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Dietary Fibre and Novel Carbohydrates: Extraction, Characterization, Bioactivities and Applications for Nutraceuticals Development

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (31 August 2019) | Viewed by 17619

Special Issue Editors


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Guest Editor
School of Agriculture and Food Science, University College Dublin, Belfield, Dublin 4, Ireland
Interests: gut health; animal nutrition; animal production; animal feed supplement; antimicrobial properties; natural compounds
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Agriculture and Food Science, University College Dublin, Lyons Research Farm, Celbridge, Ireland
Interests: probiotic fermentation; intestinal health; emerging extraction technologies; biological activities; antioxidant properties; biofortification; marine bioactives
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Dietary fibre is a heterogeneous group that encompasses carbohydrates of diverse chemical (e.g., lignin, inulin, chitosan, β-glucan, etc.) and structural characteristics (from small carbohydrates of 3–9 monomers to large polysaccharides). These carbohydrates have attracted the attention of the scientific community due to their multiple health benefits that could potentially be used to develop healthy functional foods and nutraceuticals. The food industry is aiming to develop novel products “rich in fibre”, as the new definition of dietary fibre includes the demonstration of the health benefits of carbohydrates in order to be considered fibre. Novel carbohydrates can be extracted from vegetal biomass (i.e., terrestrial and aquatic plants), animal sources (e.g., crustaceans) and other under-exploited (for example, algae and fungi) and waste streams from multiple food industries. This proposed Special Issue of Molecules will aim to target recent research papers, reviews, short communications, as well as perspectives in the field of the novel and biologically active carbohydrates. This Special Issue will include research on the use of innovative and emerging technologies, particularly focused on the optimization and implementation of green extraction procedures from multiple natural resources, industrial effluents and waste streams. Among others, manuscripts dealing with purification, characterisation and biological activities “in-vitro” and “ex-vivo” of these carbohydrates, along with their recent applications in emerging fields such as functional foods, animal feed, food supplements, and nutraceuticals based on structural and chemical characteristics, will also be welcomed.

Prof. John O’Doherty
Dr. Marco Garcia-Vaquero
Dr. Gaurav Rajauria
Guest Editors

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Keywords

  • dietary fibre
  • carbohydrate
  • polysaccharide
  • lignin
  • chitosan
  • extraction
  • green extraction
  • innovative technology
  • emerging technology
  • purification
  • chemical characterization
  • food
  • feed
  • functional food
  • nutraceutical
  • health benefit
  • biological activity
  • natural product

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Published Papers (3 papers)

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Research

12 pages, 1433 KiB  
Article
Psyllium (Plantago Ovata Forsk) Husk Powder as a Natural Superdisintegrant for Orodispersible Formulations: A Study on Meloxicam Tablets
by Gailute Draksiene, Dalia M. Kopustinskiene, Robertas Lazauskas and Jurga Bernatoniene
Molecules 2019, 24(18), 3255; https://doi.org/10.3390/molecules24183255 - 6 Sep 2019
Cited by 9 | Viewed by 8932
Abstract
(1) Background: In this work, we investigated the application of a natural superdisintegrant, psyllium (Plantago ovata Forsk) husk powder, for the manufacture of orodispersible meloxicam tablets. Meloxicam was chosen as a model compound for the study. (2) Methods: The tablets were prepared [...] Read more.
(1) Background: In this work, we investigated the application of a natural superdisintegrant, psyllium (Plantago ovata Forsk) husk powder, for the manufacture of orodispersible meloxicam tablets. Meloxicam was chosen as a model compound for the study. (2) Methods: The tablets were prepared using different concentrations of psyllium husk by direct compression. Bulk density, tapped density, hardness, friability, in vitro disintegration, and dissolution time tests were used to assess the quality of the formulations. (3) Results: Psyllium husk powder significantly increased the dissolution rate of meloxicam. The formulation containing 16 mg of psyllium husk powder showed the lowest wetting time, the highest water absorption ratio, and the lowest disintegration time compared to the control and to the other formulations. These effects may be attributed to the rapid uptake of water due to the vigorous swelling ability of psyllium husk powder. (4) Conclusions: The powder could be recommended as an effective natural superdisintegrant for orodispersible formulations. Full article
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16 pages, 2125 KiB  
Article
Extraction Optimization, Structural Characterization, and Antioxidant Activities of Polysaccharides from Cassia Seed (Cassia obtusifolia)
by Ding-Tao Wu, Wen Liu, Qiao-Hong Han, Ping Wang, Xian-Rong Xiang, Ye Ding, Li Zhao, Qing Zhang, Su-Qing Li and Wen Qin
Molecules 2019, 24(15), 2817; https://doi.org/10.3390/molecules24152817 - 2 Aug 2019
Cited by 37 | Viewed by 5115
Abstract
In order to explore Cassia seed polysaccharides (CSPs) as natural antioxidants for application in the functional-food industry, microwave-assisted extraction (MAE) was optimized for the extraction of CSPs by using a response surface methodology. Furthermore, the chemical structures and antioxidant activities of CSPs extracted [...] Read more.
In order to explore Cassia seed polysaccharides (CSPs) as natural antioxidants for application in the functional-food industry, microwave-assisted extraction (MAE) was optimized for the extraction of CSPs by using a response surface methodology. Furthermore, the chemical structures and antioxidant activities of CSPs extracted by MAE and hot water extraction were investigated and compared. The maximum extraction yield of CSPs extracted by MAE (8.02 ± 0.19%) was obtained at the optimized extraction parameters as follows: microwave power (415 W), extraction time (7.0 min), and ratio of water to raw material (51 mL/g). Additionally, the contents of the uronic acids, molecular weight, ratio of constituent monosaccharides, intrinsic viscosities, and degrees of esterification of CSPs were significantly affected by the MAE method. Moreover, CSPs exhibited remarkable 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) ABTS, 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl DPPH, nitric oxide, and hydroxyl radical scavenging activities as well as reducing power. The high antioxidant activities observed in CSPs extracted by MAE could be partially attributed to its low molecular weights and high content of unmethylated galacturonic acid. Results indicate that the MAE method could be an efficient technique for the extraction of CSPs with high antioxidant activity, and CSPs could be further explored as functional food ingredients. Full article
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16 pages, 3034 KiB  
Article
Bioactive Exopolysaccharides Reveal Camellia oleifera Infected by the Fungus Exobasidium gracile Could Have a Functional Use
by Zhe Dong, Wen Liu, Dejian Zhou, Peipei Li, Teng Wang, Kunlai Sun, Yuqin Zhao, Jie Wang, Bin Wang and Yin Chen
Molecules 2019, 24(11), 2048; https://doi.org/10.3390/molecules24112048 - 29 May 2019
Cited by 5 | Viewed by 2913
Abstract
Camellia oleifera is an important Chinese commercial crop. Camellia oleifera can display abnormal leaves due to infection by the parasitic fungus Exobasidium gracile. Exobasidium gracile was isolated from infected leaves and used in fermentation, and exopolysaccharides EP0-1 and EP0.5-1 were purified from [...] Read more.
Camellia oleifera is an important Chinese commercial crop. Camellia oleifera can display abnormal leaves due to infection by the parasitic fungus Exobasidium gracile. Exobasidium gracile was isolated from infected leaves and used in fermentation, and exopolysaccharides EP0-1 and EP0.5-1 were purified from the fermentation broth. EP0-1 was an alkaline polysaccharide consisting mainly of the linkages α-d-Manp(1→, →2)-α-d-Manp(1→ and →6)-α-d-Manp(1→, →3)-α-d-Glcp(1→ and→4)-α-d-Glcp(1→, terminal β-d-Galf, (1→5)-β-d-Galf, and terminal β-D-GlcN(1→. EP0.5-1 was an acidic galactofuranose-containing polysaccharide. It contained the linkages of α-d-Manp(1→, →2)-α-d-Manp(1→, →6)-α-d-Manp(1→,→2, 6)-α-d-Manp(1→, →4)-α-d-Glcp(1→, and →4)-α-d-GlcUA(1→. Galactofuranose linkages were composed of terminal β-d-Galf, (1→6)-β-d-Galf and (1→2)-β-d-Galf. Exobasidium gracile exopolysaccharides displayed significant immunoregulatory activity by activating macrophages. This research indicates that infected leaves from Camellia oleifera including the exopolysaccharides produced by the parasitic fungus Exobasidium gracile by are worth further investigation as a functional product. Full article
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