Smart Nanomaterials for Biomedical Applications, Volume II

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 3288

Special Issue Editor


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Guest Editor
Department of Physics of Polymers and Polymeric Materials, Petru Poni Institute of Macromolecular Chemistry, 41 A Grigore Ghica Voda Alley, 700487 Iasi, Romania
Interests: surface modification of polymers; DC and RF plasma; biomaterials; polymer composites; chemical and morphological characterization of polymers
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Special Issue Information

Dear Colleagues,

Materials are considered “smart” when they are “responsive” to stimuli ranging from internal biochemical cues to environmental factors (stress, temperature, humidity, pH, ionic strength, and specific chemical analytes) or to externally applied stimuli derived from magnetic or electric fields. These materials often exhibit dynamic and reversible changes in their critical physicochemical proprieties (e.g., their shape, volume, solubility, or molecular conformation), which can be repeated many times.

Novel biomaterials with enhanced performance and unique properties are required in fields such as tissue engineering, immunoengineering, cancer research, immunomodulation, drug delivery systems, and antimicrobial materials. A material’s smartness is more important if the system is highly biocompatible and has poor toxicity, and thus, depends on the physico-chemical properties of the system (e.g., its composition, shape, size, specific surface area, or surface charge). The field of smart materials is currently dominated by polymers, followed by small molecular ensembles (e.g., low-molecular-weight gelators and lipids), plasmonic/metallic or inorganic nanoparticles, and other building components of biological origin (e.g., RNA/DNA strands, proteins, and peptides).

The development of smart materials for targeted application in the biomedical field (from drug delivery systems for precision medicine, targeted therapeutics, and medicine to sensors and actuators, and ensembles for cell therapies and tissue engineering) requires the collaboration of chemists, biologists, physicists, pharmacologists, and physicians, who often have different objectives. Therefore, we invite authors working in these fields to contribute full papers, communications, and reviews to this Special Issue entitled “Smart Materials for Biomedical Applications”. This Special Issue represents an opportunity for researchers in fields ranging from material science to biomolecular design, engineering, and medical physics to combine different aspects of their work.

Dr. Magdalena Aflori
Guest Editor

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Keywords

  • biomimetic materials
  • nanocarriers
  • porous materials
  • composite materials
  • hydrogels
  • biocompatibility
  • surface modifications
  • metallic particles
  • biopolymers
  • stimuli responsive

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Published Papers (1 paper)

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Review

24 pages, 4502 KiB  
Review
Tellurium and Nano-Tellurium: Medicine or Poison?
by Daniella Sári, Aya Ferroudj, Dávid Semsey, Hassan El-Ramady, Eric C. Brevik and József Prokisch
Nanomaterials 2024, 14(8), 670; https://doi.org/10.3390/nano14080670 - 12 Apr 2024
Cited by 6 | Viewed by 2973
Abstract
Tellurium (Te) is the heaviest stable chalcogen and is a rare element in Earth’s crust (one to five ppb). It was discovered in gold ore from mines in Kleinschlatten near the present-day city of Zlatna, Romania. Industrial and other applications of Te focus [...] Read more.
Tellurium (Te) is the heaviest stable chalcogen and is a rare element in Earth’s crust (one to five ppb). It was discovered in gold ore from mines in Kleinschlatten near the present-day city of Zlatna, Romania. Industrial and other applications of Te focus on its inorganic forms. Tellurium can be toxic to animals and humans at low doses. Chronic tellurium poisoning endangers the kidney, liver, and nervous system. However, Te can be effective against bacteria and is able to destroy cancer cells. Tellurium can also be used to develop redox modulators and enzyme inhibitors. Soluble salts that contain Te had a role as therapeutic and antimicrobial agents before the advent of antibiotics. The pharmaceutical use of Te is not widespread due to the narrow margin between beneficial and toxic doses, but there are differences between the measure of toxicity based on the Te form. Nano-tellurium (Te-NPs) has several applications: it can act as an adsorptive agent to remove pollutants, and it can be used in antibacterial coating, photo-catalysis for the degradation of dyes, and conductive electronic materials. Nano-sized Te particles are the most promising and can be produced in both chemical and biological ways. Safety assessments are essential to determine the potential risks and benefits of using Te compounds in various applications. Future challenges and directions in developing nano-materials, nano-alloys, and nano-structures based on Te are still open to debate. Full article
(This article belongs to the Special Issue Smart Nanomaterials for Biomedical Applications, Volume II)
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