive and Its Application
by Lijuan Zeng, Liu Yang, Junbang Liu, Shangkai Lu, Lianghui Ai, Yang Dong, Zhibin Ye and Ping Liu
J. Compos. Sci. 2023, 7(2), 85; https://doi.org/10.3390/jcs7020085 - 16 Feb 2023
Cited by 1 | Viewed by 2063
Abstract
Using 10-(2,5-dihydroxyphenyl)-10-hydrogen-9-oxo-10-phosphine-10-oxide (DOPO-H Q), N,N-diethyl-bis(hydroxyethyl) aminomethylene phosphate diethyl (FRC-6), and (6-oxo- 6H-dibenzo[c,e][1,2]oxphosphine-6-yl) hydroxylmethyl-thiophene (DOPO-SF) as reactive flame retardants, the flame-retardant polyurethane pressure sensitive adhesive (FRPU-PSA) were prepared. The fourier transform infrared (FTIR), thermogravimetric analysis (TG), limiting oxygen index (LOI), vertical combustion (UL 94), [...] Read more.
Using 10-(2,5-dihydroxyphenyl)-10-hydrogen-9-oxo-10-phosphine-10-oxide (DOPO-H Q), N,N-diethyl-bis(hydroxyethyl) aminomethylene phosphate diethyl (FRC-6), and (6-oxo- 6H-dibenzo[c,e][1,2]oxphosphine-6-yl) hydroxylmethyl-thiophene (DOPO-SF) as reactive flame retardants, the flame-retardant polyurethane pressure sensitive adhesive (FRPU-PSA) were prepared. The fourier transform infrared (FTIR), thermogravimetric analysis (TG), limiting oxygen index (LOI), vertical combustion (UL 94), 180° peeling, and inclined ball rolling were used to characterize and investigate the properties of FRPU-PSA. It was found that the LOI of PU/50mol%DOPO-HQ, PU/50mol%FRC-6, and PU/20wt%DOPO-SF were 30.7%, 29.3%, and 25.0%, respectively, the peel strength of PU/50mol%DOPO-HQ and PU/50mol%FRC-6 were 3.88N/25 mm and 3.42N/25 mm, respectively. FRPU-PSA not only had good bond strength, but also had good flame retardant performance. Full article
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Review

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17 pages, 3124 KiB  
Review
Biomedical Applications of Blow-Spun Coatings, Mats, and Scaffolds—A Mini-Review
by Mohammadmahdi Mobaraki, Meichen Liu, Abdul-Razak Masoud and David K. Mills
J. Compos. Sci. 2023, 7(2), 86; https://doi.org/10.3390/jcs7020086 - 17 Feb 2023
Cited by 6 | Viewed by 2150
Abstract
Human tissues and disease models require well-defined biomimetic microenvironments. During the past decade, innovative developments in materials science, microfabrication, and polymer science have provided us with the ability to manipulate cellular microenvironments for regenerative medicine and tissue engineering applications. Solution blow spinning is [...] Read more.
Human tissues and disease models require well-defined biomimetic microenvironments. During the past decade, innovative developments in materials science, microfabrication, and polymer science have provided us with the ability to manipulate cellular microenvironments for regenerative medicine and tissue engineering applications. Solution blow spinning is a facile fiber fabricating method that requires a simple apparatus, a concentrated polymer solution within a volatile solvent, and a high-pressure gas source. Commercially available airbrushes, typically used for painting and cosmetic makeup, have successfully generated a range of nanofibers and films. Applications under investigation are similar to electrospinning and include enzyme immobilization, drug delivery, filtration, infection protection, tissue engineering, and wound healing. This review will discuss fiber fabrication methods before a more detailed discussion of the potential of blow-spinning in biomedical applications. Full article
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13 pages, 2991 KiB  
Review
Potential of Polymer/Fullerene Nanocomposites for Anticorrosion Applications in the Biomedical Field
by Ayesha Kausar
J. Compos. Sci. 2022, 6(12), 394; https://doi.org/10.3390/jcs6120394 - 16 Dec 2022
Cited by 12 | Viewed by 2116
Abstract
Initially, this review presents the fundamentals of corrosion-resistant polymer/fullerene nanocomposites. Then, the potential of polymer/fullerene nanocomposites for corrosion resistance in biomedical applications is presented. In particular, anticorrosion biomedical applications of fullerene-based nanomaterials are proposed for antimicrobial applications, drug delivery, bioimaging, etc. According to [...] Read more.
Initially, this review presents the fundamentals of corrosion-resistant polymer/fullerene nanocomposites. Then, the potential of polymer/fullerene nanocomposites for corrosion resistance in biomedical applications is presented. In particular, anticorrosion biomedical applications of fullerene-based nanomaterials are proposed for antimicrobial applications, drug delivery, bioimaging, etc. According to the literature, due to the low conductivity/anticorrosion features of pristine thermoplastic polymers, conjugated polymers (polyaniline, polypyrrole, polythiophene, etc.) with high corrosion resistance performance were used. Subsequently, thermoplastic/thermosetting polymers were filled with nanoparticles to enhance their anticorrosion properties relative to those of neat polymers. Accordingly, fullerene-derived nanocomposites were found to be effective for corrosion protection. Polymer/fullerene nanocomposites with a fine dispersion and interactions revealed superior anticorrosion performance. The formation of a percolation network in the polymers/fullerenes facilitated their electron conductivity and, thus, corrosion resistance behavior. Consequently, the anticorrosion polymer/fullerene nanocomposites were applied in the biomedical field. However, this field needs to be further explored to see the full biomedical potential of anticorrosion polymer/fullerene nanocomposites. Full article
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19 pages, 3790 KiB  
Review
Carbonaceous Nanocomposites for Biomedical Applications as High-Drug Loading Nanocarriers for Sustained Delivery: A Review
by Bo Sun, Weijun Wang and Mohini Sain
J. Compos. Sci. 2022, 6(12), 379; https://doi.org/10.3390/jcs6120379 - 8 Dec 2022
Cited by 2 | Viewed by 1785
Abstract
Low drug loading and high initial burst release are common drawbacks for most polymeric nanocarriers in their biomedical applications. This review emphasizes the use of unconventional carbonaceous nanocomposites as functional carriers to improve the drug loading capacity and their capability of protecting drugs [...] Read more.
Low drug loading and high initial burst release are common drawbacks for most polymeric nanocarriers in their biomedical applications. This review emphasizes the use of unconventional carbonaceous nanocomposites as functional carriers to improve the drug loading capacity and their capability of protecting drugs from the surrounding environment. The unique properties of typical carbonaceous nanocarriers, including nanotube, graphene/graphite, fullerene, and nanodiamonds/diamond-like carbon, are presented. Advanced methods for the surface functionalization of carbonaceous nanocarriers are described, followed by a summary of the most appealing demonstrations for their efficient drug loading and sustained release in vitro or in vivo. The fundamental drug delivery concepts based on controlling mechanisms, such as targeting and stimulation with pH, chemical interactions, and photothermal induction, are discussed. Additionally, the challenges involved in the full utilization of carbonaceous nanocomposites are described, along with the future perspectives of their use for enhanced drug delivery. Finally, despite its recent emergence as a drug carrier, carbon-based nanocellulose has been viewed as another promising candidate. Its structural geometry and unique application in the biomedical field are particularly discussed. This paper, for the first time, taxonomizes nanocellulose as a carbon-based carrier and compares its drug delivery capacities with other nanocarbons. The outcome of this review is expected to open up new horizons of carbonaceous nanocomposites to inspire broader interests across multiple disciplines. Full article
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14 pages, 5359 KiB  
Review
High-Performance Corrosion-Resistant Polymer/Graphene Nanomaterials for Biomedical Relevance
by Ayesha Kausar, Ishaq Ahmad and Patrizia Bocchetta
J. Compos. Sci. 2022, 6(12), 362; https://doi.org/10.3390/jcs6120362 - 1 Dec 2022
Cited by 5 | Viewed by 2316
Abstract
Initially, pristine polymers were used to develop corrosion-resistant coatings. Later, the trend shifted to the use of polymeric nanocomposites in anti-corrosion materials. In this regard, graphene has been identified as an important corrosion-resistant nanomaterial. Consequently, polymer/graphene nanocomposites have been applied for erosion protection [...] Read more.
Initially, pristine polymers were used to develop corrosion-resistant coatings. Later, the trend shifted to the use of polymeric nanocomposites in anti-corrosion materials. In this regard, graphene has been identified as an important corrosion-resistant nanomaterial. Consequently, polymer/graphene nanocomposites have been applied for erosion protection applications. Among polymers, conducting polymers (polyaniline, polypyrrole, polythiophene, etc.) and nonconducting polymers (epoxy, poly(methyl methacrylate), etc.) have been used as matrices for anticorrosion graphene nanocomposites. The corrosion-resistant polymer/graphene nanocomposites have found several important applications in biomedical fields such as biocompatible materials, biodegradable materials, bioimplants, tissue engineering, and drug delivery. The biomedical performance of the nanomaterials depends on the graphene dispersion and interaction with the polymers and living systems. Future research on the anti-corrosion polymer/graphene nanocomposite is desirable to perceive further advanced applications in the biomedical arenas. Full article
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