Advanced Biomaterials and Biofabrication

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B2: Biofabrication and Tissue Engineering".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 1670

Special Issue Editors


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Guest Editor
Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
Interests: 3D bioprinting; regenerative medicine; cardiac tissue engineering; bioelectronics

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Guest Editor
School of Mechanics and Safety Engineering, Zhengzhou University, Zhengzhou 450001, China
Interests: biomaterials; hydrogels; actuators; 3D bio-printing; tissue engineering
Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing 210029, China
Interests: bioactive glasses; composite hydrogels; coating; nanoparticles; tissue regeneration; additive manufacturing
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Special Issue Information

Dear Colleagues,

A variety of biomaterials, including hydrogels, bioceramics, and polypeptides, have been widely used in biomedical applications, such as bioadhesives, bioelectronics, medical implants, organ-on-chips, and drug delivery systems. The design and fabrication of predictive structures and functions are essential for the development of advanced biomaterials. It is most effective to realize the targeted composition–structure–function relationship using advanced biofabrication technologies, such as micropatterning, electrospinning, and 3D bioprinting. In light of this, there is a high demand for versatile biomaterials as well as novel biofabrication technologies, which in turn leads to new opportunities in bio-design, biomimetics, and regenerative applications.

In this perspective, this Special Issue aims to publish research articles, short communications, and topical reviews focusing on innovative biomaterials and biofabrication technologies for biomedical applications. Some relevant topics include, but are not limited to:

  • The development of novel biomaterials (e.g., dynamic hydrogels, double network hydrogels, bioactive glasses, and biodegradable metals) for biomedical applications;
  • Innovation in 3D bioprinting and other biofabrication technologies;
  • Applications of biomaterials and biofabrication (e.g., tissue engineering, drug screening, disease modeling, bioadhesives, organ-on-a-chip, bioelectronics, and other related applications).

We look forward to receiving your submissions.

Dr. Yongcong Fang
Dr. Zhongwei Guo
Dr. Kai Zheng
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • biofabrication
  • 3D bioprinting
  • tissue engineering
  • stem cell

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Published Papers (1 paper)

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Research

18 pages, 5887 KiB  
Article
Investigation of Liquid Collagen Ink for Three-Dimensional Printing
by Colten L. Snider, Chris J. Glover, David A. Grant and Sheila A. Grant
Micromachines 2024, 15(4), 490; https://doi.org/10.3390/mi15040490 - 2 Apr 2024
Cited by 1 | Viewed by 1288
Abstract
Three-dimensional printing provides more versatility in the fabrication of scaffold materials for hard and soft tissue replacement, but a critical component is the ink. The ink solution should be biocompatible, stable, and able to maintain scaffold shape, size, and function once printed. This [...] Read more.
Three-dimensional printing provides more versatility in the fabrication of scaffold materials for hard and soft tissue replacement, but a critical component is the ink. The ink solution should be biocompatible, stable, and able to maintain scaffold shape, size, and function once printed. This paper describes the development of a collagen ink that remains in a liquid pre-fibrillized state prior to printing. The liquid stability occurs due to the incorporation of ethylenediaminetetraacetic acid (EDTA) during dialysis of the collagen. Collagen inks were 3D-printed using two different printers. The resulting scaffolds were further processed using two different chemical crosslinkers, 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride)/N-hydroxysuccinimide (EDC/NHS) and genipin; gold nanoparticles were conjugated to the scaffolds. The 3D-printed scaffolds were characterized to determine their extrudability, stability, amount of AuNP conjugated, and overall biocompatibility via cell culture studies using fibroblast cells and stroma cells. The results demonstrated that the liquid collagen ink was amendable to 3D printing and was able to maintain its 3D shape. The scaffolds could be conjugated with gold nanoparticles and demonstrated enhanced biocompatibility. It was concluded that the liquid collagen ink is a good candidate material for the 3D printing of tissue scaffolds. Full article
(This article belongs to the Special Issue Advanced Biomaterials and Biofabrication)
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