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Technologies and Materials for Application in Dental, Oral and Maxillofacial...
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Technologies and Materials for Application in Dental, Oral and Maxillofacial Engineering

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Dental Biomaterials".

Deadline for manuscript submissions: 20 February 2025 | Viewed by 3882

Special Issue Editors

Dr. Babak Saravi

E-Mail Website
Guest Editor
1. Department of Surgery, University of Freiburg, 79098 Freiburg, Germany
2. Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Interests: imaging; CAD/CAM; biostatistics; prediction modelling; artificial intelligence; deep learning; machine learning
Special Issues, Collections and Topics in MDPI journals
Dr. Andreas Vollmer

E-Mail Website
Guest Editor
Department of Oral and Maxillofacial Surgery, University Hospital Würzburg, 97070 Würzburg, Germany
Interests: CAD/CAM; digital planning; imaging; dental technology; cancer surgery
Dr. Stefan Hartmann

E-Mail Website
Guest Editor
Department of Oral and Maxillofacial Plastic Surgery, University Hospital Würzburg, 97070 Würzburg, Germany
Interests: cancer surgery; CAD/CAM; digital planning; imaging; dental technology; artificial intelligence
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are excited to introduce an upcoming Special Issue entitled “Technologies and Materials for Application in Dental, Oral and Maxillofacial Engineering”, which will be published in the Journal of Functional Biomaterials. This Special Issue aims to provide a comprehensive platform for researchers, scientists, and practitioners to explore and discuss cutting-edge advancements in the field of dental, oral, and maxillofacial engineering.

The overarching focus of this Special Issue is to bring together diverse perspectives and insights on the integration of innovative technologies and advanced materials in dentistry and maxillofacial surgery. The scope encompasses, but is not limited to, the following:

  1. Material Advancements: novel biomaterials, including biocompatible polymers, ceramics, and composites, designed for dental and maxillofacial applications.
  2. Digital Planning and Imaging: the utilization of advanced imaging techniques, such as 3D radiography and intraoral scanning, for precise diagnosis, treatment planning, and monitoring.
  3. CAD/CAM (Computer-Aided Design and Computer-Aided Manufacturing): innovations in CAD/CAM technologies for the efficient fabrication of dental prosthetics, implants, and orthodontic devices.

This Special Issue aims to contribute to the existing literature by synthesizing state-of-the-art research and facilitating interdisciplinary discussions. By fostering collaboration between materials scientists, engineers, dentists, and oral surgeons, we hope to advance the field of dental, oral, and maxillofacial engineering, ultimately improving patient care and outcomes.

We invite researchers from various disciplines to submit their original research articles, reviews, and case studies that align with the objectives of this Special Issue. Together, we can chart new horizons in dental and maxillofacial engineering, pushing the boundaries of what is achievable in the pursuit of patient-centric care.

We look forward to your valuable contributions and the fruitful discussions that will shape the future of this field.

Warm regards,

Dr. Babak Saravi
Dr. Andreas Vollmer
Dr. Stefan Hartmann
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • digital planning
  • CAD/CAM
  • artificial intelligence
  • dental engineering
  • maxillofacial engineering
  • materials science
  • dental technology

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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Research

21 pages, 5147 KiB  
Article
Investigating Bioactive-Glass-Infused Gels for Enamel Remineralization: An In Vitro Study
by Zbigniew Raszewski, Katarzyna Chojnacka and Marcin Mikulewicz
J. Funct. Biomater. 2024, 15(5), 119; https://doi.org/10.3390/jfb15050119 - 29 Apr 2024
Cited by 2 | Viewed by 1663
Abstract
Objective: Dental hypersensitivity remains widespread, underscoring the need for materials that can effectively seal dental tubules. This study evaluated the potential of bioactive-glass-infused hydroxyethyl cellulose gels in this context. Methods: Five gels were synthesized, each containing 20% bioactive glass (specifically, 45S5, S53P4, Biomin [...] Read more.
Objective: Dental hypersensitivity remains widespread, underscoring the need for materials that can effectively seal dental tubules. This study evaluated the potential of bioactive-glass-infused hydroxyethyl cellulose gels in this context. Methods: Five gels were synthesized, each containing 20% bioactive glass (specifically, 45S5, S53P4, Biomin F, and Biomin C), with an additional blank gel serving as a control. Subjected to two months of accelerated aging at 37 ± 2 °C, these gels were assessed for key properties: viscosity, water disintegration time, pH level, consistency, adhesion to glass, and element release capability. Results: Across the board, the gels facilitated the release of calcium, phosphate, and silicon ions, raising the pH from 9.00 ± 0.10 to 9.7 ± 0.0—a range conducive to remineralization. Dissolution in water occurred within 30–50 min post-application. Viscosity readings showed variability, with 45S5 reaching 6337 ± 24 mPa/s and Biomin F at 3269 ± 18 mPa/s after two months. Initial adhesion for the blank gel was measured at 0.27 ± 0.04 Pa, increasing to 0.73 ± 0.06 Pa for the others over time. Gels can release elements upon contact with water (Ca− Biomin C 104.8 ± 15.7 mg/L; Na− Biomin F 76.30 ± 11.44 mg/L; P− Biomin C 2.623 ± 0.393 mg/L; Si− 45S5-45.15 ± 6.77mg/L, F− Biomin F− 3.256 ± 0.651mg/L; Cl− Biomin C 135.5 ± 20.3 mg/L after 45 min). Conclusions: These findings highlight the gels’ capacity to kickstart the remineralization process by delivering critical ions needed for enamel layer reconstruction. Further exploration in more dynamic, real-world conditions is recommended to fully ascertain their practical utility. Full article
(This article belongs to the Special Issue Technologies and Materials for Application in Dental, Oral and Maxillofacial Engineering)
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16 pages, 4806 KiB  
Article
Biological and Mechanical Performance of Dual-Setting Brushite–Silica Gel Cements
by Valentin C. Steinacker, Tobias Renner, Ib Holzmeister, Sebastian Gubik, Urs Müller-Richter, Niko Breitenbücher, Andreas Fuchs, Anton Straub, Mario Scheurer, Alexander C. Kübler and Uwe Gbureck
J. Funct. Biomater. 2024, 15(4), 108; https://doi.org/10.3390/jfb15040108 - 18 Apr 2024
Viewed by 1485
Abstract
Bone defects resulting from trauma, diseases, or surgical procedures pose significant challenges in the field of oral and maxillofacial surgery. The development of effective bone substitute materials that promote bone healing and regeneration is crucial for successful clinical outcomes. Calcium phosphate cements (CPCs) [...] Read more.
Bone defects resulting from trauma, diseases, or surgical procedures pose significant challenges in the field of oral and maxillofacial surgery. The development of effective bone substitute materials that promote bone healing and regeneration is crucial for successful clinical outcomes. Calcium phosphate cements (CPCs) have emerged as promising candidates for bone replacement due to their biocompatibility, bioactivity, and ability to integrate with host tissues. However, there is a continuous demand for further improvements in the mechanical properties, biodegradability, and bioactivity of these materials. Dual setting of cements is one way to improve the performance of CPCs. Therefore, silicate matrices can be incorporated in these cements. Silicate-based materials have shown great potential in various biomedical applications, including tissue engineering and drug delivery systems. In the context of bone regeneration, silicate matrices offer unique advantages such as improved mechanical stability, controlled release of bioactive ions, and enhanced cellular responses. Comprehensive assessments of both the material properties and biological responses of our samples were conducted. Cytocompatibility was assessed through in vitro testing using osteoblastic (MG-63) and osteoclastic (RAW 264.7) cell lines. Cell activity on the surfaces was quantified, and scanning electron microscopy (SEM) was employed to capture images of the RAW cells. In our study, incorporation of tetraethyl orthosilicate (TEOS) in dual-curing cements significantly enhanced physical properties, attributed to increased crosslinking density and reduced pore size. Higher alkoxysilyl group concentration improved biocompatibility by facilitating greater crosslinking. Additionally, our findings suggest citrate’s potential as an alternative retarder due to its positive interaction with the silicate matrix, offering insights for future dental material research. This paper aims to provide an overview of the importance of silicate matrices as modifiers for calcium phosphate cements, focusing on their impact on the mechanical properties, setting behaviour, and biocompatibility of the resulting composites. Full article
(This article belongs to the Special Issue Technologies and Materials for Application in Dental, Oral and Maxillofacial Engineering)
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