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Recent Advances in Dental Implants and Biomaterials - Volume II
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Recent Advances in Dental Implants and Biomaterials - Volume II

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Dental Biomaterials".

Deadline for manuscript submissions: closed (20 February 2023) | Viewed by 4798

Special Issue Editors

Prof. Dr. Karl Kingsley

E-Mail Website
Guest Editor
School of Dental Medicine, University of Nevada, Las Vegas, NV, USA
Interests: dental materials; dental biomaterials; scaffolding; tissue engineering; biomechanics; regeneration; implants
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Neamat Hassan Abubakr

E-Mail Website
Guest Editor
Department of Biomedical Sciences, School of Dental Medicine, University of Nevada, Las Vegas, NV 89106, USA
Interests: dental material; restorative dentistry; dental pain; dental anxiety; clinical trials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recent advances in dentistry have led to improvements in diagnostic capabilities, as well as the rehabilitation of dental and oral tissues and the overall management and improvement of oral functioning. Dental biomaterials have played critical roles in these advances in rehabilitation and in the recovery of form and function.  

Many improvements have been achieved in the biomaterials used for dental amalgams and dental composites, as well as biomaterials for dental and maxillofacial grafting and tissue regeneration. The current revolution in nanotechnology and nanobiology has allowed for more innovation in the fields of bioactive glasses, resins, and polymers, with the potential for future applications in medicine and dentistry.

This Special Issue calls for recent studies from a range of fields in science and engineering that are poised to guide investigations on tissue-contacting biomaterials to control healing and advances in dental materials and their application using novel and interdisciplinary methods, and to understand mechanisms, clinical perspectives, etc., which will overall be beneficial to healthcare.

Prof. Dr. Karl Kingsley
Prof. Dr. Neamat Hassan Abubakr
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dental materials
  • dental biomaterials
  • scaffolding
  • tissue engineering
  • biomechanics
  • regeneration
  • implants
  • polymers
  • resins
  • ionomers
  • nanotechnology
  • nanobiology
  • nanotechnology
  • bioactive restorative materials

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Published Papers (2 papers)

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Research

17 pages, 1884 KiB  
Article
Differential Effects of Extracellular Matrix Glycoproteins Fibronectin and Laminin-5 on Dental Pulp Stem Cell Phenotypes and Responsiveness
by Hyungbin Lee, Allen Bae, John Kim and Karl Kingsley
J. Funct. Biomater. 2023, 14(2), 91; https://doi.org/10.3390/jfb14020091 - 8 Feb 2023
Cited by 1 | Viewed by 1720
Abstract
Dental pulp stem cells (DPSCs) are mesenchymal stem cells (MSCs) with the potential to differentiate in a limited number of other tissue types. Some evidence has suggested the modulation of DPSC growth may be mediated, in part, by exogenous extracellular matrix (ECM) glycoproteins, [...] Read more.
Dental pulp stem cells (DPSCs) are mesenchymal stem cells (MSCs) with the potential to differentiate in a limited number of other tissue types. Some evidence has suggested the modulation of DPSC growth may be mediated, in part, by exogenous extracellular matrix (ECM) glycoproteins, including fibronectin (FN) and laminin-5 (LN5). Although preliminary research suggests that some ECM glycoproteins may work as functional biomaterials to modulate DPSC growth responses, the primary goal of this project is to determine the specific effects of FN and LN5 on DPSC growth and viability. Using an existing DPSC repository, n = 16 DPSC isolates were cultured and 96-well growth assays were performed, which revealed FN, LN5 and the combination of these were sufficient to induce statistically significant changes in growth among five (n = 5) DPSC isolates. In addition, the administration of FN (either alone or in combination) was sufficient to induce the expression of alkaline phosphatase (ALP) and dentin sialophosphoprotein (DSPP), while LN5 induced the expression of ALP only, suggesting differential responsiveness among DPSCs. Moreover, these responses appeared to correlate with the expression of MSC biomarkers NANOG, Oct4 and Sox2. These results add to the growing body of evidence suggesting that functional biomaterials, such as ECM glycoproteins FN and LN5, are sufficient to induce phenotypic and differentiation-specific effects in a specific subset of DPSC isolates. More research will be needed to determine which biomarkers or additional factors are necessary and sufficient to induce the differentiation and development of DPSCs ex vivo and in vitro for biomedical applications. Full article
(This article belongs to the Special Issue Recent Advances in Dental Implants and Biomaterials - Volume II)
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16 pages, 4943 KiB  
Article
Insertion Torque, Removal Torque, and Resonance Frequency Analysis Values of Ultrashort, Short, and Standard Dental Implants: An In Vitro Study on Polyurethane Foam Sheets
by Luca Comuzzi, Margherita Tumedei, Tea Romasco, Morena Petrini, Kelvin I. Afrashtehfar, Francesco Inchingolo, Adriano Piattelli and Natalia Di Pietro
J. Funct. Biomater. 2023, 14(1), 10; https://doi.org/10.3390/jfb14010010 - 23 Dec 2022
Cited by 13 | Viewed by 2584
Abstract
Short implants were introduced to reduce morbidity, treatment duration, and complex bone regeneration interventions in atrophic jaws and to improve patient-reported outcomes. This study aimed to determine the insertion torque (IT), removal torque (RT), and resonance frequency analysis (RFA) values of ultrashort (3 [...] Read more.
Short implants were introduced to reduce morbidity, treatment duration, and complex bone regeneration interventions in atrophic jaws and to improve patient-reported outcomes. This study aimed to determine the insertion torque (IT), removal torque (RT), and resonance frequency analysis (RFA) values of ultrashort (3 mm length), short (7 mm length), and standard implants (10 mm length) inserted in 1-, 2-, 3-, and 4-mm thickness polyurethane sheets with densities of 10, 20, and 30 pounds per cubic foot (PCF). Standard-length implants were the gold standard (control). Overall, short-length implant IT values were higher or similar to the control in most experimental conditions. Those inserted into a 3 mm/30 PCF lamina showed the highest IT values, whereas 5 mm diameter ultrashort-length implants inserted into 2 and 3 mm/20 PCF laminas were higher than other implants. RT values followed the same trend and RFA values were more appreciable in short- and standard-length implants in all the scenarios. However, ultrashort-length implants reached a primary stability comparable to that of standard implants in lower thicknesses. In conclusion, although further studies are needed to corroborate this in vitro model with preclinical and clinical studies, our data shed light on short- and ultrashort-length implants geometries to a potential application in critical atrophy of the posterior jaws. Full article
(This article belongs to the Special Issue Recent Advances in Dental Implants and Biomaterials - Volume II)
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