Application of Phytochemicals in Innovative Drug Delivery Systems and Formulations
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 142
Special Issue Editors
Interests: drug delivery systems; nanocarriers; targeting; inflammation; cancer; biomimetic vesicles
Special Issues, Collections and Topics in MDPI journals
Interests: controlled drug release; hydrogels; drug targeting; biocompatible polymers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The impelling need for novel and more effective compounds for the treatment of several pathological conditions like cancer, inflammation, and infections has driven research towards alternative sources, especially plants; currently, about 60% of the commonly used anticancer drugs were obtained from natural sources, either inspired by traditional medicine or revealed by experimental findings. Medicinal plants are rich in diverse phytochemicals, such as flavonoids, terpenoids, alkaloids, saponins, lignins, coumarines, stilbenes, and taxanes. Despite their beneficial potential, the therapeutic use of phytochemicals is frequently hampered by bioavailability issues, due to poor water solubility, a high metabolization rate, and low chemical stability, issues that may be overcome by including the phytochemical in a nano- or microformulation such as, for instance, lipid- or polymer-based nano- and microparticles, micelles and nanosponges. Furthermore, nanosizing techniques, leading to the formation of nanocrystals, have been explored to enhance the pharmacokinetics of phytochemicals.
We are pleased to invite academics and pharmaceutical researchers to bring their new insights into the development of innovative drug delivery systems and formulations for the therapeutic application of phytochemicals.
This Special Issue aims to collect the most recent and innovative formulations able to efficiently deliver plant-derived actives, enhancing their pharmacokinetics, therapeutic efficacy, and stability, with a special focus on the technological aspects underlying the development of such systems. Moreover, manuscripts regarding the development of innovative formulations for using phytochemicals in the treatment of animals as well as plant diseases will be considered for publication.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Microparticles;
- Nanomedicine;
- Pharmaceutical formulation;
- Phytochemicals;
- Phytotherapy;
- Cancer;
- Inflammation.
We look forward to receiving your contributions.
Dr. Giorgia Ailuno
Dr. Sara Baldassari
Guest Editors
Manuscript Submission Information
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Keywords
- microparticles
- nanoparticles
- drug delivery systems
- cancer
- inflammation
- phytochemicals
- phytotherapy
- medicinal plants
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