Functionalized Nanoparticles in Cancer Therapeutics, 2nd Edition
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 20 February 2025 | Viewed by 7471
Special Issue Editors
Interests: nanoparticles; liposomes; solubility improvement; chemotherapeutic delivery
Special Issues, Collections and Topics in MDPI journals
Interests: drug resistance; chemotherapy failure; drug–drug interaction; anticancer drug discovery; novel mechanisms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is a leading cause of death, accounting for millions of lives lost worldwide. Drug discovery and development efforts have provided highly potent chemotherapeutic drug molecules for the treatment of various cancers. However, many cancer mortalities are due to high systemic exposures from conventional chemotherapeutic drugs to various organs and inadequate delivery to the tumor sites. Targeted delivery of drugs, via functional nanomedicines to cancer tumors in a “magic bullet” approach, selectively kills the tumor cells without harming the benign cells. Current clinical practice for cancer treatment is based on many functional nanomedicines for tumor targeting with minimal exposure to “normal” cells, thus avoiding toxicity to the patient.
This Special Issue covers the following nanomedicines:
- Protein, polymer, and lipid-based nanomedicines with multi functionalities such as targeted moieties, triggered stimuli responses, immunoevasion (pegylation), prolonged release, and protection of the drug from degradation;
- Inorganic nanomedicines with unique electromagnetic properties for tumor site-specific delivery and diagnostic and imaging capabilities;
- Nanomedicines prepared with various functional biomaterials with unique transport properties for tumor targeting via enhanced permeability and retention (EPR) effect.
Prof. Dr. R. Jayachandra Babu
Dr. Amit K. Tiwari
Guest Editors
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Keywords
- liposomes
- polymeric nanoparticles
- dendrimer-based nanoparticles
- micellar nanoparticles
- inorganic nanoparticles
- small interfering RNA-based nanoparticles
- protein-based nanoparticles
- functional nanomaterials
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