Antimicrobial Nanomaterials
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Nanomaterials and Nanotechnology".
Deadline for manuscript submissions: closed (31 December 2019) | Viewed by 37849
Special Issue Editors
Interests: nanoscale systems; supersonic beam deposition; chemical vapor deposition; self-assembly; multielement nanoparticles; biomedical, solar energy and catalysis applications.
Interests: nanoscale systems; supersonic beam deposition; chemical vapor deposition; self-assembly; multielement nanoparticles; biomedical, solar energy and catalysis applications.
Special Issue Information
Dear colleagues,
Nanostructured materials (NMs) represent an active area of research and a techno-economic sector with many application domains. The technological importance of NMs is due to their tunable physicochemical characteristics such as optical absorption, electrical and thermal conductivity and bactericidal functionalities. For the latter, a prominent attention is devoted to the wet synthesis of NMs and NPs and the study of their effect on cells and bacteria in solution. However the spreading of multi-drug-resistant pathogens by contamination through infected surfaces (medical implants such as dental or bone repair devices) has already had a large socio-economic impact. Infectious diseases caused by fungi, viruses, bacteria, and particularly by multidrug resistant bacteria have an estimated annual cost (direct and indirect) ranging from 6 to 60 billion US$ only in the US. This adds to the limited number of new antibiotics successfully developed in the last few decades, due to the difficulty of finding new antibacterial compounds with good pharmacological profiles and low toxicity.
Therefore a fundamental goal is finding appropriate materials able to kill bacteria such as metal based NPs, but is also to obtain functional nanostructured surfaces and/or thin films that can limit the spread of bacteria through surfaces. The topological and chemical characteristics of a surface determine the rate of microorganism adhesion and the response against bacteria, hence the ability to combine materials at the nanoscale is required.
This is increasing the challenge since the nanomaterial is required to have (1) microbicidal activity against a wide number of multi-drug-resistant Gram negative (G-) and Gram positive (G+) pathogens; (2) tunable mechanical properties, morphology and adhesion, to tailor the NP release and the film durability in different conditions; (3) cost-effective, environmental friendly production with high throughput.
In this framework, explored strategies are encompassing a wide range of wet synthesis techniques, while quite surprisingly less work is available exploring the potential of physical methods such as laser ablation, magnetron sputtering, gas phase beams. The aim of this Special Issue is therefore to report up to date results on antimicrobial coatings obtained by physical methods, encompassing not only the antimicrobial properties but also opening a window on the nanotoxicity issues of such coatings.
Prof. Luca Gavioli
Dr. Emanuele Cavaliere
Guest Editors
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Keywords
- nanomaterials
- antimicrobial properties
- coatings
- functional surfaces
- nanostructure mechanical properties
- wide spectrum microbicidal effect
- physical synthesis of nanoparticles
- laser ablation
- gas phase deposition
- magnetron sputtering
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