Challenges and New Strategies in the Management of Gliomas
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".
Deadline for manuscript submissions: 25 July 2025 | Viewed by 1040
Special Issue Editors
Interests: central nervous system plasticity; glioblastoma microenvironment; tumor–glia inter-action; blood–brain barrier; peripheral nerve injury
Special Issues, Collections and Topics in MDPI journals
Interests: neuroanatomy; neuroscience; neuropeptides; neural stem cells; identification of carcinogenic bi-omarkers; study of molecular mechanisms involved in cancers progression
Special Issues, Collections and Topics in MDPI journals
Interests: cell differentiation; tissue homeostasis; organ remodeling; organ-on-chip; cell stress; chaperones; heat shock proteins; chaperonopathies; exosomes; glioblastoma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
High-grade gliomas represent a unique challenge for research. The tumors grow as masqued behind a plethora of neurological signs and their systemic effects. The intra-tumor and inter-tumor heterogeneity and the alliance with brain elements reveal them at an advanced stage. Surgery is possible depending on the neuro-anatomical location. Recurrent neoplastic cores often arise in the peritumoral area beyond the primary resection. Resistance to chemo and radiotherapy makes them very difficult to treat.
Despite advances in personalized medicine, immunotherapy, and the high-precision ion beam approach, the patient prognosis remains unfavorable, requiring urgent studies to understand brain tumor biology, polarization of the microenvironment, and systemic mechanisms.
The present Special Issue aims at collecting ideas, hypotheses, and proof to identify specific biomarkers within the mechanisms occurring in the brain tumor microenvironment, offering potential avenues for central nervous system re-education, personalized medicine, early diagnosis, and non-invasive anti-tumor approaches. Journal articles, reviews, and communications are welcomed.
Dr. Assunta Virtuoso
Prof. Dr. Agata Grazia D'Amico
Dr. Celeste Caruso Bavisotto
Guest Editors
Manuscript Submission Information
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Keywords
- brain tumors
- human
- mammals
- astrocytes
- microglia
- oligodendroglia
- neuroanatomy
- neuropeptides
- imaging
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