Dimorphic Fungal Pathogen Coccidioides and Coccidioidomycosis

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Pathogenesis and Disease Control".

Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 1344

Special Issue Editor


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Guest Editor
Division of Infectious Disease, Valley Fever Center for Excellence, The University of Arizona, Tucson, AZ 85724, USA
Interests: coccidioidomycosis; host-pathogen interaction; early diagnosis of valley fever; clinical presentation of valley fever; emerging fungal infections; expanding coccidioides endemic regions; improving diagnostic tools for valley fever; fungal immunology

Special Issue Information

Dear Colleagues,

The new HBO series The Last of Us has brought attention to invasive fungal infections in humans. Coccidioidomycosis (Valley fever) is a fungal infection that affects both humans and animals. The recent reports on the expansion of coccidioidomycosis endemic regions from southwest USA to the surrounding US states has caused an increased risk of coccidioidomycosis in the affected population. The risk is particularly important in immunocompromised patients who reside in the expanding geographic regions for this fungus.

The Journal of Fungi has launched a Special Issue on “Dimorphic Fungal Pathogen: Coccidioides and Coccidioidomycosis”. In this issue, research and review manuscripts about coccidioidal pathogenesis and coccidioidomycosis are welcome. Manuscripts may describe research on host–pathogen interactions, genetic predispositions to coccidioidomycosis, coccidioidal epidemiology, expanding geographic regions for the disease, and rare clinical presentations of the disease. We encourage submission of papers describing novel therapeutic or diagnostic methods for early and prompt diagnosis of coccidioidomycosis.

Dr. Fariba Donovan
Guest Editor

Manuscript Submission Information

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Keywords

  • coccidioidomycosis
  • epidemiology of coccidioidomycosis
  • genetic predisposition to coccidioidomycosis
  • coccidioidal diagnosis

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Published Papers (1 paper)

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8 pages, 778 KiB  
Brief Report
Coccidioidomycosis in Immunocompromised at a Non-Endemic Referral Center in Mexico
by Carla M. Román-Montes, Lisset Seoane-Hernández, Rommel Flores-Miranda, Andrea Carolina Tello-Mercado, Andrea Rangel-Cordero, Rosa Areli Martínez-Gamboa, José Sifuentes-Osornio, Alfredo Ponce-de-León and Fernanda González-Lara
J. Fungi 2024, 10(6), 429; https://doi.org/10.3390/jof10060429 - 18 Jun 2024
Viewed by 958
Abstract
The incidence and distribution of coccidioidomycosis are increasing. Information scarcity is evident in Mexico, particularly in non-endemic zones and specific populations. We compared the treatment and outcomes for patients with isolated pulmonary infections and those with disseminated coccidioidomycosis, including mortality rates within six [...] Read more.
The incidence and distribution of coccidioidomycosis are increasing. Information scarcity is evident in Mexico, particularly in non-endemic zones and specific populations. We compared the treatment and outcomes for patients with isolated pulmonary infections and those with disseminated coccidioidomycosis, including mortality rates within six weeks of diagnosis. Of 31 CM cases, 71% were male and 55% were disseminated. For 42% of patients, there was no evidence of having lived in or visited an endemic region. All patients had at least one comorbidity, and 58% had pharmacologic immunosuppressants. The general mortality rate was 30%; without differences between disseminated and localized disease. In our research, we describe a CM with a high frequency of disseminated disease without specific risk factors and non-significant mortality. Exposure to endemic regions was not found in a considerable number of subjects. We consider diverse reasons for why this may be, such as climate change or migration. Full article
(This article belongs to the Special Issue Dimorphic Fungal Pathogen Coccidioides and Coccidioidomycosis)
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