Nanomedicine in Cancer Therapy: What's New
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 9484
Special Issue Editor
Special Issue Information
Dear Colleagues,
I am honored to serve as a Guest Editor for this Special Issue of the Journal of Personalized Medicine entitled “Nanomedicine in Cancer Therapy: What's New”. Despite the significant progress achieved in the field of personalized cancer nanomedicine, the gap is still wide between preclinical research and clinical application. In addition, the potential of discovering several milestone pathways in the battle against cancer, including the inhibition of PD-1 and CTLA-4 by immune checkpoint inhibitors, CRIPR/Cas9 gene editing machinery, and novel tumor targeting approaches, is expected to be fully unleashed when these advanced therapeutics are combined with the clinical application of personalized nanomedicine. Several barriers that slow down the translation of nanomedicine-based research to the clinic need to be rationally discussed and investigated. Research in this field should not only focus on developing new and ‘smarter’ therapeutics, but also should extend to developing new ex vivo and in vivo cancer models, utilizing techniques such as 3D printing and bioprinting, and high-throughput screening, genotyping, and sequencing, to accurately represent patient-to-patient tumor heterogeneity and individual variability. Advances in nanomedicine application should not only be restricted to cancer therapy, but also extend to imaging and diagnostics. In this new Special Issue, we welcome review or research articles on novel trends in personalized cancer nanomedicine, especially when combined with new treatment venues with small molecules, macromolecules, and gene therapy, state-of-the-art technologies such as 3D bioprinting, and advanced theranostics.
Dr. Youssef W. Naguib
Guest Editor
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Keywords
- nanomaterials
- nanomedicine
- enhanced permeation and retention
- theranostics
- controlled release
- combination therapy
- gene therapy
- CRISPR/Cas9
- immune checkpoint inhibitors
- 3D printing
- liposomes
- nanoparticles
- smart polymers
- tumor targeting
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