The Effect of Anti-inflammatory Food on Resisting Cardiocerebrovascular Diseases and Cognition
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: closed (15 September 2023) | Viewed by 10212
Special Issue Editor
Special Issue Information
Dear Colleagues,
More than 100 candidates of disease-modifying drugs for dementia have failed to be established despite the clarification of the underlying mechanisms in basic research using animal models.
Late-life dementia is characterized by multiple exacerbating factors, consisting of not only neurodegeneration but also multiple overlapping features, including vascular risk factors (e.g., hypertension, diabetes mellitus, and obesity), a history of cerebrovascular diseases, and chronic inflammation. Furthermore, neurodegeneration and cerebrovascular lesions are two leading attributable risks to the development of dementia. The neurovascular unit, which consists of the blood–brain barrier (BBB), plays an important role in the integrity of brain health. BBB dysfunction not only induces red blood cell extravasation but may also aggravate the homeostasis of the internal environment in the brain with increased inflammation and oxidative stress, all of which can lead to cognitive impairment. Improved nutrition, foods, or supplements, such as omega 3 and fish oil, can protect the blood–brain barrier integrity by reducing neuroinflammation. Thus, targeting vascular risk factors and aspects of the cerebrovascular system, such as the neurovascular unit, with improved nutrition or diets may be indispensable for the treatment or prevention of late-life dementia.
Dr. Yorito Hattori
Guest Editor
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Keywords
- vascular dementia
- vascular cognitive impairment
- Alzheimer’s dementia
- anti-inflammatory foods
- anti-inflammatory supplements
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