Advanced Biomaterials for Drug Delivery

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Drug Delivery".

Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 2963

Special Issue Editor


E-Mail Website
Guest Editor
Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
Interests: drug delivery; nanotechnology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biomaterials have been considered for application in designing various drug delivery systems in recent decades. Because of their safety, tailorability, and suitability for various therapeutic molecules, including drugs, peptides, vaccines, antibodies, and enzymes, biomaterials have been approved for use in drug delivery via different administration routes. Through the functionalization of biomaterials, a wide range of drug delivery purposes could be achieved, including enhancing or controlling drug release. Targeting drug delivery systems based on biomaterials may play a crucial role in achieving high drug levels at the affected organ, with the desired therapeutic effect along with reduced toxicity. Hence, functionalized biomaterials could be applied for site-specific targeting of small or large drug molecules, which is essential for treating chronic diseases such as carcinomas, hepatic, cardiovascular diseases, etc.  

The current Special Issue aims to present original or review articles that explore applications of advanced biomaterials in drug delivery.

Topics of interest for this Special Issue include, but are not limited to, the following:

  • Sources and classes of biomaterials applied in drug delivery;
  • Safety features of biomaterial-based drug delivery systems;
  • Functionalization of biologically active molecules;
  • Biomaterials applications in various drug delivery systems;
  • Enhancing the efficacy and targeting of chemotherapeutic agents;
  • Biomaterial-based nanoparticulate drug delivery systems;
  • The role of biomaterials in pharmaceutical processing and manufacturing.

Prof. Dr. Mohamed Abbas Ibrahim
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • advanced biomaterials
  • drug delivery
  • enhanced release
  • controlled release
  • targeted release

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

12 pages, 1676 KiB  
Article
In Vitro/Ex Vivo Release Study of a Ground Umbilical Cord Matrix Loaded with Dexamethasone
by Florine Grossetete, Charlotte Garot, Emmanuel Crouzet, Xavier Delavenne, Philippe Gain, Laurence Barnouin and Gilles Thuret
J. Funct. Biomater. 2024, 15(6), 157; https://doi.org/10.3390/jfb15060157 - 5 Jun 2024
Viewed by 1076
Abstract
Eye drops containing steroids and antibiotics are widely used to treat a large range of ocular diseases of the ocular surface. They require frequent instillation or a high dosage, which can affect quality of life. We developed a biomaterial from human umbilical cord [...] Read more.
Eye drops containing steroids and antibiotics are widely used to treat a large range of ocular diseases of the ocular surface. They require frequent instillation or a high dosage, which can affect quality of life. We developed a biomaterial from human umbilical cord that can be loaded with drugs before being placed in the inferior conjunctival fornix. In the present work, this viro-inactivated, freeze-dried, and sterile foam was loaded with dexamethasone phosphate. We studied the release kinetic of 100 mg of biomaterial loaded with 100 µg of dexamethasone phosphate. Assays have shown that the product can be loaded with 100 µg of dexamethasone and allows a progressive release over time for at least 48 h. In addition, when compared with the instillation of the same dexamethasone quantity (100 µg), instilled regularly via eye-drop solution at 0.79 mg/mL, the drug penetration through corneal tissues was better with the dexamethasone-loaded biomaterial. Full article
(This article belongs to the Special Issue Advanced Biomaterials for Drug Delivery)
Show Figures

Figure 1

11 pages, 2449 KiB  
Article
Nitric Oxide Photorelease from Silicone Films Doped with N-Nitroso BODIPY
by Natalia A. Virts, Tatyana Yu. Karogodina, Mikhail A. Panfilov, Alexey Yu. Vorob’ev and Alexander E. Moskalensky
J. Funct. Biomater. 2024, 15(4), 92; https://doi.org/10.3390/jfb15040092 - 2 Apr 2024
Cited by 2 | Viewed by 1533
Abstract
Nitric oxide (NO) is a unique biochemical mediator involved in the regulation of vital processes. Light-controllable NO releasers show promise in the development of smart therapies. Here, we present a novel biocompatible material based on polydimethylsiloxane (PDMS) doped with BODIPY derivatives containing an [...] Read more.
Nitric oxide (NO) is a unique biochemical mediator involved in the regulation of vital processes. Light-controllable NO releasers show promise in the development of smart therapies. Here, we present a novel biocompatible material based on polydimethylsiloxane (PDMS) doped with BODIPY derivatives containing an N-nitroso moiety that is capable of the photoinduced generation of NO. We study the green-light-induced NO-release properties with the following three methods: electrochemical gas-phase sensor, liquid-phase sensor, and the Griess assay. Prolonged release of NO from the polymer films after short irradiation by narrow-band LED light sources and a laser beam is demonstrated. Importantly, this was accompanied by no or little release of the parent compound (BODIPY-based photodonor). Silicone films with the capability of controllable and clean NO release can potentially be used as a highly portable NO delivery system for different therapeutic applications. Full article
(This article belongs to the Special Issue Advanced Biomaterials for Drug Delivery)
Show Figures

Figure 1

Back to TopTop