Metallic Radionuclides: Development and Application in Radiopharmaceutical Area
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 220
Special Issue Editors
Interests: radiometals; coordination complexes; radiopharmaceuticals; radio-therapy; imaging agents; theranostics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Radiopharmaceuticals are powerful tools for the diagnosis and treatment of oncological, cardiovascular, or neurodegenerative diseases. In addition, the opportunity of combining Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) radio-imaging and internal radiotherapy using different radionuclides incorporated in identical structures can make possible real theranostic applications, truly realizing the long-awaited “personalized medicine”.
Advances in the radiopharmaceutical field and recent technological innovation have opened perspectives to bring unique solutions to clinical demands by providing better diagnosis and more efficient therapies.
Metal radionuclides offer unprecedented features, i.e., decay modes, branching ratios, and emission types, a broad range of half-lives and energies, as well as a great variety of chemistries. Moreover, the availability of several radiometals allows for careful picking of the particular nuclear properties necessary for a number of different applications.
This is why current research for radiopharmaceutical applications of metallic radionuclides is extremely intensive, as evidenced by the plethora of highly valued scientific articles that are published every day in the field.
Given this perspective, this Special Issue of Molecules, titled “Metallic radionuclides: development and application” will accept reviews and research papers focusing on recent advances in the following topics:
- Production, separation, and purification of metallic radionuclides for radiopharmaceutical applications;
- Synthesis and preclinical/clinical evaluation of metal-based radiopharmaceuticals proposed as diagnostic/multimodal diagnostic, therapeutic, and theranostic agents;
- Synthesis and preclinical/clinical evaluation of metal-based, alpha emitter radiopharmaceuticals;
- Individualized dosimetry for metal-based theranostics.
Dr. Cristina Bolzati
Dr. Nicola Salvarese
Guest Editors
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Keywords
- radionuclide production
- radiometals
- radiopharmaceuticals
- imaging agents
- radio-therapy
- theranostics
- alpha-therapy
- radiochemistry
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