Bacteriostatic Effect of Natural Products and Their Effect on Human Metabolism
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Cell Metabolism".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 717
Special Issue Editors
Interests: natural products; molecular metabolism; secondary metabolite; pharmacokinetics; metabolic transformation
Special Issues, Collections and Topics in MDPI journals
Interests: antioxidants; oxidative stress; molecular mechanism; autophagy; ferroptosis; neurotoxicity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the past two decades, the rapid spread of antibiotic resistance and lack of effective drugs for treating life-threatening infections caused by multi-drug-resistant bacteria in animal and human medicine have forced us to find new antibacterial strategies. Natural products have served as powerful therapeutics against bacterial infection and are still an important source for the discovery of novel antibacterial drugs. To date, many natural products have been reported to exhibit potential antibacterial effects and potential molecular mechanisms remain unclear. It is well known that many natural products could directly target bacterial structures or molecules (including cell wall, secretion systems, DNA or metabolic enzymes of bacteria) to inhibit or kill bactera. Besides, some natural products could also exhibit powerful bacteriostatic effects by targeting host cells, including regulating the immue function, metabolic pathways and metabolite enrichments of host cells. For example, it has been reported that some natural products could affact host cells’ bacteriostatic effect by regulating cell autophagy or ferroptosis, which are two important metabolism-dependent cell death manners. In this Special Issue,we aim to collate innovative original research and review articles that reveal the bacteriostatic effects of natural products, potential targets, molecular mechanisms and their effects on human metabolism.
Dr. Hui Li
Dr. Chongshan Dai
Guest Editors
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Keywords
- bacteriostatic effects
- natural products
- molecular mechanisms
- target
- metabolism
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