Innovative and Sustainable Enzymatic Strategies Towards Chiral Products
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Green Chemistry".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 30
Special Issue Editors
Interests: stereochemistry; bioatalysis; asymmetric synthesis; green (sustainable) enzymatic chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: biocatalysis; stereoselective synthesis; immobilization of biocatalysts; flow chemistry and biocatalysis; enzyme mechanisms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
As regards compounds containing a chiral carbon atom, the desired biological effect usually resides in one of the enantiomers. Thus, there is a growing demand for enantiomerically pure biologically active products. In drug research, for instance, it is extremely important to synthesize all possible enantiomers of an active chiral compound and to analyze each of them separately. Enantiomers of pharmaceutically important compounds and their key intermediates or building blocks can be obtained through enzyme-catalyzed transformations. Using enzymes in synthetic chemistry has always been a hot topic due to the ability of enzymes to catalyze chemical transformations with high catalytic efficiency and specificity. Enzymes represent one of the leading “Green Chemistry” technologies that drive sustainable solutions in consumer products and industrial processes /ETA, 2024/. For instance, the reactions carried out under harsh conditions can be carried out faster under mild conditions (lower temperatures and pressures, neutral pH), with fewer work-up steps and higher yields. All these approaches result in improvements in efficiency and save energy.
A considerable number of simple and efficient enzymatic strategies (kinetic, dynamic kinetic, sequential kinetic resolution of racemates) for the preparation of biologically active enantiomeric compounds and their key intermediates or building blocks have been published, and most of them have been reviewed.
As a fruitful continuation of the work on the enzymatic synthesis of pharmacologically valuable compounds, in the present Special Issue, innovative and sustainable enzymatic strategies for the preparation of biologically active enantiomeric compounds or their key intermediates or building blocks will be collected.
Prof. Dr. Enikő Forró
Prof. Dr. László Poppe
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- dynamic kinetic resolution
- enzyme catalyzed transformation
- green technology
- kinetic resolution
- pharmaceutically important enantiomers
- sequential kinetic resolution
- sustainable enzymatic strategy
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
