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Development and Application of Green Chemical Pesticides from Natural Sources

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Green Chemistry".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 5841

Special Issue Editors

National Engineering Research Center of Sugarcane, Fujian Agriculture and Forestry University, College of Agriculture, Fuzhou 350002, China
Interests: insect RNAi; plant-insect interaction; pest control; insect physiology and molecular biology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
The Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China
Interests: resistance management; pesticide; vegetable insect pests; mode of action; detoxification
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The use of pesticides is a common way of controlling crop diseases and insects and increasing crop yields. Natural products and their derivatives are important sources of pesticides and play crucial roles in fields such as insecticide production, bactericide development, plant growth regulation, and immune regulation. Due to their diverse sources, structures, and functions, natural products continuously provide new opportunities for pesticide research. Those products have important ecological activities in nature, playing roles as antifeedants, attractants, nematicides, fungicides, repellents, insecticides, insect growth regulators, and allelopathic agents, and can act as promising sources of novel pest control agents or biopesticides. Nowadays, natural products are not only used to confirm known pesticide targets or study their mechanisms of action but also provide a rich library of compounds that can be used to screen functional molecules based on known targets, thereby obtaining the active molecules or frameworks required for the creation of new pesticides.

This Special Issue will focus on the development and application of natural sources pesticides such as plant-derived products, microorganisms, and viruses. Potential topics include, but are not limited to: the discovery of bioactive natural source compounds, innovative synthetic approaches for bioactive nature-inspired compounds, the phytochemical profiling and bioactivity screening of natural products, mechanistic investigations of the activity or resistance of natural products, and the application of natural source products for pest control. Peer-reviewed original research articles and critical reviews will be considered for inclusion. 

Dr. Jinda Wang
Dr. Ran Wang
Guest Editors

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Keywords

  • plant-derived products
  • microorganisms
  • pest control
  • plant disease

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Published Papers (4 papers)

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Research

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11 pages, 1219 KiB  
Article
Preparation and Application of Volatilized Wormwood Essence Derived Naturally into Green Insecticide
by Shaoming Jin, Yaonan Wang, Tongtong Liu, Xiao Ning, Ruiqiang Liang, Kang Hu and Jin Cao
Molecules 2024, 29(12), 2877; https://doi.org/10.3390/molecules29122877 - 17 Jun 2024
Cited by 1 | Viewed by 944
Abstract
Naturally occurring substances and their derivatives function as vital resources for pesticides that can be used in fields, such as insecticide production and fungicide development. As a botanical entity displaying multifaceted biological functions, wormwood has received thorough scrutiny across multiple sectors. The insect [...] Read more.
Naturally occurring substances and their derivatives function as vital resources for pesticides that can be used in fields, such as insecticide production and fungicide development. As a botanical entity displaying multifaceted biological functions, wormwood has received thorough scrutiny across multiple sectors. The insect repellency potency combined with antibacterial and antifungal activities of wormwood position it as a potential candidate for prospective development into eco-friendly chemical pesticides. In this research, Wormwood essential oil was procured via ethanol water under ultrasonic scenarios and subsequently diluted with PEG 400 to formulate green chemical pesticides. The defensive efficacy of this green pesticide on plants was validated through 2 weeks of clustered plant growth experiments. Active constituents that exerted their effects were scrutinized by GC-MS. Furthermore, this green pesticide also displays efficacious effects on the prevention and management of aphids, exhibiting a dose-dependent relationship. 4-terpenol, eucalyptol, carvacrol, and L-borneol were identified by GC-MS as the predominant active constituents in this green chemical pesticide. Wormwood can be leveraged to develop green chemical pesticides, which can protect plants without contaminating the environment. Full article
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20 pages, 2826 KiB  
Article
Assessment and Optimization of the Insecticidal Properties of γ-Al2O3 Nanoparticles Derived from Mentha pulegium By-Products to Xylosandrus crassiusculus (Carob Beetle)
by Fatouma Mohamed Abdoul-Latif, Ayoub Ainane, Fatima-Ezzahra Eddabbeh, Khadija Oumaskour, Jalludin Mohamed, Ahmad Abu Arra and Tarik Ainane
Molecules 2024, 29(6), 1205; https://doi.org/10.3390/molecules29061205 - 8 Mar 2024
Viewed by 1301
Abstract
This study concentrates on assessing the insecticidal attributes of the γ-Al2O3 nanoparticles derived from the remnants of Mentha pulegium, which include essential oil, ethanolic extract, and plant waste. The synthesis of the γ-Al2O3 nanoparticles was executed [...] Read more.
This study concentrates on assessing the insecticidal attributes of the γ-Al2O3 nanoparticles derived from the remnants of Mentha pulegium, which include essential oil, ethanolic extract, and plant waste. The synthesis of the γ-Al2O3 nanoparticles was executed using a direct sol-gel procedure, affirming the crystal structure according to extensive physicochemical analyses such as UV-Vis, XRD, FTIR, and SEM. Evaluation of the insecticidal activity in vitro was conducted against Xylosandrus crassiusculus, a pest that infests carob wood, utilizing strains from diverse forests in the Khenifra region, situated in the Moroccan Middle Atlas. The lethal doses 50 ranged from 40 mg/g to 68 mg/g, indicating moderate effectiveness compared to the commercial insecticide Permethrin. Optimization of the conditions for the efficiency of the γ-Al2O3 nanoparticles was determined using experimental plans, revealing that time, humidity, and temperature were influential factors in the lethal dose 50 of these nanomaterials. Moreover, this study encompasses the establishment of correlations using Principal Component Analysis (PCA) and Ascending Hierarchical Classification (AHC) among various geographic, biological, and physical data, amalgamating geographic altitude and γ-Al2O3 nanoparticle insecticide parameters, as well as the attributes of the mechanical tests conducted on the carob wood affected by insects. The correlations highlight the close connections between the effectiveness of the insecticide, mountain altitude, and the mechanical parameters that were examined. Ultimately, these nanoparticles demonstrate promising potential as alternative insecticides, thus opening up encouraging prospects for safeguarding against carob wood pests. Full article
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Review

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10 pages, 250 KiB  
Review
Is the Biopesticide from Tea Tree Oil an Effective and Low-Risk Alternative to Chemical Pesticides? A Critical Review
by Magdalena Dziągwa-Becker and Marta Oleszek
Molecules 2024, 29(14), 3248; https://doi.org/10.3390/molecules29143248 - 9 Jul 2024
Cited by 1 | Viewed by 1442
Abstract
The use of chemical pesticides in agriculture contributes to soil, water and air pollution, biodiversity loss, and injury to non-target species. The European Commission has already established a Harmonized Risk Indicator to quantify the progress in reducing the risks linked to pesticides. Therefore, [...] Read more.
The use of chemical pesticides in agriculture contributes to soil, water and air pollution, biodiversity loss, and injury to non-target species. The European Commission has already established a Harmonized Risk Indicator to quantify the progress in reducing the risks linked to pesticides. Therefore, there is an increasing need to promote biopesticides, or so-called low-risk pesticides (LRP). Tea tree oil (TTO) is known for its antiseptic, antimicrobial, antiviral, antifungal, and anti-inflammatory properties. TTO has been extensively studied in pest management as well as in the pharmaceutical and cosmetic industry; there are already products based on its active substances on the market. This review focuses on the overall evaluation of TTO in terms of effectiveness and safety as a biopesticide for the first time. The collected data can be an added value for further evaluation of TTO in terms of the authorization extension as a fungicide in 2026. Full article
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11 pages, 578 KiB  
Review
Chalcones—Features, Identification Techniques, Attributes, and Application in Agriculture
by Magdalena Dziągwa-Becker, Marta Oleszek, Sylwia Zielińska and Wiesław Oleszek
Molecules 2024, 29(10), 2247; https://doi.org/10.3390/molecules29102247 - 10 May 2024
Cited by 1 | Viewed by 1680
Abstract
This review article is a comprehensive and current overview on chalcones, covering their sources, identification methods, and properties with a particular focus on their applications in the agricultural sector. The widespread use of synthetic pesticides has not only led to increased resistance among [...] Read more.
This review article is a comprehensive and current overview on chalcones, covering their sources, identification methods, and properties with a particular focus on their applications in the agricultural sector. The widespread use of synthetic pesticides has not only led to increased resistance among weeds and pests, resulting in economic losses, but it has also raised significant health concerns due to the overuse of these chemicals. In line with the European Green Deal 2030 and its Farm to Fork strategy, there is a targeted 50% reduction in the use of chemical pesticides by 2030, emphasizing a shift towards natural alternatives that are more environmentally sustainable and help in the restoration of natural resources. Chalcones and their derivatives, with their herbicidal, fungicidal, bactericidal, and antiviral properties, appear to be ideal candidates. These naturally occurring compounds have been recognized for their beneficial health effects for many years and have applications across multiple areas. This review not only complements the previous literature on the agricultural use of chalcones but also provides updates and introduces methods of detection such as chromatography and MALDI technique. Full article
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