The Role of Nutritional Attitudes on Mental Diseases

A special issue of Psychiatry International (ISSN 2673-5318).

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 9354

Special Issue Editors


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Guest Editor
Unit of Human Nutrition, Laboratory of Nutrition and Public Health, Department of Food Science and Nutrition, University of the Aegean, GR-81400 Lemnos, Greece
Interests: nutrition and health; functional foods; bioactive compounds; bioactivity and bioavailability; phytochemicals and chronic diseases
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Guest Editor
1st Psychiatric Department, Eginition Hospital, Medical School, National and Kapodistrian University of Athens, 10679 Athens, Greece
Interests: eating disorders; borderline personality disorder; cognitive and dialectical behavioral therapy

Special Issue Information

Dear Colleagues,

Nutrition is considered as an external factor that may affect the appearance and progression of Mental Diseases. Scientific evidence support that several nutrients may affect the production of hormones that are involved in the progression of mental diseases, as serotonin and dopamine, while specific dietary habits may be correlated with the pathophysiology of such diseases.

This Special Issue focuses on the further investigation of the possible role of nutritional attitudes such as orthorectic and restrictive behavior, dietary standards, as Mediterranean diet, and specific nutrients and bio-functional compounds (macronutrients, micronutrients, phytochemicals etc) on the prevention or management of mental diseases, based mainly on clinical and epidemiological evidence.

We welcome papers reporting latest evidence-based results of the effect of nutritional habits and specific nutrients, bioactive compounds and functional foods on pathophysiology mechanisms, indexes and biomarkers of mental diseases, such as anxiety, depression, anorexia and bulimia nervosa, personality disorders etc. Animal experiments, clinical trials and epidemiological studies, but also in vitro studies, meta-analyses and review articles are welcome. Studies concerning the possible role of nutrients and bio-functional compounds on the expression of genes that are associated with mental diseases are especially welcome.

Dr. Antonios E. Koutelidakis
Dr. Fragiskos Gonidakis
Guest Editors

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Keywords

  • nutrition
  • dietary attitudes
  • bio-functional compounds
  • mental diseases
  • anxiety
  • depression
  • bulimia and anorexia nervosa

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Published Papers (3 papers)

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Research

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16 pages, 1146 KiB  
Article
Ghrelin and Obestatin in Adolescent Patients with Anorexia Nervosa: Is There an Association with Disordered Eating, Depression, and Obsessive-Compulsive Symptoms?
by Agata Dutkiewicz, Marta Tyszkiewicz-Nwafor, Karolina Bilska, Elżbieta Paszyńska, Magdalena Roszak, Weronika Zwolińska, Natalia Pytlińska, Agnieszka Słopień and Monika Dmitrzak-Węglarz
Psychiatry Int. 2022, 3(3), 248-263; https://doi.org/10.3390/psychiatryint3030020 - 19 Sep 2022
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Abstract
Anorexia nervosa (AN) is an eating disorder characterized by restrictive eating and significant weight loss. In the course of AN, changes are observed in appetite regulation, including orexigenic ghrelin and potentially anorexigenic obestatin. The study aimed to determine if any changes in serum [...] Read more.
Anorexia nervosa (AN) is an eating disorder characterized by restrictive eating and significant weight loss. In the course of AN, changes are observed in appetite regulation, including orexigenic ghrelin and potentially anorexigenic obestatin. The study aimed to determine if any changes in serum ghrelin and obestatin levels during treatment of AN are observed, while investigating the correlations between these peptides and the severity of disturbed eating attitudes, depression, and anxiety. Thirty adolescent inpatients with AN (examined twice: before hospitalization treatment AN-BT and after treatment AN-AT) and thirty healthy age- and height-matched girls (CG) participated in the study. Anthropometric, serum ghrelin and obestatin concentrations and psychometric evaluations (Eating Attitudes Test 26 Item-EAT-26, Beck Depression Inventory-BDI, Hamilton Depression Rating Scale-HDRS, and Yale Brown Obsessive-Compulsive Scale-Y-BOCS) were performed. The study revealed significantly higher ghrelin and obestatin levels in AN-BT than in AN-AT. A trend toward lower levels during treatment provided partial normalizations. Analyzing correlations in the AN-BT vs. CG group, correlations of peptides with EAT-26, BDI, and HDRS scores were detected. These results suggest a potential role for ghrelin and obestatin in the context of defense mechanisms regulating appetite and body weight in the course of AN and in terms of psychopathological changes co-occurring with this eating disorder. Full article
(This article belongs to the Special Issue The Role of Nutritional Attitudes on Mental Diseases)
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16 pages, 329 KiB  
Article
Investigation of Loneliness and Social Support in Patients with Eating Disorders: A Case-Control Study
by Eleni Makri, Ioannis Michopoulos and Fragiskos Gonidakis
Psychiatry Int. 2022, 3(2), 142-157; https://doi.org/10.3390/psychiatryint3020012 - 24 Apr 2022
Cited by 8 | Viewed by 4794
Abstract
Loneliness and, to a lesser degree, social support are considered under-researched topics in the literature on eating disorders (ED). This study attempted to expand the relevant body of research by examining loneliness in combination with social support in ED patients and in healthy [...] Read more.
Loneliness and, to a lesser degree, social support are considered under-researched topics in the literature on eating disorders (ED). This study attempted to expand the relevant body of research by examining loneliness in combination with social support in ED patients and in healthy controls (HC). Binge-eating problems, emotional eating, resilience, anxiety, and depression symptoms were also assessed. Thirty-two patients with ED and twenty-nine HC completed the following measures: UCLA Loneliness Scale, Social Support Questionnaire—Short Form, Binge Eating Scale, Emotional Eating Scale, Connor–Davidson Resilience Scale, Hospital Anxiety and Depression Scale, and the Eating Disorder Examination Questionnaire. Eating-disorder patients showed higher levels of loneliness and lower levels of social support—both in terms of perceived availability and satisfaction—than HC. Anorexia nervosa (AN), bulimia nervosa (BN), and binge-eating disorder (BED) subgroups did not differ significantly on either of these variables. In ED patients, loneliness was only correlated with Social Support Satisfaction (negatively) and depressive symptomatology (positively). Patients with ED appear to be lonelier and less satisfied with their social support compared to HC. We found similar levels of loneliness and social support between AN, BN, and BED sufferers. Decreased social support satisfaction and elevated symptoms of depression could account for ED patients’ high levels of loneliness. Full article
(This article belongs to the Special Issue The Role of Nutritional Attitudes on Mental Diseases)

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15 pages, 5500 KiB  
Systematic Review
Efficacy of Naltrexone/Bupropion in Treatment of Binge Eating: A Systematic Review and Meta-Analysis
by Mostafa Hossam-Eldin Moawad, Mohammed Ahmed Sadeq, Abdallah Abbas, Reem Mohamed Farouk Ghorab, Ibrahim Serag, Mohamed Hendawy and Muhammad Alkasaby
Psychiatry Int. 2024, 5(3), 323-337; https://doi.org/10.3390/psychiatryint5030022 - 2 Jul 2024
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Abstract
Background: As the most widespread eating disorder in the world now, binge eating disorder (BED) is a mental condition characterized by recurrent periods of excessive food consumption and an inability to regulate one’s portion sizes. The utilization of a bupropion–naltrexone (NB) combination has [...] Read more.
Background: As the most widespread eating disorder in the world now, binge eating disorder (BED) is a mental condition characterized by recurrent periods of excessive food consumption and an inability to regulate one’s portion sizes. The utilization of a bupropion–naltrexone (NB) combination has been suggested as a potential therapeutic approach for BED. Assessing the effectiveness of NB in the treatment of BED and its accompanying obesity is the purpose of this research. Methods: A comprehensive search was conducted in order to obtain any pertinent articles. PubMed, Scopus, Web of Science, and Cochrane Clinical Trials were consulted against in the databases that were searched. In our final meta-analysis, we incorporated interventional or observational studies that documented the effects of NB therapy for binge eating in adults. We also examined the difference in the mean change between the NB and placebo groups, as well as the disparity in outcomes before and after treatment. Results: This study shows that the use of an NB combination is associated with a statistically significant reduction in the weight, BMI, and Binge Eating Scale (BES) of the patients compared to their weight before treatment with MD: −8.52 (95% CI: −10.01–−6.94, p < 0.00001), MD: −4.95 (95%CI: −9.72–−0.17, p = 0.04), and MD: −7.66 (95%CI: −14.36–0.96, p = 0.02), respectively. The absolute mean change was statistically significantly higher in the drug combination group compared to the placebo group. Conclusions: NB showed efficacy in the improvement of the weight and psychiatric symptoms associated with BED and this provides a promising treatment option. Full article
(This article belongs to the Special Issue The Role of Nutritional Attitudes on Mental Diseases)
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