Peptide-Based and Hybrid Carriers for Nucleic Acids Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Gene and Cell Therapy".
Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 2025
Special Issue Editors
Interests: gene therapy; nucleic acids delivery; gene silencing; gene expression; peptide-based carriers; receptor-mediated delivery; transfection; genetic testing; spinal muscular atrophy; uterine leiomyoma; endometriosis; duchenne muscular dystrophy; cellular models; animal models
2. Institute of Chemistry, Saint-Petersburg State University, 199034 St. Petersburg, Russia
Interests: bio-inspired polymers; biodegradable polymers; biopolymers; ring-opening polymerization; free radical polymerization; controlled radical polymerization; copolymers; amphiphilic copolymers; self-assembly; polymer nanoparticles; macroporous polymer materials; biocomposites; polymer scaffolds; delivery of small molecules; gene delivery
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Special Issue Information
Dear Colleagues,
As Guest Editors, we are pleased to announce the launch of a Special Issue of Pharmaceutics titled “Peptide-Based and Hybrid Carriers for Nucleic Acid Delivery”. Nanoparticles formed by nucleic acids and peptide-based carriers can be a versatile tool for delivery of various genetic constructs (pDNA, siRNA, miRNA, mRNA, etc.) to cells in favor of gene therapy of inherited and acquired diseases. Their advantages include biodegradability and easiness of modification of the structure and amino acid composition. Natural (ligands, various intra- and extracellular signals, etc.) and synthetic (poly)peptide sequences can be used as part of peptide-based and hybrid carriers to overcome the barriers to the transport of therapeutic genetic material into the cells.
We invite you to contribute to the new Special Issue with the aim to gather and feature the latest advances, perspectives, and trends in the development of poly- and oligopeptide and peptide-containing hybrid carriers for the delivery of therapeutic nucleic acids. Both feature articles and literature reviews are acceptable for publication.
Dr. Anton Kiselev
Dr. Korzhikova-Vlakh Evgenia
Guest Editors
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Keywords
- nucleic acids
- gene therapy
- nucleic acids delivery
- gene drugs
- gene delivery
- (poly)peptide delivery systems
- peptide-containing hybrid delivery systems
- design of (poly)peptide carriers
- (poly)peptide/nucleic acid complexes
- gene silencing
- transfection
- gene expression
- peptide ligands
- receptor-mediated delivery
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