Molecular Biology of Hepatitis B Virus—from Basic Concepts to Therapeutic Targets
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 14433
Special Issue Editors
Interests: hepatology; viral hepatitis; liver disease
Special Issue Information
Dear Colleagues,
Since its discovery, more than half a century ago, hepatitis B virus (HBV) has attracted the attention of clinicians and molecular virologists not only due to its significant impact on human health worldwide, but also due to the challenging task of investigating this small and yet complicated virus. For many years, the lack of appropriate molecular tools and animal models to study the virus was a major obstacle that slowed down the field. However, in recent years, seminal discoveries regarding major steps in the virus life cycle, such as its entry step and cccDNA regulation, not only enabled the development of more sophisticated tools for studying HBV, but also enhanced the efforts to find effective therapies that are able to eliminate the virus, rather than only suppress its replication.
The aim of this Special Issue is to gather the most updated information regarding the molecular biology of HBV and to connect the dots tying this information to present and future targets for curative anti-HBV therapies. We would like to invite researchers to submit their research or review articles on HBV concerning different aspects of its life cycle, with emphasis on exploiting basic concepts in HBV molecular virology for better therapeutic tools.
Dr. Amir Shlomai
Guest Editor
Manuscript Submission Information
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Keywords
- hepatitis B virus
- molecular virology
- viral hepatitis
- cccDNA
- functional cure
- viral replication
- animal models
- liver
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