Supported Lipid Membrane Surface Modifications and Applications
A special issue of Materials (ISSN 1996-1944).
Deadline for manuscript submissions: closed (15 December 2010) | Viewed by 12135
Special Issue Editor
Department of Nanobiotechnology, Instititute for Biologocially Inspired Materials, University of Natural Resources and Life Sciences Vienna, Muthgasse 11-II, A-1190 Vienna, Austria
Interests: colloidal science; surface science; liquid interfaces; nanoscience; nanoparticles; lipid membranes; polymer brushes; biointerfaces; biosensors
Special Issues, Collections and Topics in MDPI journals
Interests: colloidal science; surface science; liquid interfaces; nanoscience; nanoparticles; lipid membranes; polymer brushes; biointerfaces; biosensors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues
Lipid membranes are versatile and convenient alternatives to study the properties of natural cell membranes. Self-assembled, artificial, substrate-supported lipid membranes have taken a central role in membrane research due to a combination of factors such as ease of creation, control over complexity, stability and the applicability of a large range of different analytical techniques. While supported lipid bilayers have been investigated for several decades, recent advances in the understanding of the assembly of such membranes from liposomes have spawned a renaissance in the field. Supported lipid bilayers are a highly promising tool to study transmembrane proteins in their native state, an application that could have tremendous impact on, e.g. drug discovery, development of biointerfaces and as platforms for glycomics and probing of multivalent binding which requires ligand mobility. Parallel advances in microfluidics, biosensor design, micro- and nanofabrication have converged to bring self-assembled supported lipid bilayers closer to a versatile and easy to use research tool as well as closer to industrial applications. The field of supported lipid bilayer research and application is thus rapidly expanding and diversifying with new platforms continuously being proposed and developed. With this issue we aim to collect state-of-the-art contributions from the wide range of research of importance to the further development of surface-tethered lipid systems and their application to scientific and technological challenges.
Dr. Erik Reimhult
Guest Editor
Lipid membranes are versatile and convenient alternatives to study the properties of natural cell membranes. Self-assembled, artificial, substrate-supported lipid membranes have taken a central role in membrane research due to a combination of factors such as ease of creation, control over complexity, stability and the applicability of a large range of different analytical techniques. While supported lipid bilayers have been investigated for several decades, recent advances in the understanding of the assembly of such membranes from liposomes have spawned a renaissance in the field. Supported lipid bilayers are a highly promising tool to study transmembrane proteins in their native state, an application that could have tremendous impact on, e.g. drug discovery, development of biointerfaces and as platforms for glycomics and probing of multivalent binding which requires ligand mobility. Parallel advances in microfluidics, biosensor design, micro- and nanofabrication have converged to bring self-assembled supported lipid bilayers closer to a versatile and easy to use research tool as well as closer to industrial applications. The field of supported lipid bilayer research and application is thus rapidly expanding and diversifying with new platforms continuously being proposed and developed. With this issue we aim to collect state-of-the-art contributions from the wide range of research of importance to the further development of surface-tethered lipid systems and their application to scientific and technological challenges.
Dr. Erik Reimhult
Guest Editor
Keywords
- supported lipid bilayer
- biosensor
- artificial membrane mimic
- surface sensitive
- patterning
- membrane protein
- surface modification
- liposome
- fusion
- lipid vesicle
- tethered membrane
- array
- cell membrane
- self assembly
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