Key Role of Drug Intervention on Diabetic Complications
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Pharmacology and Drug Metabolism".
Deadline for manuscript submissions: closed (15 December 2022) | Viewed by 6040
Special Issue Editor
Special Issue Information
Dear Colleagues,
Diabetes mellitus—a global alarmingly increasing metabolic disease—is associated with macro- and microvascular complications that adversely affect the quality of life of diabetic patients, causing increased morbidity and mortality, and posing substantial burdens to healthcare systems. Various factors other than hyperglycaemia can trigger diabetes-induced complications and are proposed as underlying pathogenic mechanisms. Therefore, targeting these pathways could be a promising therapeutic strategy for such diabetic associated lesions. Currently, in addition to insulin therapy, various treatments are used to control blood sugar through different mechanisms, such as increasing peripheral absorption of glucose, enhancement of insulin secretion and delaying carbohydrate absorption. Recently, glucagon-like peptide-1 analogues and sodium-glucose cotransporter-2 inhibitors have shown promising therapeutic efficacies in diabetic patients. High prevalence of diabetes worldwide highlights the urgent need for effective therapies.
This Special Issue welcomes submissions of studies in the field of diabetes pharmacotherapy, focusing on combating diabetic complications. Preclinical, clinical, and bioinformatics studies relevant to the field will be considered.
Dr. Nehal Elsherbiny
Guest Editor
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Keywords
- Diabetic Complications
- Pharmacotherapy
- Therapeutic Target
- Clinical
- Experimental
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