Solubilization and Controlled Release Strategy of Poorly Water-Soluble Drugs 2024
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".
Deadline for manuscript submissions: closed (25 November 2024) | Viewed by 3245
Special Issue Editor
Interests: drug formulation; pharmaceutical technology; formulation development and characterization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The processes of solubilization and controlled release of drugs that are not very soluble in water are of great relevance to the pre-formulation of drugs in pharmaceutical developments.
In recent years, a large number of drugs have been industrialized, but almost 70% of them have low solubility in water, which limits their dissolution rate and, consequently, their bioavailability. Undoubtedly, it is a problem with far-reaching repercussions for the pharmaceutical industry, so the discovery of new technological tools for the hydrosolubilization of drugs that do not affect their physical–chemical and therapeutic properties will constitute an extraordinary achievement.
On the other hand, from a pharmacological point of view, the search for knowledge about the interaction mechanism and the different properties of drug-controlled release systems is currently of great importance in drug formulation, especially in relation to their efficacy therapy, as well as achieving the correct amount of active ingredient, the right time and the precise place of action.
This Special Issue is dedicated to the latest advances in solubilization and controlled release processes for poorly soluble drugs. We invite authors to submit original research or review articles on these topics, including the development of novel solubilization strategies, as well as innovative alternative methods to obtain new controlled-release pharmaceutical forms, suitable for a specific patient and the pathology to be treated, without forgetting the best form of administration to obtain the optimal efficacy and safety of the drugs.
Prof. Dr. María Ángeles Peña Fernández
Guest Editor
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Keywords
- drug formulation
- solubilization
- controlled release systems
- solubility
- poor water-soluble drugs
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