Advances in Gut Microbiome Metabolomics

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".

Deadline for manuscript submissions: 15 May 2025 | Viewed by 175

Special Issue Editors


E-Mail Website
Guest Editor
Department of Molecular Systems Biology, Helmholtz Zentrum für Umweltforschung, 15, 04318 Leipzig, Germany
Interests: metabolomics (targeted/untargeted); human biomonitoring; microbiome research; mass spectrometry
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Helmholtz Zentrum für Umweltforschung, 15, 04318 Leipzig, Germany
Interests: targeted and untargeted metabolomics; LC-MS/MS-based methodology development; biomarkers
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Helmholtz Zentrum für Umweltforschung, 15, 04318 Leipzig, Germany
Interests: intestinal microbiome; multi-omics; metabolomics (targeted/untargeted); metaproteomics; 16S rRNA gene sequencing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The gut microbiome, a complex ecosystem of microorganisms residing in the human gastrointestinal tract, plays a crucial role in maintaining host health. Recent advances in metabolomics—a powerful tool for the comprehensive analysis of small molecules—have revolutionized our understanding of the functional outputs of the gut microbiome. This Special Issue explores the latest developments in gut microbiome metabolomics, highlighting novel methodologies, analytical techniques, and bioinformatics approaches that have enabled deeper insights into microbial metabolism and its impact on human health.

Key areas of focus include the identification of microbial-derived metabolites, their biochemical pathways, and their interactions with host systems. The integration of multi-omics data, advanced mass spectrometry, and nuclear magnetic resonance (NMR) technologies has facilitated the characterization of complex metabolite profiles, uncovering previously unknown links between the gut microbiome and various diseases, such as metabolic disorders, cancer, and neurodegenerative conditions. Additionally, this issue addresses the challenges of standardizing metabolomic analyses and the potential of personalized medicine approaches based on individual microbiome signatures.

Overall, the articles within this issue underscore the importance of gut microbiome metabolomics in advancing our understanding of microbiome-host interactions, paving the way for novel therapeutic strategies and diagnostic tools in precision medicine.

Dr. Ulrike E. Rolle-Kampczyk
Dr. Beatrice Engelmann
Dr. Sven-Bastiaan Haange
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gut microbiome–host interaction
  • cross talk
  • metabolomics
  • omics- technologies
  • microbiome signatures
  • new diagnostic tools
  • novel therapeutic strategies

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Published Papers

This special issue is now open for submission.
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