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Personalized Medicine in Orthopedics and Traumatology
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Personalized Medicine in Orthopedics and Traumatology

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: 15 January 2025 | Viewed by 2172

Special Issue Editor

Dr. Mihai Dan Roman

E-Mail Website
Guest Editor
Surgical Department, Faculty of Medicine, University “Lucian Blaga” of Sibiu, 550024 Sibiu, Romania.
Interests: orthopedics; orthopedic surgery and traumatology; knee and hip injuries; knee surgery; arthroplasty sports injuries; fracture cartilage trauma surgery; knee replacement arthroplasties; shoulders; rotator cuff

Special Issue Information

Dear Colleagues,

Personalized medicine is not only about technology and specific operative devices or instruments but also about our specific decision-making processes based on both the “personality” of the patient and the “personality” of the musculoskeletal disorder.

The field of orthopedics and traumatology is undergoing a significant shift towards personalized medicine, recognizing the diverse needs of patients, ranging from highly active individuals to the elderly with degenerative conditions. This Special Issue highlights the importance of tailoring treatments to individual patients, considering factors such as age, activity level, risk factors, and specific clinical features.

With advancements in technologies like navigation, robotic surgery, and personalized implant designs, clinicians now have a broader array of options to optimize outcomes and reduce complications. However, the challenge lies in understanding the mechanisms behind individual patient responses and effectively implementing personalized approaches in clinical practice.

We invite researchers to contribute original research articles and reviews focusing on patient-specific clinical features, mechanisms of orthopedic diseases, risk stratification, and tailored treatment approaches. Emphasis is placed on exploring personalized interventions, diagnosis, and the treatment of intra- and postoperative complications and experimental treatments in orthopedics.

Join us in advancing the field of personalized orthopedics by sharing your insights and discoveries to enhance patient care and outcomes. Feel free to freely approach this theme of “personalized medicine” with your original thinking.

Dr. Mihai Dan Roman
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • outcomes
  • arthroscopy
  • infection
  • orthopedic surgery
  • traumatology
  • radiography
  • complication
  • individualized treatment
  • patient specificity

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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14 pages, 3697 KiB  
Article
Unveiling the Hidden Links: Anatomical and Radiological Insights into Primary Hip Osteoarthritis
by Valerio Tiburzi, Carlo Ciccullo, Luca Farinelli, Marco Di Carlo, Fausto Salaffi, Francesca Bandinelli and Antonio Pompilio Gigante
J. Pers. Med. 2024, 14(9), 1004; https://doi.org/10.3390/jpm14091004 - 20 Sep 2024
Cited by 1 | Viewed by 657
Abstract
Background: Hip osteoarthritis (HOA) is a disease with globally rising incidence that leads to disability and morbidity, overall, in older populations, and might be primary or secondary to numerous risk factors. The most common idiopathic HOA is generally a diagnosis of exclusion, with [...] Read more.
Background: Hip osteoarthritis (HOA) is a disease with globally rising incidence that leads to disability and morbidity, overall, in older populations, and might be primary or secondary to numerous risk factors. The most common idiopathic HOA is generally a diagnosis of exclusion, with pathogenetic mechanisms largely still misunderstood. We aimed to investigate the correlation between femoral–acetabular and spinopelvic anatomical and computed tomography (CT) characteristics, and the presence of primary OA. Methods: We retrospectively analyzed CT scans from 2019 to 2021, excluding patients under 45 years or with conditions affecting the pelvis, sacrum, or lower limbs. Femoral, acetabular, and spinopelvic parameters were measured; signs of OA were analyzed in the hip and knee joints. Patients were categorized into two groups: A (isolated hip OA) and B (no OA); patients with hip OA, also presenting knee OA, were excluded from this study. Results: In total, 232 cases were examined; statistical analyses compared CT parameters between 129 subjects from Group A and 103 patients of Group B. Group A showed a mean femoral version of 16 ± 4.53 degrees, significantly higher than Group B’s 13.16 ± 4.37 degrees (p = 0.0001). Other parameters showed no significant differences. Conclusion: This study highlights an association between femoral version and primary hip OA. Full article
(This article belongs to the Special Issue Personalized Medicine in Orthopedics and Traumatology)
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15 pages, 3026 KiB  
Systematic Review
Is the Timing of Surgery a Sufficient Predictive Factor for Outcomes in Patients with Proximal Femur Fractures? A Systematic Review
by Mihai Rădulescu, Bogdan-Radu Necula, Sandu Aurel Mironescu, Mihai Dan Roman, Alexander Schuh and Radu-Dan Necula
J. Pers. Med. 2024, 14(7), 773; https://doi.org/10.3390/jpm14070773 - 21 Jul 2024
Viewed by 1152
Abstract
(1) Background: Hip fractures are currently recognized as major public health problems, raising many issues in terms of both patients’ quality of life and the cost associated with caring for this type of fracture. Many authors debate whether to operate as soon as [...] Read more.
(1) Background: Hip fractures are currently recognized as major public health problems, raising many issues in terms of both patients’ quality of life and the cost associated with caring for this type of fracture. Many authors debate whether to operate as soon as possible or to postpone surgery until the patient is stable. The purpose of this review was to review the literature and obtain additional information about the moment of surgery, the time to surgery, length of hospital stay, and how all of these factors influence patient mortality and complications. (2) Methods: The systematic search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and PICO guidelines, using the Google Scholar platform, for articles published between 2015 and 2023. Quality assessment was performed. (3) Results: After applying the inclusion criteria, 20 articles were included in the final list. Those who had surgery within 48 h had lower in-hospital and 30-day mortality rates than those who operated within 24 h. The American Society of Anesthesiologists (ASA) score is an important predictive factor for surgical delay, length of hospital stay (LOS), complications, and mortality. (4) Conclusions: Performing surgery in the first 48 h after admission is beneficial to patients after medical stabilization. Avoidance of delayed surgery will improve postoperative complications, LOS, and mortality. Full article
(This article belongs to the Special Issue Personalized Medicine in Orthopedics and Traumatology)
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