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Marine Drugs publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Conotoxins: Detection, Classification and Potential Therapeutic Benefits

edited by

David Adams

and Rilei Yu

submission deadline 1 Apr 2025 | Viewed by 83 | Submission Open

Keywords: conotoxins; peptide therapeutics; targeting receptors; pharmacology; action mechanism; drug discovery; structure activity relationship; binding modes

(This special issue belongs to the Section Marine Toxins)

Enzymes from Marine By-Products and Wastes

edited by

Zied Khiari

submission deadline 15 Apr 2025 | 3 articles | Viewed by 7957 | Submission Open

Keywords: enzymes; proteases; lipases; carbohydrases; chitinases; transglutaminases; fisheries and aquaculture; by-products and waste; microbial fermentation; enzymatic hydrolysis; protein hydrolysates

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

A Deep Dive into the Ocean: Evaluation of Marine Compounds Bioactivity in the Omics Era

edited by

Elva Morretta

Maria Chiara Monti

and

Raffaella Belvedere

submission deadline 15 Apr 2025 | 3 articles | Viewed by 6491 | Submission Open

Keywords: functional proteomics; proteins expression profiling; proteins post-translational modifications analysis; metabolomics; transcriptomics; multi-omics approaches; biological activity; pharmacological profiling.

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Biologically Active Compounds from Marine Invertebrates 2025

edited by Crisalejandra Rivera-Pérez

submission deadline 15 Apr 2025 | 1 articles | Viewed by 1035 | Submission Open

Keywords: bioactive compounds; antimicrobial; antioxidants; anticancerogenic; angiotensin activity; biomedicine; biotechnology; marine natural products

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Marine Toxins: Characterization, Detection, Classification and Potential Therapeutics

edited by Robert F. Williams and Hau B. Nguyen

submission deadline 15 Apr 2025 | Viewed by 101 | Submission Open

Keywords: marine toxins; conotoxins; detection; characterization; classification; structure prediction; therapeutics; machine learning; modeling; structure design

(This special issue belongs to the Section Marine Toxins)

International Summer School of Blue Biotechnology

edited by

Chiara Lauritano

Daniela Coppola

, Donatella De Pascale and

Christian Galasso

submission deadline 15 Apr 2025 | Viewed by 84 | Submission Open

Keywords: blue biotechnology; marine (micro)organisms; fishing discards; bioactivity; marine natural products; biopolymers

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Enzymes from Marine Environments: Diversity, Characteristics, Structure, Catalytic Mechanism, Function and Application

edited by Xiulan Chen

submission deadline 15 Apr 2025 | Viewed by 82 | Submission Open

Keywords: marine enzyme; diversity; characteristics; structure; catalytic mechanism; application

Marine Anti-Inflammatory and Antioxidant Agents, 4th Edition

edited by

Donatella Degl'Innocenti

and

Marzia Vasarri

submission deadline 30 Apr 2025 | 5 articles | Viewed by 5850 | Submission Open

Keywords: marine organisms; inflammation; cytokines; antioxidant agents; anti-inflammatory gents; oxidative stress; ROS/RNS; NF-κ B; mitochondrial oxidative; drug delivery

(This special issue belongs to the Section Marine Pharmacology)

Marine Natural Products with Immunomodulatory Activity

edited by

Emiliano Manzo

submission deadline 30 Apr 2025 | 2 articles | Viewed by 4675 | Submission Open

Keywords: marine natural products; drug discovery; immune system; immunomodulatory activity; immune activation; immune modulation; structural characterization; chemical synthesis

(This special issue belongs to the Section Marine Pharmacology)

Recent Advances in Marine-Derived Pigments

edited by

Laurent Picot

and

Raimundo Gonçalves de Oliveira Junior

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4588 | Submission Open

Keywords: cancer; carotenoids; heterocycles; immunomodulation; neurodegenerative diseases; phlorotannins; phototherapy; phycobiliproteins; porphyrins; signaling pathways

(This special issue belongs to the Section Marine Pharmacology)

Chemical Defense in Marine Organisms, 3rd Edition

edited by

Chiara Lauritano

and

Adrianna Ianora

submission deadline 30 Apr 2025 | 2 articles | Viewed by 4142 | Submission Open

Keywords: defense strategies; stress responses; toxins; secondary metabolites; marine organisms; enzymatic pathway activation; bioactive compounds; biotechnological applications

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Marine-Derived Bioactive Substances and Their Mechanisms of Action

edited by

Junsei Taira

submission deadline 30 Apr 2025 | 1 articles | Viewed by 3935 | Submission Open

Keywords: marine bioactive metabolite; antioxidant; anticancer; immunomodulatory action; cell signaling; mechanisms of action

(This special issue belongs to the Section Marine Pharmacology)

Marine Algal Chemical Ecology 2024

edited by Bethanie R. Edwards

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3582 | Submission Open

Keywords: chemical ecology; marine microbiology; marine algae; omics; community dynamics

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Zebrafish Models in Marine Drug Discovery

edited by Xiaobin Li and Yun Zhang

submission deadline 30 Apr 2025 | 3 articles | Viewed by 2564 | Submission Open

Keywords: marine drugs; zebrafish model; active natural product; bioactivity screening; mechanism of action; activity evaluation

(This special issue belongs to the Section Marine Pharmacology)

Advances in Therapeutic Applications of Fish Oil, 2nd Edition

edited by

Cinzia Parolini

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1488 | Submission Open

Keywords: EPA; DHA; N-3 PUFA; marine-derived ingredients; nutraceutical; triglycerides; cardiovascular diseases; obesity; insulin resistance; metabolic syndrome

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Collection of Biosynthetic Genes from Marine Microbes

edited by

Hindra Hindra

submission deadline 30 Apr 2025 | Viewed by 449 | Submission Open

Keywords: natural product; biosynthesis; genome mining; heterologous expression; metagenomics; feeding experiments

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Microalgae Culture and Active Substance Development

edited by

Jianke Huang

and

Zhen Zhang

submission deadline 30 Apr 2025 | Viewed by 328 | Submission Open

Keywords: marine microalgae; algal active substances; cultivation optimization; photobioreactor; pigments; PUFAs (polyunsaturated fatty acids); polysaccharides; separation and purification; efficacy evaluation

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Novel Marine Antimicrobial Agents: Isolation, Synthesis, and Biological Evaluation

edited by Shengrong Liao and

Haibo Zhang

submission deadline 30 Apr 2025 | Viewed by 115 | Submission Open

Keywords: antimicrobial agent; marine compound; isolation; design & synthesis; antimicrobial activity; modification; marine origin; mechanism; marine organism; microbe

Marine Bioactive Compounds for Skin Health

edited by

Hyun Soo Kim

submission deadline 30 Apr 2025 | Viewed by 55 | Submission Open

Keywords: marine bioactive compounds; marine metabolites; skin health; skin inflammation; marine pharmaceuticals

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Pharmacognostic Potential of Seaweed Extracts and Metabolites

edited by Rafael Félix

submission deadline 30 Apr 2025 | Viewed by 49 | Submission Open

Keywords: pharmacognosy; marine natural products; bioactive compounds; human health; veterinary; agriculture; emerging diseases; antimicrobial resistance; extraction

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

Marine Polysaccharides in Medical and Biotechnological Applications

edited by

Vincenzo Zammuto

Víctor L. Campos

and

Damiano Spagnuolo

submission deadline 30 Apr 2025 | Viewed by 47 | Submission Open

Keywords: antioxidant; antimicrobial; biomedical applications; biotechnology; bioremediation; polysaccharides; phycocolloids

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Pharmaceutical Compounds Inspired by Marine Biofilms

edited by

Weipeng Zhang

submission deadline 30 Apr 2025 | Viewed by 39 | Submission Open

Keywords: marine biofilms; microorganisms; pharmaceutical compounds; genomics; metabolomics

Marine Novel Secondary Metabolites and Potential Immunomodulatory Properties

edited by

Ji-Hye Ahn

submission deadline 30 Apr 2025 | Viewed by 30 | Submission Open

Keywords: marine secondary metabolites; immunomodulation; bioactive compounds; marine pharmacology; immune response; novel therapeutics; antioxidant properties; drug discovery; natural products

(This special issue belongs to the Section Marine Pharmacology)

Toxin–Antitoxin Systems in Marine Microbiology

edited by

Yunxue Guo

submission deadline 30 Apr 2025 | Viewed by 28 | Submission Open

Keywords: toxin– antitoxin systems; marine microbiology; regulation; application; mobile genetic elements

(This special issue belongs to the Section Marine Toxins)

Marine-Derived Terpenes: Chemistry, Synthesis and Their Therapeutic Potential

edited by

Jinmei Xia

and Wenhai Xiao

submission deadline 15 May 2025 | 2 articles | Viewed by 2733 | Submission Open

Keywords: marine; terpene; structure elucidation; biosynthetic pathway; synthetic method; bioactivity; therapeutic application; anticancer; antimicrobial

(This special issue belongs to the Section Synthesis and Medicinal Chemistry of Marine Natural Products)

Marine Natural Products as Anticancer Agents 4.0

edited by

Celso Alves

and

Marc Diederich

submission deadline 15 May 2025 | 1 articles | Viewed by 1432 | Submission Open

Keywords: anticancer; anti-tumor; immune; molecular targets; co-cultures; 3D culture models; marine natural products; receptors; proteins; molecular modeling; chemical synthesis; immune-modulatory

(This special issue belongs to the Section Marine Pharmacology)

Celebrating the 100th Anniversary of Ocean University of China: Potential Therapeutic Benefits of Marine Novel Natural Products

edited by Peng Fu and

Chuanbin Shen

submission deadline 15 May 2025 | Viewed by 40 | Submission Open

Keywords: marine biotechnology; pharmacological profiling; marine anti-inflammatory agents; cancer therapeutics; infectious disease treatment; vascular disorder treatment; antithrombotic therapy; marine bioactive compounds; molecular targets; marine-derived therapeutics

(This special issue belongs to the Section Marine Pharmacology)

Marine Biotoxins 3.0

edited by

Jordi Molgó

submission deadline 31 May 2025 | 4 articles | Viewed by 6252 | Submission Open

Keywords: marine biotoxins; mechanism of action; pharmacology; cellular and molecular targets; signaling pathways; metabolism; toxicity; risk factors; molecular interactions; therapeutic potential

(This special issue belongs to the Section Marine Toxins)

Application of Marine Nature Products to Reduce Oxidative Stress

edited by

Chieh-Hsi Wu

submission deadline 31 May 2025 | 2 articles | Viewed by 2232 | Submission Open

Keywords: free radicals; inflammation; marine products; microbiota; system biology; signal transduction

(This special issue belongs to the Section Marine Pharmacology)

Bioactive Metabolites Produced by Marine Cyanobacteria and Other Microalgae

edited by

Hanna Mazur-Marzec

and

Anna Toruńska-Sitarz

submission deadline 31 May 2025 | 1 articles | Viewed by 880 | Submission Open

Keywords: cyanobacteria; microalgae; natural products; secondary metabolites; genome mining; extraction and isolation; structural analysis; biological activity; molecular targets; pharmaceutical application; biotechnological potential; toxicity

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Extremophiles: Adaptations and Biotechnological Applications

edited by

Sandra Pucciarelli

submission deadline 31 May 2025 | Viewed by 390 | Submission Open

Keywords: bioactive molecules; extremozymes; polar regions; extremophiles; biomaterials

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Sulfated Glycans

edited by

Yuefan Song

submission deadline 31 May 2025 | Viewed by 69 | Submission Open

Keywords: marine sulfated glycans; glycosaminoglycan mimetics; algal glycans; fucoidans; bioactivity; biomedical application; biomaterial

Bioactive Compounds from Marine Diatoms: Innovative Applications

edited by

Mostefa Fodil

submission deadline 31 May 2025 | Viewed by 19 | Submission Open

Keywords: marine diatoms; bioactive compounds; natural products; anticancer; anti-inflammatory; antimicrobial; antioxidants; biotechnology; marine biochemistry; drug discovery

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

New Methods in Extraction and Isolation of Marine Natural Products

edited by Débora Tomazi Pereira and Paz García-García

submission deadline 31 May 2025 | Viewed by 16 | Submission Open

Keywords: green extraction and isolation of marine natural products; marine extraction methods; isolation techniques; marine natural products; bioactive marine compounds; marine chemistry

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Marine Biomaterials for Dental Applications

edited by Marcela R. Carrilho and Walter Antonio Bretz

submission deadline 31 May 2025 | Viewed by 3 | Submission Open

Keywords: marine products; marine biomimicry; functional biomaterials; dentistry; oral health

(This special issue belongs to the Section Biomaterials of Marine Origin)

Marine Algae as Functional Foods

edited by Tânia Sofia Tavares

submission deadline 31 May 2025 | Viewed by 1 | Submission Open

Keywords: seaweed; bioactivity; extraction; sustainability; industry; food

(This special issue belongs to the Section Marine-Derived Ingredients for Drugs, Cosmeceuticals and Nutraceuticals)

High-Value-Added Resources Recovered from Marine By-Products

edited by Rong Cao and

Yongqiang Zhao

submission deadline 1 Jun 2025 | Submission Open

Keywords: marine by-products; bioactive compounds; flavor; marine enzymes; nutraceuticals; peptide isolation; polysaccharide extraction; green extraction technologies; microbial fermentation; marine biomimetics

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Antimicrobial Compounds from Marine and Island Ecosystems: Exploration, Characterization, and Application

edited by

Ruoyu Mao

and Qingfen Guan

submission deadline 15 Jun 2025 | Viewed by 32 | Submission Open

Keywords: marine and island ecosystems; antimicrobial compounds; immunomodulatory compounds; pharmaceuticals; nutraceuticals; mining; biotechnology; molecular structure; drug development

(This special issue belongs to the Section Marine Chemoecology for Drug Discovery)

Marine Algal Biotechnology and Applications

edited by

Patrizia Casella

submission deadline 15 Jun 2025 | Viewed by 19 | Submission Open

Keywords: microalgae; seaweed; alternative protein sources; fatty acids; high value compounds; biofuels; biomaterials; sustainability; circularity; biotechnologies

(This special issue belongs to the Section Marine Biotechnology Related to Drug Discovery or Production)

Diversity of Marine Fungi as a Source of Bioactive Natural Products, 2nd Edition

edited by

Dehai Li

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3053 | Submission Open

Keywords: marine fungus; bioactivity; natural products; biosynthesis; cytotoxicity; antimicrobial activity; deep sea

(This special issue belongs to the Section Structural Studies on Marine Natural Products)

Marine-Derived Novel Drugs in the Treatment of Alzheimer’s Disease

edited by Zhipei Sang

submission deadline 31 Dec 2025 | Viewed by 241 | Submission Open

Keywords: marine natural products; structural modification; target identification and validation; molecular therapy; bioactive compounds targeting AD-related targets; bioactive compounds targeting AD-related signaling pathways; high-throughput screening of bioactive compounds

(This special issue belongs to the Section Marine Pharmacology)

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