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Diet, Nutritional Factors and Their Effect on Different Stages of Cancer

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: closed (5 June 2024) | Viewed by 3400

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Guest Editor
Centre for Biotechnology and Fine Chemistry (CBQF), Universidade Católica Portuguesa, Porto, Portugal
Interests: nutrition; diet; inflammatory; tumorigenesis; health; anti-inflammatory dietary models; epigenetics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Diet, nutrition and food biomolecules play critical and intricate roles throughout the cancer process, contributing to its development and progression. Additionally, the maintenance of a balanced nutritional status during cancer treatment is fundamental for success in clinical outcomes. Importantly, cancer survivors and patients seek information about diet not only with the goal of improving overall health, but also to mitigate cancer-related symptoms and minimize the risk of other forms of cancer.

There are, however, several challenges in interpreting diet–cancer relationships related to methodological limitations, the heterogeneity of studies, and the need for the replication of findings. Moreover, some nutritional factors might also impact the risk of recurrence or second primary cancer in cancer patients, highlighting the need for nutritional assessments and support by healthcare professionals in the context of tertiary prevention.

This Special Issue of Nutrients, entitled “Diet, Nutritional Factors and Their Effect on Different Stages of Cancer”, aims to explore and deepen diet–cancer relationships and welcomes the submission of manuscripts unravelling the impact of diet and dietary components throughout carcinogenesis and cancer disease. Topics of interest include, but are not limited to, those described above. Manuscripts that explore new technologies and approaches, including the use of biomarkers of dietary exposure, the investigation of the molecular structure of nutritional factors and the consideration of dietary patterns, are of particular interest.

Researchers are invited to submit original research articles using any study design, including case studies, cross-sectional studies, implementation or interventional studies, cohort studies, and reviews and meta-analyses. We aim to publish a wide range of papers in this Special Issue and encourage you to submit your research. Additionally, we ask that you please share this announcement with any colleagues you think may be interested.

Dr. Marta Correia
Guest Editor

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diet
  • nutritional factor
  • cancer
  • food intake
  • bioactive molecules

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Published Papers (2 papers)

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Research

20 pages, 1073 KiB  
Article
Multifactorial Analysis of Influences on Quality of Life in Cancer Patients
by Elwira Gliwska, Dominika Głąbska, Zuzanna Zaczek, Jacek Sobocki and Dominika Guzek
Nutrients 2024, 16(18), 3207; https://doi.org/10.3390/nu16183207 - 22 Sep 2024
Viewed by 904
Abstract
Background/Objectives: The diminished quality of life experienced by cancer patients impacts not only the individuals but also the broader healthcare system. Despite the effect that cancer has on quality of life both during and after treatment, quality of life assessments are not yet [...] Read more.
Background/Objectives: The diminished quality of life experienced by cancer patients impacts not only the individuals but also the broader healthcare system. Despite the effect that cancer has on quality of life both during and after treatment, quality of life assessments are not yet commonly implemented, and the specific factors influencing quality of life are not well understood. The aim of this study was to conduct comprehensive multifactorial analysis to identify the factors that influence the quality of life in cancer patients. Methods: This study comprised a cohort of 108 patients diagnosed with cancer. The EORTC QLQ C-30 and EORTC QLQ-INFO 25 questionnaires were used to interview participants, along with questions related to disease course and lifestyle factors. Results: Differences were found in various subdomains among male versus female, individuals who solicited nutritional information in cancer themselves versus those who did not, individuals who reported consulting a dietitian versus those who did not, individuals who reported a recent decrease in their food intake versus those who did not report it. The results of the stepwise multiple regression show the following factors as the most important factors affecting their quality of life: patients soliciting nutritional information, reduced food intake, types of nutrition support, age, gender, seeking consultation with a dietitian, place of residence, and education level. Conclusions: In addition to sociodemographic variables and those related to the location, course, and treatment of cancer, including type of cancer, the variable related to patients’ declared need for soliciting nutritional information and seeking consultation with a dietitian may also influence quality of life. Therefore, the above factors in determining the quality of life and well-being of patients should also be considered in a holistic approach to patient care. Full article
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14 pages, 979 KiB  
Article
Nutritional Status Indices and Monoclonal Gammopathy of Undetermined Significance Risk in the Elderly Population: Findings from the National Health and Nutrition Examination Survey
by Linfeng Li, Mengrui Wu, Zhengyu Yu and Ting Niu
Nutrients 2023, 15(19), 4210; https://doi.org/10.3390/nu15194210 - 29 Sep 2023
Cited by 3 | Viewed by 2047
Abstract
Objective: Although several studies have found dietary intake is related to multiple myeloma (MM) and its precursor status risks, the role of one’s nutritional status has been ignored and its role in plasma cell neoplasm development is still unclear. This study aimed to [...] Read more.
Objective: Although several studies have found dietary intake is related to multiple myeloma (MM) and its precursor status risks, the role of one’s nutritional status has been ignored and its role in plasma cell neoplasm development is still unclear. This study aimed to explore the relationship between various clinical indices of nutritional status and the risk of monoclonal gammopathy of undetermined significance (MGUS) in the population. Methods: We selected 9520 participants from the NHANES III and NHANES 1999–2004 studies. Controlling nutritional status index (CONUT), prognostic nutritional index (PNI), geriatric nutritional risk index (GNRI) and body mass index (BMI) were calculated as indices of nutritional status of the participants. Associations between nutritional indices and MGUS were investigated using multiple logistic regression, subgroup analysis, and an RCS model. Results: In our study, 266 participants had MGUS, with a prevalence of 2.79%. This study found that CONUT and PNI identified populations with poor nutritional status and had a significant positive correlation with the risk of MGUS. In multivariate logistic regression, compared with the lower CONUT score (<3) group, the OR for the group with higher scores (≥3) was 1.805 (95%CI: 1.271, 2.564). Compared with the lowest quartile group, the highest quartile PNI score group had an OR of 0.509 (95%CI: 0.290, 0.896). GNRI had no significant correlation with the risk of MGUS, with an OR of 0.737 (95%CI: 0.443, 1.227). Conclusion: This study found that older adults with CONUT and PNI scores indicating poorer nutrition had a higher risk of MGUS. Full article
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