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Editorial Board Members’ Collection Series: Advanced Biomaterials for Tissue Regeneration...
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Editorial Board Members’ Collection Series: Advanced Biomaterials for Tissue Regeneration and Repair

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Tissue Engineering and Regenerative Medicine".

Deadline for manuscript submissions: closed (19 April 2024) | Viewed by 4988

Special Issue Editors

Prof. Dr. Jidong Li

E-Mail Website
Guest Editor
Research Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu, China
Interests: functional biomaterials; composite biomaterials; tissue regeneration; surface functinalization of biomaterials; antibacterial biomaterials; scaffolds
Prof. Dr. Congqin Ning

E-Mail Website
Guest Editor
College of Chemistry and Materials Science, Shanghai Normal University, Shanghai 200333, China
Interests: biomaterials; bioceramics; bone regeneration; dental restoration; osteogenic acticity; antibacterial activity
Dr. Zufu Lu

E-Mail Website
Guest Editor
School of Biomedical Engineering, University of Sydney, Sydney, NSW 2006, Australia
Interests: nanomaterial; biosensing; bioimaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce this Special Issue titled “Editorial Board Members’ Collection Series: Advanced Biomaterials for Tissue Regeneration and Repair”. This issue will comprise a collection of papers invited by the editorial board members with the aim of covering all aspects of biomaterials for tissue regeneration and repair.

Eligible submissions will include original research papers, communications, and review articles. All papers will be published fully open access after completing peer review.

Prof. Dr. Jidong Li
Prof. Dr. Congqin Ning
Dr. Zufu Lu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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Research

19 pages, 6940 KiB  
Article
Synergetic Effect of Electrical and Topographical Cues in Aniline Trimer-Based Polyurethane Fibrous Scaffolds on Tissue Regeneration
by Yinglong Zhang, Jiajing Tang, Wei Fang, Qing Zhao, Xiaoyu Lei, Jinzheng Zhang, Jieqiong Chen, Yubao Li and Yi Zuo
J. Funct. Biomater. 2023, 14(4), 185; https://doi.org/10.3390/jfb14040185 - 28 Mar 2023
Cited by 4 | Viewed by 2544
Abstract
Processibility and biodegradability of conductive polymers are major concerns when they are applied to tissue regeneration. This study synthesizes dissolvable and conductive aniline trimer-based polyurethane copolymers (DCPU) and processes them into scaffolds by using electrospinning with different patterns (random, oriented, and latticed). The [...] Read more.
Processibility and biodegradability of conductive polymers are major concerns when they are applied to tissue regeneration. This study synthesizes dissolvable and conductive aniline trimer-based polyurethane copolymers (DCPU) and processes them into scaffolds by using electrospinning with different patterns (random, oriented, and latticed). The effects of topographic cue changes on electrical signal transmission and further regulation of cell behaviors concerning bone tissue are researched. Results show that DCPU fibrous scaffolds possessed good hydrophilicity, swelling capacity, elasticity, and fast biodegradability in enzymatic liquid. In addition, the conductivity and efficiency of electrical signal transmission can be tuned by changing the surface’s topological structure. Among them, oriented DCPU scaffolds (DCPU-O) showed the best conductivity with the lowest ionic resistance value. Furthermore, the viability and proliferation results of bone mesenchymal stem cells (BMSCs) demonstrate a significant increase on three DCPU scaffolds compared to AT-free scaffolds (DPU-R). Especially, DCPU-O scaffolds exhibit superior abilities to promote cell proliferation because of their unique surface topography and excellent electroactivity. Concurrently, the DCPU-O scaffolds can synergistically promote osteogenic differentiation in terms of osteogenic differentiation and gene expression levels when combined with electrical stimulation. Together, these results suggest a promising use of DCPU-O fibrous scaffolds in the application of tissue regeneration. Full article
(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Advanced Biomaterials for Tissue Regeneration and Repair)
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14 pages, 3755 KiB  
Article
Realizing Both Antibacterial Activity and Cytocompatibility in Silicocarnotite Bioceramic via Germanium Incorporation
by Yingqi Ji, Shun Yang, Jian Sun and Congqin Ning
J. Funct. Biomater. 2023, 14(3), 154; https://doi.org/10.3390/jfb14030154 - 14 Mar 2023
Cited by 4 | Viewed by 2017
Abstract
The treatment of infective or potentially infectious bone defects is a critical problem in the orthopedic clinic. Since bacterial activity and cytocompatibility are always contrary factors, it is hard to have them both in one material. The development of bioactive materials with a [...] Read more.
The treatment of infective or potentially infectious bone defects is a critical problem in the orthopedic clinic. Since bacterial activity and cytocompatibility are always contrary factors, it is hard to have them both in one material. The development of bioactive materials with a good bacterial character and without sacrificing biocompatibility and osteogenic activity, is an interesting and valuable research topic. In the present work, the antimicrobial characteristic of germanium, GeO2 was used to enhance the antibacterial properties of silicocarnotite (Ca5(PO4)2SiO4, CPS). In addition, its cytocompatibility was also investigated. The results demonstrated that Ge–CPS can effectively inhibit the proliferation of both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), and it showed no cytotoxicity to rat bone marrow-derived mesenchymal stem cells (rBMSCs). In addition, as the bioceramic degraded, a sustainable release of germanium could be achieved, ensuring long-term antibacterial activity. The results indicated that Ge–CPS has excellent antibacterial activity compared with pure CPS, while no obvious cytotoxicity was observed, which could make it a promising candidate for the bone repair of infected bone defects. Full article
(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Advanced Biomaterials for Tissue Regeneration and Repair)
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