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Extraction and Analysis of Natural Products in Food—2nd Edition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 2878

Special Issue Editors


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Guest Editor
Ministry of Agriculture, Food Sovereignty and Forests, CREA, Rome, Italy
Interests: bioactive compounds; polyphenols; vegetable extracts; food byproducts; nutraceutical activity; innovative extraction techniques
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Institute of Biophysics, National Research Council, Palermo, Italy
Interests: food science; natural polyphenols; antioxidant action; nutraceutical properties
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the extractive production of natural products in the food industry, especially from different food byproducts, has seen significant development, and there has also been great progress in the separation and purification techniques of natural products. Natural products include constituents present inside plants, animals, insects, and marine organisms—mainly proteins, polypeptides, amino acids, a variety of enzymes, fats, oils, monosaccharides, vitamins, alkaloids, volatile oils, flavones, organic acids, terpenoids, antibiotics, and other natural chemical constituents. Therefore, natural products have become the source of active compounds (i.e., compounds with beneficial effects on human health, such as foodborne pathogen protection, etc.), and the extraction of natural products is particularly important in multidisciplinary studies.

The aim of this Special Issue is to collect recent advances in extraction (conventional, emerging, and innovative methodologies) and analysis of natural products, including their sources, properties, and methods that have been developed to improve the extraction of compounds focusing on applications, scale-up, and process commercialization

Dr. Amenta Margherita
Dr. Valeria Guarrasi
Guest Editors

Manuscript Submission Information

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Keywords

  • natural products
  • extraction methodologies: green impacts and sustainability
  • separation and purification techniques
  • agri-food byproducts
  • natural bioactive compounds
  • food ingredients
  • industrial application

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Related Special Issue

Published Papers (3 papers)

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Research

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16 pages, 2449 KiB  
Article
Identification of Cherry Tomato Volatiles Using Different Electron Ionization Energy Levels
by Dalma Radványi, László Csambalik, Dorina Szakál and Attila Gere
Molecules 2024, 29(23), 5567; https://doi.org/10.3390/molecules29235567 - 25 Nov 2024
Viewed by 317
Abstract
A comprehensive analysis of the volatile components of 11 different cherry tomato pastes (Tesco Extra, Orange, Zebra, Yellow, Round Netherland, Mini San Marzano, Spar truss, Tesco Sunstream, Paprikakertész, Mc Dreamy, and Tesco Eat Fresh) commercially available in Hungary was performed. In order to [...] Read more.
A comprehensive analysis of the volatile components of 11 different cherry tomato pastes (Tesco Extra, Orange, Zebra, Yellow, Round Netherland, Mini San Marzano, Spar truss, Tesco Sunstream, Paprikakertész, Mc Dreamy, and Tesco Eat Fresh) commercially available in Hungary was performed. In order to ensure the reliability and accuracy of the measurement, the optimal measurement conditions were first determined. SPME (solid-phase microextraction) fiber coating, cherry tomato paste treatment, and SPME sampling time and temperature were optimized. CAR/PDMS (carboxen/polydimethylsiloxane) fiber coating with a film thickness of 85 µm is suggested at a 60 °C sampling temperature and 30 min extraction time. A total of 64 common compounds was found in the prepared, mashed cherry tomato samples, in which 59 compounds were successfully identified. Besides the already published compounds, new, cherry tomato-related compounds were found, such as 3 methyl 2 butenal, heptenal, Z-4-heptenal, E-2-heptenal, E-carveol, verbenol, limonene oxide, 2-decen-1-ol, Z-4-decen-1-al, caryophyllene oxide, and E,E-2,4-dodecadienal. Supervised and unsupervised classification methods have been used to classify the tomato varieties based on their volatiles, which identified 16 key components that enable the discrimination of the samples with a high accuracy. Full article
(This article belongs to the Special Issue Extraction and Analysis of Natural Products in Food—2nd Edition)
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20 pages, 3392 KiB  
Article
Anticoagulant Effect of Snow mountain garlic: In Vitro Evaluation of Aqueous Extract
by Isabel Clark-Montoya, Yolanda Terán-Figueroa, Denisse de Loera, Darío Gaytán-Hernández, Jorge Alejandro Alegría-Torres and Rosa del Carmen Milán-Segovia
Molecules 2024, 29(20), 4958; https://doi.org/10.3390/molecules29204958 - 20 Oct 2024
Viewed by 894
Abstract
Snow mountain garlic is traditionally eaten by Himalayan locals for its medicinal properties. Although different species of the genus Allium are known to have other biological effects, such as antiplatelet and antithrombotic activities, little is known about the anticoagulant effect of Snow mountain [...] Read more.
Snow mountain garlic is traditionally eaten by Himalayan locals for its medicinal properties. Although different species of the genus Allium are known to have other biological effects, such as antiplatelet and antithrombotic activities, little is known about the anticoagulant effect of Snow mountain garlic, a member of the genus Allium. Therefore, the present study examined the in vitro anticoagulant effect of the aqueous extract, the lyophilized aqueous extract, and the isoflavone extract from the lyophilized aqueous extract of Snow mountain garlic in samples from 50 human blood donors. Compared to the control, concentrations of 25, 12.5, and 6.25 mg/100 µL lengthened the clotting times of prothrombin, and concentrations of 25 and 12.5 mg/100 µL lengthened the activated partial thromboplastin time (p ˂ 0.05). The isoflavone extract from the lyophilized aqueous extract containing isoflavones, organosulfur compounds, a polyphenol, and a steroid glycoside showed a significant effect (p ˂ 0.05) on the prothrombin time and the activated partial thromboplastin time at a dose of 20 µL (volume) compared to the control. The results regarding the use of Snow mountain garlic as a preventive measure and aid in treating thromboembolic disease are promising. Full article
(This article belongs to the Special Issue Extraction and Analysis of Natural Products in Food—2nd Edition)
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Review

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19 pages, 843 KiB  
Review
Green Methods to Recover Bioactive Compounds from Food Industry Waste: A Sustainable Practice from the Perspective of the Circular Economy
by Vincenzo Roselli, Gianluca Pugliese, Rosalba Leuci, Leonardo Brunetti, Lucia Gambacorta, Vincenzo Tufarelli and Luca Piemontese
Molecules 2024, 29(11), 2682; https://doi.org/10.3390/molecules29112682 - 5 Jun 2024
Cited by 5 | Viewed by 1282
Abstract
The worrying and constant increase in the quantities of food and beverage industry by-products and wastes is one of the main factors contributing to global environmental pollution. Since this is a direct consequence of continuous population growth, it is imperative to reduce waste [...] Read more.
The worrying and constant increase in the quantities of food and beverage industry by-products and wastes is one of the main factors contributing to global environmental pollution. Since this is a direct consequence of continuous population growth, it is imperative to reduce waste production and keep it under control. Re-purposing agro-industrial wastes, giving them new life and new directions of use, is a good first step in this direction, and, in global food production, vegetables and fruits account for a significant percentage. In this paper, brewery waste, cocoa bean shells, banana and citrus peels and pineapple wastes are examined. These are sources of bioactive molecules such as polyphenols, whose regular intake in the human diet is related to the prevention of various diseases linked to oxidative stress. In order to recover such bioactive compounds using more sustainable methods than conventional extraction, innovative solutions have been evaluated in the past decades. Of particular interest is the use of deep eutectic solvents (DESs) and compressed solvents, associated with green techniques such as microwave-assisted extraction (MAE), ultrasonic-assisted extraction (UAE), pressurized liquid extraction (PLE) and pulsed-electric-field-assisted extraction (PEF). These novel techniques are gaining importance because, in most cases, they allow for optimizing the extraction yield, quality, costs and time. Full article
(This article belongs to the Special Issue Extraction and Analysis of Natural Products in Food—2nd Edition)
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