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Outcomes for Pregnancy in a Pandemic: The Impact of COVID-19...
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Outcomes for Pregnancy in a Pandemic: The Impact of COVID-19 Vaccines on Pregnant Women and Newborns

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Epidemiology".

Deadline for manuscript submissions: closed (10 October 2024) | Viewed by 5020

Special Issue Editor

Dr. Alicia Martínez-Varea

E-Mail Website
Guest Editor
1 Department of Obstetrics and Gynaecology, La Fe University and Polytechnic Hospital, Avenida Fernando Abril Martorell 106, 46026 Valencia, Spain
2 Department of Medicine, CEU Cardenal Herrera University, 12006 Castellón de la Plana, Castellón, Spain
Interests: twin pregnancy; TTTS; fetoscopy; preterm delivery; preeclampsia; fetal ultrasound; COVID-19
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 591 million people worldwide since its identification in Wuhan, China, in 2019. Data from the coronavirus disease 2019 (COVID-19) pandemic support pregnancy as a risk factor for severe COVID-19. Specifically, high-risk pregnancies complicated by SARS-COV-2 infection are at higher risk of adverse maternal outcomes than low-risk pregnancies complicated with SARS-COV-2 infection. Additionally, COVID-19 during pregnancy is associated with adverse outcomes, such as preeclampsia, preterm birth, and stillbirth. While vertical transmission is uncommon, both obstetricians and neonatologists should be reliably informed about perinatal SARS-CoV-2 infection and its consequences.

There is a growing body of evidence to indicate that receiving a COVID-19 vaccination during pregnancy is not associated with negative perinatal outcomes. Nonetheless, data concerning vaccine safety for pregnant women and their newborns are needed. This Special Issue of the Journal of Personalized Medicine aims to update the knowledge of pregnancy and perinatal outcomes during COVID-19 pandemic. It will highlight the safety effects of COVID-19 vaccines during pregnancy, as well as the potential consequences for pregnant women and their newborns. Showcasing the latest scientific advances in respect of perinatal outcomes during the COVID-19 pandemic, as well as COVID-19 vaccination in pregnancy, will continue to pave the way towards optimized and individualized perinatal medicine for SARS-COV-2 infection.

Dr. Alicia Martínez-Varea
Guest Editor

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Keywords

  • SARS-COV-2
  • pandemic
  • pregnancy
  • obstetric complications
  • vertical transmission
  • maternal mortality
  • COVID-19 vaccines
  • maternal immunization
  • perinatal outcomes
  • breastfeeding

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Published Papers (2 papers)

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Research

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9 pages, 265 KiB  
Article
Impacts of the COVID-19 Pandemic on Anxiety and Depressive Symptoms in Pregnant Women and Related Perinatal Outcomes
by Huan Han, Luyao Wang, Wenjing Lu, Jiaqi Dong, Yinuo Dong and Hao Ying
J. Pers. Med. 2023, 13(1), 94; https://doi.org/10.3390/jpm13010094 - 30 Dec 2022
Cited by 1 | Viewed by 1797
Abstract
To evaluate the impacts of the COVID-19 pandemic on anxiety and depression symptoms in pregnant women and their relationship with pregnancy outcomes, 1087 pregnant women completed online questionnaires. Anxiety symptoms were measured using the Self-Rating Anxiety Scale (SAS). Depression was assessed using the [...] Read more.
To evaluate the impacts of the COVID-19 pandemic on anxiety and depression symptoms in pregnant women and their relationship with pregnancy outcomes, 1087 pregnant women completed online questionnaires. Anxiety symptoms were measured using the Self-Rating Anxiety Scale (SAS). Depression was assessed using the Edinburgh Postnatal Depression Scale (EPDS), and the Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality. Univariate analysis and logistic regression analysis were used to determine the association between depression and anxiety symptoms, participants’ characteristics, and pregnancy outcomes. Of the 986 pregnant women who were included in this study, the rates of anxiety symptoms and depressive tendencies were 13.4% and 18.3%, respectively. Sleep disorder ((Adjusted odds ratio, AOR = 4.166; 95% confidence interval, CI: 2.797–6.205), time spent paying attention to the epidemic per day (≥1 h/d AOR = 1.568; 95% CI: 1.052–2.338), and the time spent with their spouses (Increase AOR = 0.629; 95% CI: 0.409–0.967) were associated with the risk of anxiety. Sleep disorder (AOR = 3.839; 95% CI: 2.718–5.432) and educational level (bachelor’s degree or above AOR = 1.833; 95% CI: 1.004–3.345) were associated with the risk of depression. Psychological status was not correlated with the pregnancy outcomes (p > 0.05). Anxiety and depression symptoms were common among pregnant women during the COVID-19 pandemic. Special attention should be paid to manage their risk factors. Full article
(This article belongs to the Special Issue Outcomes for Pregnancy in a Pandemic: The Impact of COVID-19 Vaccines on Pregnant Women and Newborns)

Review

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29 pages, 633 KiB  
Review
An Update on COVID-19 Vaccination and Pregnancy
by Cristina Juliá-Burchés and Alicia Martínez-Varea
J. Pers. Med. 2023, 13(5), 797; https://doi.org/10.3390/jpm13050797 - 6 May 2023
Cited by 5 | Viewed by 2277
Abstract
Pregnant women are more prone to experience severe COVID-19 disease, including intensive care unit (ICU) admission, use of invasive ventilation, extracorporeal membrane oxygenation (ECMO), and mortality compared to non-pregnant individuals. Additionally, research suggests that SARS-CoV-2 infection during pregnancy is linked to adverse pregnancy [...] Read more.
Pregnant women are more prone to experience severe COVID-19 disease, including intensive care unit (ICU) admission, use of invasive ventilation, extracorporeal membrane oxygenation (ECMO), and mortality compared to non-pregnant individuals. Additionally, research suggests that SARS-CoV-2 infection during pregnancy is linked to adverse pregnancy outcomes, such as preterm birth, preeclampsia, and stillbirth, as well as adverse neonatal outcomes, including hospitalization and admission to the neonatal intensive care unit. This review assessed the available literature from November 2021 to 19 March 2023, concerning the safety and effectiveness of COVID-19 vaccination during pregnancy. COVID-19 vaccination administered during pregnancy is not linked to significant adverse events related to the vaccine or negative obstetric, fetal, or neonatal outcomes. Moreover, the vaccine has the same effectiveness in preventing severe COVID-19 disease in pregnant individuals as in the general population. Additionally, COVID-19 vaccination is the safest and most effective method for pregnant women to protect themselves and their newborns from severe COVID-19 disease, hospitalization, and ICU admission. Thus, vaccination should be recommended for pregnant patients. While the immunogenicity of vaccination in pregnancy appears to be similar to that in the general population, more research is needed to determine the optimal timing of vaccination during pregnancy for the benefit of the neonate. Full article
(This article belongs to the Special Issue Outcomes for Pregnancy in a Pandemic: The Impact of COVID-19 Vaccines on Pregnant Women and Newborns)
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