Novel Carriers for Drug Delivery and Brain Disease Treatment across the Blood-Brain Barrier

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 249

Special Issue Editors


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Guest Editor
HUN-REN Biological Research Centre, Institute of Biophysics, Szeged, Hungary
Interests: blood-brain barrier; blood-brain barrier dysfunction; brain endothelial protection; targeted drug delivery; targeted nanoparticle; BBB transporters; BBB transcytosis; organ-on-chip models
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA
Interests: neuroscience; blood-brain-barrier; drug delivery; antibody delivery; target discovery; transport proteins; brain diseases

Special Issue Information

Dear Colleagues,

We are excited to announce the initiation of a thought-provoking Special Issue entitled “Novel Carriers for Drug Delivery and Brain Disease Treatment across the Blood–Brain Barrier”. The blood–brain barrier (BBB) poses a formidable challenge in drug delivery to the central nervous system (CNS), necessitating innovative approaches to overcome its restrictive nature. Our focus is shedding light on the latest advancements in BBB drug delivery methodologies and their applications in treating a spectrum of CNS disorders, including neurodegenerative diseases, brain cancers, and genetic disorders. In this Special Issue, we aim to provide a comprehensive platform to showcase recent breakthroughs and emerging trends in BBB drug delivery. We invite contributions spanning a wide array of topics, including but not limited to carrier-mediated transport, receptor-mediated transcytosis, lipid-raft-mediated transcytosis, and other innovative approaches. Manuscripts exploring the design, synthesis, characterization, and preclinical/clinical evaluation of novel drug carriers for BBB penetration are highly encouraged.

Through collaborative efforts and interdisciplinary insights, we aim to translate cutting-edge research into transformative therapies, ultimately reshaping the landscape of brain disease treatment. We look forward to your valuable contributions, which will undoubtedly enrich the discourse in this field toward new advancements and innovation.

Prof. Dr. Mária A. Deli
Dr. Ana R. Santa-Maria
Guest Editors

Manuscript Submission Information

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Keywords

  • novel carriers
  • drug delivery
  • blood–brain barrier (BBB)
  • carrier technologies
  • transformative therapies
  • neurological disorders

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Published Papers

This special issue is now open for submission.
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