Green Synthesis and Biological Evaluation of Quinazolinone-Based Compounds
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 58
Special Issue Editors
Interests: deep eutectic solvents; quinazolinones; coumarins; microwave-assisted synthesis; mechanochemical synthesis; green chemistry
Interests: organic synthesis; green chemistry; medicinal chemistry; quinazolinones; glycoconjugates; ligand–receptor interactions
Interests: deep eutectic solvents; quinazolinones; coumarins; microwave-assisted synthesis; mechanochemical synthesis; green chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The conventional synthesis of different heterocycles often includes volatile organic solvents, catalysts, and energy consumption, causing the accumulation of large amounts of waste. In recent decades, green synthesis has utilized safer solvents, such as deep eutectic solvents, instead of harmful organic solvents. Due to their favorable properties, deep eutectic solvents combined with green synthetic methods can reduce or eliminate waste production, making the synthesis cleaner and faster. Quinazolinones are a class of nitrogen-containing compounds with a broad spectrum of biological activities attributed to their interactions with enzymes, receptors, and DNA. Their potential in drug discovery continues to expand, so it is important to prepare novel derivatives, making them candidates for the development of new therapeutic agents.
This Special Issue highlights recent advances in the green synthesis of quinazolinone-based compounds. Also, we welcome submissions that cover biological activities, including antimicrobial, antiproliferative, antiradical, and anti-inflammatory effects, among others. Their potential activities can be predicted by computational studies. Therefore, the synthesis and biological activity of quinazolinone-based compounds are welcomed as topics in this Special Issue, taking both research papers and reviews into consideration for publication.
Dr. Mario Komar
Dr. Marija Paurević
Dr. Maja Molnar
Guest Editors
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Keywords
- synthesis in deep eutectic solvents
- microwave-assisted synthesis
- ultrasound-assisted synthesis
- mechanochemical synthesis
- quinazolinones
- biological activity
- computational methods
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