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Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The 20th Anniversary of Pharmaceuticals—Advances in Pharmacology

edited by

Gary J. Stephens

submission deadline 25 Dec 2024 | 7 articles | Viewed by 10233 | Submission Open

Keywords: behavioral pharmacology; cancer pharmacology; cardiovascular pharmacology; chronopharmacology; clinical pharmacology; immunopharmacology; molecular and biochemical pharmacology; neuropharmacology; pharmacoepidemiology; pharmacogenetics/pharmacogenomics; pharmacokinetics; systems pharmacology; toxicology; translational pharmacology/medicine; safety pharmacology

(This special issue belongs to the Section Pharmacology)

Kynurenine Pathway: A Novel Therapeutic Opportunity

edited by

Verónica Pérez de la Cruz

Tonali Blanco-Ayala

and

Daniela Ramírez-Ortega

submission deadline 25 Dec 2024 | 4 articles | Viewed by 8648 | Submission Open

(This special issue belongs to the Section Pharmacology)

Recent Advances in Psychopharmacology

edited by Roos Van Westrhenen and

Allan H. Young

submission deadline 25 Dec 2024 | 2 articles | Viewed by 5364 | Submission Open

Keywords: psychopharmaca; pharmacogenomics; pharmacogenetics; psychedelics; dementia drugs

(This special issue belongs to the Section Pharmacology)

Recent Advancements in the Development of Antiprotozoal Agents

edited by Francesco Saccoliti and Alessandro Giraudo

submission deadline 25 Dec 2024 | 2 articles | Viewed by 3491 | Submission Open

Keywords: antiprotozoal; drug discovery; chemotherapy; parasite; protozoa; mechanism of action of antiprotozoal agents

(This special issue belongs to the Section Medicinal Chemistry)

Purinergic Signaling: A New Pharmacological Target

edited by

Margarete Dulce Bagatini

submission deadline 25 Dec 2024 | 1 articles | Viewed by 1912 | Submission Open

Keywords: purinergic receptors; ectonucleotidases; nucleotides; nucleoside

(This special issue belongs to the Section Pharmacology)

Chirality: The Important Factor for Drug Discovery and Development

edited by

Li Li

Xuqin Li

and

Tao Ma

submission deadline 25 Dec 2024 | 1 articles | Viewed by 1828 | Submission Open

Keywords: chiral drugs; chiral natural products; chiral resolution; asymmetric synthesis; chiral spectroscopy; chiral impurities; atropisomerism; chiral analysis

(This special issue belongs to the Section Medicinal Chemistry)

20th Anniversary of Pharmaceuticals—Recent Advances in Metallodrug Design and Application

edited by Andrew Knight

submission deadline 25 Dec 2024 | 1 articles | Viewed by 1153 | Submission Open

Keywords: metallodrugs; metal complexes; transition metals; anti-viral; antibacterial; gold; silver; ruthenium; platinum; organometallic; drug discovery

(This special issue belongs to the Section Medicinal Chemistry)

Mitochondrial Protease ClpP in Antitumor-Drug Development: Recent Advances and Challenges

edited by

Maria Grazia Perrone

and

Morena Miciaccia

submission deadline 25 Dec 2024 | Viewed by 414 | Submission Open

Keywords: caseinolytic peptidase P (ClpP); mitochondrial protein quality control; small molecules as targeted drugs; cancer therapy; high-grade glioma; breast cancer; prostate adenocarcinoma; hematological malignancies; bladder cancer; ovarian cancer

(This special issue belongs to the Section Medicinal Chemistry)

The Pharmacology of Bisphosphonates: New Advances

edited by

Ewa Chmielewska

and

Paweł Kafarski

submission deadline 25 Dec 2024 | Viewed by 291 | Submission Open

Keywords: bisphosphonates; bisphosphonic acids; pharmacology of bisphosphonates; pharmacokinetics; pharmacodynamics; hypocalcemia; osteonecrosis; gastrointestinal disturbances; delivery systems of bisphosphonates; bisphosphonate prodrugs; osteoporosis; breast cancer; prostate cancer; hypercalcemia; antiresorptive properties; antibacterial properties; anti-cancer properties; antiparasitic activity; antiprotozoal properties; antiviral properties; effects of drugs on the metabolism and biomechanical properties of bone tissue; properties and effects of bisphosphonates in in vitro and/or in vivo experimental models of bone disorders; different bisphosphonates in an in vitro experimental model of bone disease

(This special issue belongs to the Section Pharmacology)

Recent Advances in Ocular Pharmacology

edited by

Lampros Lamprogiannis

and

Ioannis Tsinopoulos

submission deadline 25 Dec 2024 | Viewed by 183 | Submission Open

Keywords: ophthalmology; ocular diseases; drug delivery; drug targeting; controlled drug release; eye drops; biopolymers; nanomedicine; clinical applications; clinical trials

(This special issue belongs to the Section Pharmacology)

Discovering Novel Drugs from Plants

edited by

Yung-Chia Chen

submission deadline 25 Dec 2024 | Viewed by 157 | Submission Open

Keywords: natural products; drug discovery; bioactive compound; extraction; ethnopharmacology; preclinical test

(This special issue belongs to the Section Natural Products)

In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research, 2nd Edition

edited by

Xuyi Yue

and

Kiran Kumar Solingapuram Sai

submission deadline 30 Dec 2024 | 6 articles | Viewed by 11812 | Submission Open

Keywords: nuclear molecular imaging; drug development; in vivo application; biomarkers; nuclear precision medicine

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Biological Treatment for Rheumatic Diseases

edited by

Kornelia Kuźnik-Trocha

submission deadline 30 Dec 2024 | 1 articles | Viewed by 1291 | Submission Open

Keywords: biological drugs; new treatment strategies; antirheumatic agents; arthritis; rheumatic diseases

(This special issue belongs to the Section Biopharmaceuticals)

Computational Predictions of Molecules with Potential Therapeutic Effects

edited by

Whelton Miller

submission deadline 30 Dec 2024 | 1 articles | Viewed by 1074 | Submission Open

Keywords: biophysics; medicinal chemistry; drug discovery; molecular docking; molecular dynamics; structure-activity relationships; computer-aided drug design (CADD)

(This special issue belongs to the Section Medicinal Chemistry)

Recent Update of Gastroretentive and Intestinal Drug Delivery Systems

edited by Marival Bermejo,

Paloma Marina De la Torre-Iglesias

and Covadonga Álvarez-Álvarez

submission deadline 30 Dec 2024 | Viewed by 564 | Submission Open

Keywords: drug formulation; controlled release systems; colon-targeted release systems; biodegradable systems; gastroretentive drug delivery systems; intestinal drug delivery systems; chemical– physical characterization; in vitro/ex vivo/in vivo evaluation; drug gastroretention; pharmaceutical development

(This special issue belongs to the Section Pharmaceutical Technology)

Sex Differences in Pharmaceutical Practice

edited by

Silvia De Francia

and

Sarah Allegra

submission deadline 31 Dec 2024 | 6 articles | Viewed by 14951 | Submission Open

Keywords: sex; differences; drugs; kinetics; dynamics; preclinical; clinical; research

(This special issue belongs to the Section Medicinal Chemistry)

Plant-Based Extracts and the Therapeutic Potential of Bioactive Compounds

edited by

Grażyna Zgórka

submission deadline 31 Dec 2024 | 7 articles | Viewed by 13900 | Submission Open

Keywords: plant extracts; herbal medicinal products; standardization; phytochemical profiling; bioactive plant compounds; therapeutic effects

(This special issue belongs to the Section Natural Products)

The 20th Anniversary of Pharmaceuticals—Advances in Natural Products

edited by

Daniela De Vita

and

Marianna Carbone

submission deadline 31 Dec 2024 | 7 articles | Viewed by 13800 | Submission Open

(This special issue belongs to the Section Natural Products)

Natural Compounds as Potential Anticancer, Anti-inflammatory and Antioxidant Agents in Medicine

edited by

Justyna Stefanowicz-Hajduk

submission deadline 31 Dec 2024 | 1 articles | Viewed by 1899 | Submission Open

Keywords: phytochemistry of plant extracts; plant secondary metabolites; clinical applications; in vitro; in vivo; ex vivo studies; cell and tissue cultures

(This special issue belongs to the Section Natural Products)

Recent Advances in Psychiatric Medications

edited by

Przemyslaw Waszak

and Paweł Zagożdżon

submission deadline 31 Dec 2024 | 1 articles | Viewed by 1891 | Submission Open

Keywords: mental health treatment; psychopharmacology; antidepressants; antipsychotics; side effects; safety profiles; treatment resistance; adherence issues

(This special issue belongs to the Section Medicinal Chemistry)

Structural and Computationally Driven Molecule Design in Drug Discovery: 2nd Edition

edited by

Halil İbrahim Ciftci

Belgin Sever

and

Hasan Demirci

submission deadline 31 Dec 2024 | 2 articles | Viewed by 1842 | Submission Open

Keywords: structural dynamics studies; computer-aided drug design; molecular dynamics simulations; molecular docking; virtual screening; QSAR; in silico ADMET; artificial intelligence (AI) techniques

(This special issue belongs to the Section Medicinal Chemistry)

Calcium Channels as Therapeutic Targets

edited by

Gary J. Stephens

David Adams

and

Hussein N. Rubaiy

submission deadline 31 Dec 2024 | 2 articles | Viewed by 1405 | Submission Open

Keywords: voltage-gated Ca2+ channels; TRP channels; Ca2+-permeable TRP and ASIC channels; STIM/orai channels; Ca2+ channel structure and function; Ca2+ channel toxins; Ca2+ channelopathies; neuropharmacology; pain; epilepsy; neurodegenerative and neuropsychiatric disorders

(This special issue belongs to the Section Pharmacology)

Drug Discovery of Antiprotozoal Agents 2024

edited by

Francisco Jaime Bezerra Mendonça Júnior

and

Pascal Marchand

submission deadline 31 Dec 2024 | 1 articles | Viewed by 1340 | Submission Open

Keywords: antiprotozoal agents; drug discovery; medicinal chemistry; natural products; in vitro and in vivo studies; ADMET; computer-aided drug design; chemoinformatics; molecular docking; virtual screening

(This special issue belongs to the Section Medicinal Chemistry)

Natural Products in Drug Discovery in the 21st Century: Challenges and Opportunities

edited by

Noelia Duarte

submission deadline 31 Dec 2024 | Viewed by 443 | Submission Open

Keywords: natural products; bioactive natural compounds; marine drugs; medicinal plants; in vitro and in vivo biological activity; pharmacological activity; drug discovery; medicinal and technological applications; medicinal chemistry

(This special issue belongs to the Section Natural Products)

Biomarkers and Therapeutic Targets for Melanoma

edited by

Italia Falcone

submission deadline 31 Dec 2024 | Viewed by 300 | Submission Open

Keywords: melanoma; tumor microenvironment; tumor metabolism; omics technologies; precision medicine; biomarkers; melanoma treatment approaches; drug resistance

(This special issue belongs to the Section Pharmacology)

Discovery and Development of Novel Analgesics

edited by Ethel Antunes Wilhelm and Angélica Schiavom dos Reis

submission deadline 31 Dec 2024 | Viewed by 278 | Submission Open

Keywords: analgesics; pain management; pain biology; pharmacological potential; preclinical models; therapeutic development; synthetic compounds; natural compounds; neuropathic pain; chemotherapy-induced neuropathy

(This special issue belongs to the Section Medicinal Chemistry)

Computational Methods in Drug Development

edited by

Yunjie Zhao

submission deadline 31 Dec 2024 | Viewed by 247 | Submission Open

Keywords: computational modeling; DNA/RNA and protein; drug discovery and design; systems biology; channels and membranes; biomedical data analysis; artificial intelligence; molecule docking and scoring

(This special issue belongs to the Section Medicinal Chemistry)

Therapeutic Potential of Aldehyde Dehydrogenases

edited by

Ilias Tsochantaridis

and

Georgia-Persephoni Voulgaridou

submission deadline 31 Dec 2024 | Viewed by 226 | Submission Open

Keywords: ALDH; cancer; cancer stem cells; diabetes; Parkinson’ s disease; Alzheimer’ s disease; ALDH inhibitors; ALDH signaling; CSC-based therapeutics; therapeutic strategies

(This special issue belongs to the Section Medicinal Chemistry)

Using In Vitro and Ex Vivo Models to Evaluate Strategies for Drug Delivery Improvement

edited by

Dewald Steyn

and

Sias Hamman

submission deadline 31 Dec 2024 | Viewed by 211 | Submission Open

Keywords: bioenhancers; epithelial tissue; formulation approaches; in vitro models; ex vivo models; nanoparticulate systems; permeation enhancement; smart delivery systems; solubility enhancement

(This special issue belongs to the Section Pharmaceutical Technology)

Current Pharmacotherapy for Viral Hepatitis

edited by

Robert Flisiak

submission deadline 31 Dec 2024 | Viewed by 197 | Submission Open

Keywords: liver; viral hepatitis; HBV; HCV; HDV; therapy

(This special issue belongs to the Section Pharmacology)

Glycomimetics and Glycoconjugates in Drug Discovery, 2nd Edition

edited by

Nuno Xavier

submission deadline 31 Dec 2024 | Viewed by 166 | Submission Open

Keywords: glycoconjugates; glycomimetics; carbohydrate– protein interactions; carbohydrate-acting enzymes; medicinal glycochemistry; drug design; drug discovery

(This special issue belongs to the Section Biopharmaceuticals)

Pharmaceutical Formulation Characterization Design

edited by

Tamás Sovány

and

Katalin Kristó

submission deadline 5 Jan 2025 | 4 articles | Viewed by 3928 | Submission Open

Keywords: quality by design; factorial design; design space; solid dosage forms; risk assessment; critical process parameters; quality target product profile

(This special issue belongs to the Section Pharmaceutical Technology)

Pharmaceutical Application of Essential Oils

edited by

Paweł Kwiatkowski

submission deadline 12 Jan 2025 | Viewed by 195 | Submission Open

Keywords: essential oils; bacteria; fungi; alternative therapy; antimicrobial resistance; mechanism of action

(This special issue belongs to the Section Natural Products)

Applications of Liquid Chromatography Coupled with Mass Spectrometry (LC-MS/MS) in Drug Analysis

edited by Isabela Tarcomnicu and

Valentina Anuta

submission deadline 15 Jan 2025 | 6 articles | Viewed by 9067 | Submission Open

Keywords: pharmaceutical analysis; bioanalysis; liquid chromatography; mass spectrometry; impurities; bioavailability; metabolism; environmental fate

(This special issue belongs to the Section Pharmaceutical Technology)

Biological and Pharmacological Research on Indole-3-Carbinol (I3C) and Its Derivatives

edited by

Federica Centofanti

submission deadline 15 Jan 2025 | 2 articles | Viewed by 1752 | Submission Open

Keywords: indole-3-carbinol; natural and synthetic derivatives of I3C; synthetic procedures; biosynthetic processes; in vitro; in vivo and clinical studies; mechanism of action; biological properties; pharmacological properties; potential therapeutic applications in health and disease

(This special issue belongs to the Section Pharmacology)

Therapeutic Potential of Chalcone Derivatives

edited by Hélcio Silva Dos Santos

submission deadline 15 Jan 2025 | 1 articles | Viewed by 811 | Submission Open

Keywords: chalcones; pharmacological potential; structural characterization; bioactivity; in silico study; cytotoxicity; quantum chemical calculations; ecapsulation

(This special issue belongs to the Section Pharmacology)

Exploring the Anticancer and Immunomodulatory Mechanisms of Phytochemicals and Natural Bioactive Compounds

edited by Suyun Lyu

submission deadline 15 Jan 2025 | Viewed by 287 | Submission Open

Keywords: natural products; phytochemicals; anticancer; immunomodulation; bioactive compounds

(This special issue belongs to the Section Pharmacology)

Emerging Trends in Inhaled Drug Delivery

edited by

Nitesh K. Kunda

submission deadline 20 Jan 2025 | 2 articles | Viewed by 3403 | Submission Open

Keywords: inhaled drug delivery; quality-by-design; nanoparticles in inhalation; pulmonary vaccine delivery

(This special issue belongs to the Section Pharmaceutical Technology)

Biomedical Properties, Developments and Therapeutic Potential of Sesquiterpenoid Lactones and Natural Compounds

edited by

Normand Garcia-Hernandez

Rosa Ordoñez Razo

and Israel Ramírez-Sánchez

submission deadline 20 Jan 2025 | 1 articles | Viewed by 2400 | Submission Open

Keywords: therapeutic potential; natural compounds; biological activity; traditional medicine; sesquiterpene lactone; pharmacological activities; terpenoids; flavonoids

(This special issue belongs to the Section Natural Products)

Pharmacotherapy of Gastric Cancer

edited by

Gabriel Samasca

submission deadline 20 Jan 2025 | 1 articles | Viewed by 1409 | Submission Open

Keywords: chemotherapy; immunotherapy; peritoneal carcinomatosis; microbiota; pharmaceutical solutions

(This special issue belongs to the Section Pharmacology)

Self-Assembling Nanostructures for Cancer Therapy

edited by

André Moreni Lopes

submission deadline 20 Jan 2025 | 1 articles | Viewed by 1041 | Submission Open

Keywords: drug delivery systems; polymeric micelles; polymeric vesicles (polymersomes); surfactants; amphiphilic copolymers; stimuli-responsive polymers; cancer therapy; drugs; biopharmaceuticals; dual delivery

(This special issue belongs to the Section Pharmaceutical Technology)

Chemoinformatics and Drug Design, 2nd Edition

edited by Weifan Zheng

submission deadline 20 Jan 2025 | 1 articles | Viewed by 795 | Submission Open

Keywords: artificial intelligence (AI); machine learning (ML); representation learning; cheminformatics; drug discovery; drug repurposing; biological activity prediction; drug– target– disease interactions

(This special issue belongs to the Section Medicinal Chemistry)

Emerging Trends in Liquid Chromatography and Mass Spectrometry-Based Analyses of Pharmaceuticals

edited by

Martina Bortolami

Paola Di Matteo

and

Rita Petrucci

submission deadline 20 Jan 2025 | Viewed by 686 | Submission Open

Keywords: pharmacokinetic analyses; drug metabolites; drug delivery systems; biological matrices; environmental samples; environmental monitoring

(This special issue belongs to the Section Medicinal Chemistry)

Classical and Quantum Molecular Simulations in Drug Design

edited by

Osvaldo Andrade Santos-Filho

submission deadline 20 Jan 2025 | 1 articles | Viewed by 589 | Submission Open

Keywords: molecular dynamics simulations; monte carlo simulations; docking simulations; free energy calculations; QM/MM modeling

(This special issue belongs to the Section Medicinal Chemistry)

Novel Therapeutic Targets and Approaches for the Treatment for Alzheimer's Disease

edited by

Marta Rusek

submission deadline 20 Jan 2025 | Viewed by 380 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer's disease; molecular mechanism; drug delivery; drug development; potential therapeutic; advanced therapies; disease-modifying therapy; personalized therapy; clinical trials

(This special issue belongs to the Section Pharmacology)

Chitosan Based Novel Pharmaceutical Dosage Forms and Drug Delivery Systems

edited by

Ljiljana Djekic

and

Anđelija M. Malenović

submission deadline 24 Jan 2025 | 6 articles | Viewed by 20892 | Submission Open

Keywords: chitosan; chitosan derivatives; chitosan grafted copolymers; chitosan-ligand conjugates; chitosan/polyanions polyelectrolyte complexes; formulation development; drug delivery systems; controlled drug release; drug targeting

(This special issue belongs to the Section Pharmaceutical Technology)

20th Anniversary of Pharmaceuticals—Green Techniques for Organic and Organometallic/Coordination Synthesis and Medicinal Chemistry

edited by

Mafalda Cruz Sarraguca

and

Clara Gomes

submission deadline 24 Jan 2025 | 4 articles | Viewed by 16975 | Submission Open

Keywords: green chemistry; medicinal chemistry; organometallic synthesis; coordination synthesis; organic synthesis

(This special issue belongs to the Section Medicinal Chemistry)

Recent Advances in Natural Product Based Nanostructured Systems

edited by

Luís Alexandre Muehlmann

and

João Paulo Longo

submission deadline 24 Jan 2025 | 7 articles | Viewed by 13456 | Submission Open

(This special issue belongs to the Section Natural Products)

Antioxidants in the Processes of Retarding Ageing

edited by

Mateusz Mołoń

and

Sabina Galiniak

submission deadline 24 Jan 2025 | 2 articles | Viewed by 5060 | Submission Open

Keywords: aging; anti-aging medicine; antioxidant; model organisms; oxidative stress markers; reactive oxygen species

(This special issue belongs to the Section Medicinal Chemistry)

Advancements and Challenges of Intrapleural and Peritoneal Drug Delivery

edited by

Veria Khosrawipour

Agata Mikolajczyk-Martinez

and

Tanja Khosrawipour

submission deadline 24 Jan 2025 | 2 articles | Viewed by 4480 | Submission Open

Keywords: peritoneal and pleural malignancies; intraperitoneal and pleural drug delivery; peritoneal dialyses; peritonitis; pleuritis; hyperthermic intraperitoneal chemotherapy (HIPEC); surface applications; colorectal cancer; ovarian cancer

(This special issue belongs to the Section Pharmaceutical Technology)

Displaying special issue 51-100 on page 2 of 8.

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