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9.6
4.9
Journals
Marine Drugs
Special Issues
Natural Products from Marine Bacteria
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Natural Products from Marine Bacteria

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 6730

Special Issue Editor

Prof. Dr. Chulhong Oh

E-Mail Website
Guest Editor
Jeju Marine Research Center, Korea Institute of Ocean Science and Technology, Gujwa-eup, Jeju 63349, Korea
Interests: molecular biology genetics microbiology; marine bacteria

Special Issue Information

Dear Colleagues,

In marine bacteria, natural products with new structures that are difficult to find in terrestrial bacteria are being discovered, but it is true that research is lacking compared to terrestrial bacteria. However, marine bacteria are undoubtedly an exciting resource for new natural products for drug discovery. Furthermore, compared to natural products of other marine organisms, new natural products found from marine bacteria can be easily applied industrially in terms of securing biomass stably through culturing.

This Special Issue is focused on exploring new natural products produced by marine bacteria and researching various physiological activities (antimicrobial, anticancer, antiviral, antioxidant, anti-inflammatory, etc.) of natural products.

Prof. Dr. Chulhong Oh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine bacteria
  • bioactive compounds
  • metabolite
  • natural product
  • physiological activity

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Related Special Issue

Published Papers (2 papers)

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14 pages, 1433 KiB  
Article
Taeanamides A and B, Nonribosomal Lipo-Decapeptides Isolated from an Intertidal-Mudflat-Derived Streptomyces sp.
by Jinsheng Cui, Eunji Kim, Dong Hyun Moon, Tae Ho Kim, Ilnam Kang, Yeonjung Lim, Daniel Shin, Sunghoon Hwang, Young Eun Du, Myoung Chong Song, Munhyung Bae, Jang-Cheon Cho, Jichan Jang, Sang Kook Lee, Yeo Joon Yoon and Dong-Chan Oh
Mar. Drugs 2022, 20(6), 400; https://doi.org/10.3390/md20060400 - 16 Jun 2022
Cited by 7 | Viewed by 3202
Abstract
Two new lipo-decapeptides, namely taeanamides A and B (1 and 2), were discovered from the Gram-positive bacterium Streptomyces sp. AMD43, which was isolated from a mudflat sample from Anmyeondo, Korea. The exact molecular masses of 1 and 2 were revealed by [...] Read more.
Two new lipo-decapeptides, namely taeanamides A and B (1 and 2), were discovered from the Gram-positive bacterium Streptomyces sp. AMD43, which was isolated from a mudflat sample from Anmyeondo, Korea. The exact molecular masses of 1 and 2 were revealed by high-resolution mass spectrometry, and the planar structures of 1 and 2 were elucidated using NMR spectroscopy. The absolute configurations of 1 and 2 were determined using a combined analysis of 1H-1H coupling constants and ROESY correlations, the advanced Marfey’s method, and bioinformatics. The putative nonribosomal peptide synthetase pathway for the taeanamides was identified by analyzing the full genome sequence data of Streptomyces sp. AMD43. We also found that taeanamide A exhibited mild anti-tuberculosis bioactivity, whereas taeanamide B showed significant bioactivity against several cancer cell lines. Full article
(This article belongs to the Special Issue Natural Products from Marine Bacteria)
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Review

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21 pages, 7660 KiB  
Review
Genus Nocardiopsis: A Prolific Producer of Natural Products
by Ting Shi, Yi-Fei Wang, Han Wang and Bo Wang
Mar. Drugs 2022, 20(6), 374; https://doi.org/10.3390/md20060374 - 31 May 2022
Cited by 22 | Viewed by 3106
Abstract
Actinomycetes are currently one of the major sources of bioactive secondary metabolites used for medicine development. Accumulating evidence has shown that Nocardiopsis, a key class of actinomycetes, has the ability to produce novel bioactive natural products. This review covers the sources, distribution, [...] Read more.
Actinomycetes are currently one of the major sources of bioactive secondary metabolites used for medicine development. Accumulating evidence has shown that Nocardiopsis, a key class of actinomycetes, has the ability to produce novel bioactive natural products. This review covers the sources, distribution, bioactivities, biosynthesis, and structural characteristics of compounds isolated from Nocardiopsis in the period between March 2018 and 2021. Our results reveal that 67% of Nocardiopsis-derived natural products are reported for the first time, and 73% of them are isolated from marine Nocardiopsis. The chemical structures of the Nocardiopsis-derived compounds have diverse skeletons, concentrating on the categories of polyketides, peptides, terphenyls, and alkaloids. Almost 50% of the natural products isolated from Nocardiopsis have been discovered to display various bioactivities. These results fully demonstrate the great potential of the genus Nocardiopsis to produce novel bioactive secondary metabolites that may serve as a structural foundation for the development of novel drugs. Full article
(This article belongs to the Special Issue Natural Products from Marine Bacteria)
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