Mpox in the 21st Century

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 3037

Special Issue Editor


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Guest Editor
Division of Infectious Diseases, Saint Louis University, St. Louis, MO 63103, USA
Interests: mycobacterial diseases (TB and nontuberculous mycobacteria); respiratory viruses (influenza, RSV, COVID-19); pox infections; general clinical infectious diseases
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Special Issue Information

Dear Colleagues,

Mpox is one of the four pathogenic orthopoxvirus species. Mpox has two genetic clades, the Central African and West African clades, which have caused outbreaks in the corresponding regions of Africa since 1970. The first Mpox cases outside Africa were detected in the United States in 2003, suggesting the potential for Mpox clades to spread widely. In fact, Mpox recently caused a large outbreak involving 110 countries and locations that led the World Health Organization to declare a global health emergency in July 2022, illustrating that Mpox continues to be a serious public health threat.

In this Special Issue of Pathogens, we invite you to submit research articles, review articles, short communications, and case series or case reports on Mpox. Suggested topics include, but are not limited to, clinical presentations in individuals with different risk factors; animal reservoirs and transmission; treatment, vaccines and their impact; and ongoing studies for the potential improvement of strategies to control future outbreaks.

Dr. Getahun Abate
Guest Editor

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Keywords

  • Mpox
  • monkeypox
  • outbreak
  • treatment
  • vaccine

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Published Papers (1 paper)

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Review

21 pages, 1863 KiB  
Review
Mapping the Landscape of Health Research Priorities for Effective Pandemic Preparedness in Human Mpox Virus Disease
by Sumit Aggarwal, Pragati Agarwal, Kuldeep Nigam, Neetu Vijay, Pragya Yadav and Nivedita Gupta
Pathogens 2023, 12(11), 1352; https://doi.org/10.3390/pathogens12111352 - 14 Nov 2023
Viewed by 2534
Abstract
The global re-emergence of monkeypox (Mpox) in non-endemic regions in 2022 has highlighted the critical importance of timely virus detection and robust public health surveillance in assessing outbreaks and their impact. Despite significant Mpox research being conducted worldwide, there is an urgent need [...] Read more.
The global re-emergence of monkeypox (Mpox) in non-endemic regions in 2022 has highlighted the critical importance of timely virus detection and robust public health surveillance in assessing outbreaks and their impact. Despite significant Mpox research being conducted worldwide, there is an urgent need to identify knowledge gaps and prioritize key research areas in order to create a roadmap that maximizes the utilization of available resources. The present research article provides a comprehensive mapping of health research priorities aimed at advancing our understanding of Mpox and developing effective interventions for managing its outbreaks, and, as evidenced by the fact that achieving this objective requires close interdisciplinary collaboration. The key research priorities observed were identifying variants responsible for outbreaks; discovering novel biomarkers for diagnostics; establishing suitable animal models; investigating reservoirs and transmission routes; promoting the One Health approach; identifying targets for vaccination; gaining insight into the attitudes, experiences, and practices of key communities, including stigma; and ensuring equity during public health emergencies. The findings of this study hold significant implications for decision making by multilateral partners, including research funders, public health practitioners, policy makers, clinicians, and civil society, which will facilitate the development of a comprehensive plan not only for Mpox but also for other similar life-threatening viral infections. Full article
(This article belongs to the Special Issue Mpox in the 21st Century)
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