Nanotechnology for Drug and Gene Delivery
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 2796
Special Issue Editor
Special Issue Information
Dear Colleagues,
The advent of nanotechnology has led to the development of novel diagnostic and therapeutic strategies capable of changing how we treat cancer. The properties of nanotechnology can be harnessed to design diagnostic tools that enable the earlier detection and precise monitoring of patient responses to treatment, thus potentially enhancing patient outcomes. Nanotechnology also provides the means to target therapeutic agents both selectively and directly to neoplastic niches, thus enabling the safer delivery of radiotherapy, chemotherapy, and targeted therapies. The benefits of nanomaterials for cancer thus depend on their ability 1) to be easily functionalized an engineered, 2) to act as theranostic (i.e., diagnostic and therapeutic) platforms, 2) to passively accumulate at cancer sites through the EPR effect, 3) to be actively and selectively targeted to tumor cells while avoiding the side effects of traditional therapeutic modalities and 4) to overcome the traditional biological barriers, including the blood–brain barrier or the dense stroma of pancreatic cancer. In this Special Issue, we will explore the various applications of nanotechnology to cancer treatment. We will discuss the latest advances in 1) the application of nanotechnology in cancer detection and diagnosis and 2) nanotherapeutic solutions for cancer treatment including nano-enabled chemotherapy, radiotherapy, immune and targeted therapies, and gene delivery. We will also examine how nanotherapeutic approaches can be used to reprogram the tumor microenvironment to overcome drug resistance. Finally, we will review the current nanotechnology clinical trials.
Dr. Batoul Farran
Guest Editor
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Keywords
- nanoparticles
- drug and gene delivery
- cancer therapy
- chemotherapy
- radiotherapy
- immunotherapy
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