The Genomics of Medicinal Plants

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Plant Science".

Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 1796

Special Issue Editors

School of Pharmacy, Xi’an Jiaotong University, Xi’an, China
Interests: genomics; transcriptomics; plastid genomics; evolutionary biology; population genomics
Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), College of Life Sciences, Northwest University, Xi’an, China
Interests: genomics; plastid genomics; evolutionary biology; population genomics

Special Issue Information

Dear Colleagues,

Medicinal plants are important natural resources for the development of new drugs. Understanding the genetic background of medicinal plants will provide a broad prospect for the scientific development and efficient utilization of medicinal plant resources. The advent of sequencing technologies and bioinformatics tools has substantially increased our ability to obtain plant genomes and helped us to reveal the genetic composition of plant species with important medicinal value. Although there have been many studies on the genomes of medicinal plants, a large number of valuable medicinal plant genomic resources still require sorting, in order to protect human health and social development. The purpose of this Special Issue is to report on the genomics of medicinal plants. This includes, but is not limited to, genome sequencing, genome assembly, genome structure and organization, gene prediction, genetic and physical mapping, comparative genomics, evolutionary genomics, population genomics, gene editing, DNA resequencing, exome sequencing, RNA sequencing, expression profile, gene functions, epigenomics, SNP screening, genome-wide association studies, plastid genomics and genomic selection or prediction. Bioinformatics tools and databases that facilitate the analyses of the genomic data of medicinal plants are also welcome.

Dr. Tao Zhou
Dr. Xiao Zhang
Guest Editors

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Keywords

  • medicinal plants
  • genomics
  • transcriptomics
  • plastid genomics

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Published Papers (1 paper)

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Research

13 pages, 1754 KiB  
Article
Integrating Full-Length and Second-Generation Transcriptomics to Reveal Differentially Expressed Genes Associated with the Development of Corydalis yanhusuo Tuber
by Xueyan Zhao, Li Wang, Yafu Zhou, Qing Wang, Fangyuan Wang and Yan Li
Life 2023, 13(11), 2207; https://doi.org/10.3390/life13112207 - 14 Nov 2023
Viewed by 1148
Abstract
Corydalis yanhusuo is a medicinal herb in China that has been widely used to treat various kinds of pain. The tuber is the main organ of C. yanhusuo used for medicinal purposes, but changes in related genes during the development of the tuber [...] Read more.
Corydalis yanhusuo is a medicinal herb in China that has been widely used to treat various kinds of pain. The tuber is the main organ of C. yanhusuo used for medicinal purposes, but changes in related genes during the development of the tuber have rarely been reported. To identify the differentially expressed genes during tuber development, C. yanhusuo full-length transcriptomic sequencing was performed using single-molecule real-time technology, and tubers at three development stages were selected for comparative transcriptome analysis. A total of 90,496 full-length non-chimeric transcripts were obtained, and 19,341 transcripts were annotated in at least one public database. A total of 9221 differentially expressed genes were identified during the swelling process of C. yanhusuo tuber. A Kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment analysis revealed that differentially expressed genes associated with a “starch and sucrose metabolism pathway”, “phenylpropanoid biosynthesis pathway”, “isoquinoline alkaloid biosynthesis pathway”, “zeatin biosynthesis pathway”, and “brassinosteroid biosynthesis pathway” were predominantly enriched. In addition, the genes involved in cell wall metabolism were potentially associated with tuber swelling. These processes regulated and were involved in C. yanhusuo tuber development. The results provide a foundation for further research on tuber formation in medicinal plants. Full article
(This article belongs to the Special Issue The Genomics of Medicinal Plants)
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