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Sustainable Bio-Based Nanomaterials for Various Biological Applications
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Sustainable Bio-Based Nanomaterials for Various Biological Applications

A special issue of Sustainability (ISSN 2071-1050). This special issue belongs to the section "Sustainable Materials".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 15112

Special Issue Editors

Dr. Sekar Vijayakumar

E-Mail Website
Guest Editor
Marine College, Shandong University, Weihai 264209, China
Interests: nanobiotechnology; nanomedicine; nanobiology; biomaterials; biopolymers; drug delivery; microbial biofilm; cancer; natural polysaccharides; biosynthesis; phytomedicine; aquaculture; ecotoxicolog
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Roberto Christ Vianna Santos

E-Mail Website
Guest Editor
Laboratory of Oral Microbiology Research, Microbiology and parasitology Department, Universidade Federal de Santa Maria, Santa Maria 97105-900, RS, Brazil
Interests: biofilms; antimicrobial resistance; natural products; nanotechnology; bacteriology
Special Issues, Collections and Topics in MDPI journals
Dr. Ramanathan Srinivasan

E-Mail Website
Guest Editor
Natural Product Research Center of Excellence, Prince of Songkla University, Chang Wat Songkhla 90110, Thailand
Interests: animal studies; antibiotic resistance; aquatic pathogens; biofilm; combinational approaches; infectious diseases; molecular genomics; molecular proteomics; nanotechnology; natural products; nosocomial pathogens; quorum sensing

Special Issue Information

Dear Colleagues,

Currently, there is a significant increase in the demand for sustainable materials. The development of this kind of material is of great importance to ensure the best management of natural resources such that they do not become depleted, thereby ensuring that it is possible to meet the needs of present and future generations. Bio-nanotechnology is a novel field of nanotechnology that combines biological principles with physical and chemical procedures to produce nanomaterials. This approach may be applied to the development of nanomaterials that can be used in various applications in the biological sciences.

Bio-based nanomaterials are products composed primarily of natural substances/compounds generated from living stuff (microbes, plants, and animals), which may occur naturally or be synthesized, or products made using biomass-based methods. Bio-based nanomaterial synthesis is both environmentally friendly and cost-effective, and it can be readily scaled up for large-scale manufacturing. As a result, in the field of biological sciences, the synthesis of bio-based nanomaterials has received much interest. Sustainable bio-based methods will not only protect us from chemical toxicity but also allow us to develop more biocompatible nanomaterials.

With this Special Issue, we aim to collect a series of high-quality research and review manuscripts covering promising, recent, and novel research trends in sustainable bio-based nanomaterials with great possibilities regarding biological applications such as in antimicrobials, antibiofilm, anti-quorum sensing, antiviral, anticancer, antiparasitic, mosquito control, food packaging, environmental remediation, etc.

In addition to above, we also welcome various research contributions related to other biological applications of bio-based nanomaterials.

Dr. Sekar Vijayakumar
Prof. Dr. Roberto Christ Vianna Santos
Dr. Ramanathan Srinivasan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sustainability is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bio-based nanomaterials
  • biocompatible
  • biological applications
  • nanotechnology
  • natural compounds
  • natural substances
  • biopolymers
  • polysaccharides
  • sustainable

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Published Papers (5 papers)

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Research

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20 pages, 4907 KiB  
Article
Optimization, Characterization, and Biological Applications of Silver Nanoparticles Synthesized Using Essential Oil of Aerial Part of Laggera tomentosa
by Yilma Hunde Gonfa, Abiy Abebe Gelagle, Bekele Hailegnaw, Samuel Abicho Kabeto, Getachew Adam Workeneh, Fekade Beshah Tessema, Mesfin Getachew Tadesse, Saikh M. Wabaidur, Kholood A. Dahlous, Sami Abou Fayssal, Pankaj Kumar, Bashir Adelodun, Archana Bachheti and Rakesh Kumar Bachheti
Sustainability 2023, 15(1), 797; https://doi.org/10.3390/su15010797 - 1 Jan 2023
Cited by 9 | Viewed by 3184
Abstract
Biological synthesis of silver nanoparticles (AgNPs) is a green, simple, cost-effective, time-efficient, and single-step method. This study mainly focused on the synthesis of silver nanoparticles (AgNPs) using essential oil of Laggera tomentosa (LTEO) and investigates their potential applications. Ultraviolet-Visible (UV-Vis) result showed the [...] Read more.
Biological synthesis of silver nanoparticles (AgNPs) is a green, simple, cost-effective, time-efficient, and single-step method. This study mainly focused on the synthesis of silver nanoparticles (AgNPs) using essential oil of Laggera tomentosa (LTEO) and investigates their potential applications. Ultraviolet-Visible (UV-Vis) result showed the characteristic Surface Plasmon Resonance (SPR) peak of LTEO-AgNPs at 420 nm. Fourier transform infrared (FT-IR) spectroscopy indicated the functional groups present in LTEO and LTEO-AgNPs. Scanning electron microscope (SEM) image depicted the synthesized AgNPs mainly has spherical shapes with average nanoparticles size 89.59 ± 5.14 nm. Energy dispersive X-ray (EDX) peak at 3.0 keV showed the presence of Ag element in LTEO-AgNPs. The X-ray diffraction (XRD) peaks at 38°, 44° and 67° are assigned to (111), (200), and (220), respectively which displays the crystal nature of LTEO-AgNPs. The average particle size and zeta potential of LTEO-AgNPs were determined as 94.98 nm and −49.6 mV, respectively. LTEO-AgNPs were stable for six months against aggregation at room temperature. LTEO-AgNPs solutions exhibited potential activities for the treatment of some pathogenic bacteria species, agricultural productivity growth, determination of metallic ions, and catalytic reduction. This study is the first work to report nanoparticles synthesis using L. tomentosa extracts and evaluate their potential applications. Full article
(This article belongs to the Special Issue Sustainable Bio-Based Nanomaterials for Various Biological Applications)
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12 pages, 3660 KiB  
Article
Sustainable Environmental-Based ZnO Nanoparticles Derived from Pisonia grandis for Future Biological and Environmental Applications
by Thiyakarajan Sutharappa Kaliyamoorthy, Vijayakumar Subramaniyan, Sangeetha Renganathan, Vidhya Elavarasan, Jagatheesvaran Ravi, Praseetha Prabhakaran Kala, Prathipkumar Subramaniyan and Sekar Vijayakumar
Sustainability 2022, 14(24), 17009; https://doi.org/10.3390/su142417009 - 19 Dec 2022
Cited by 8 | Viewed by 2032
Abstract
The bio-synthesis of zinc oxide nanoparticles (ZnO NPs) using aqueous leaf extract of Pisonia grandis is discussed in this work as an effective ecologically beneficial and straightforward method. This strategy intends to increase ZnO nanoparticle usage in the biomedical and environmental sectors, while [...] Read more.
The bio-synthesis of zinc oxide nanoparticles (ZnO NPs) using aqueous leaf extract of Pisonia grandis is discussed in this work as an effective ecologically beneficial and straightforward method. This strategy intends to increase ZnO nanoparticle usage in the biomedical and environmental sectors, while reducing the particle of hazardous chemicals in nanoparticle synthesis. In the current study, bio-augmented zinc oxide nanomaterials (ZnO-NPs) were fabricated from Pisonia grandis aqueous leaf extracts. Different methods were used to analyze the ZnO-nanoparticles including X-ray diffraction (XRD), Fourier Transforms Infrared (FT-IR), Ultraviolet (UV) spectroscopy, and Field Emission Scanning Electron Microscopy (FE-SEM) with EDX. The synthesized nanoparticles as spheres were verified by FE-SEM analysis; XRD measurements showed that the particle flakes had an average size of 30.32 nm and were very pure. FT-IR analysis was used to validate the functional moieties in charge of capping and stabilizing ZnO nanoparticles. The antimicrobial, cytotoxic, and photodegradation properties of synthesized nanoparticles were assessed using well diffusion, MTT, and UV visible irradiation techniques. The bio-fabricated nanoparticles were proven to be outstanding cytotoxic and antimicrobial nanomaterials. As a result of the employment of biosynthesized ZnO nanoparticles as photocatalytic agents, 89.2% of the methylene blue dye was degraded in 140 min. ZnO nanoparticles produced from P. grandis can serve as promising substrates in biomedicine and applications of environmental relevance due to their eco-friendliness, nontoxic behavior, and cytocompatibility. Full article
(This article belongs to the Special Issue Sustainable Bio-Based Nanomaterials for Various Biological Applications)
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13 pages, 4462 KiB  
Article
Bio-Mediated Zinc Oxide Nanoparticles through Tea Residue: Ecosynthesis, Characterizations, and Biological Efficiencies
by Tamil Elakkiya Mathizhagan, Vijayakumar Subramaniyan, Sangeetha Renganathan, Vidhya Elavarasan, Prathipkumar Subramaniyan and Sekar Vijayakumar
Sustainability 2022, 14(23), 15572; https://doi.org/10.3390/su142315572 - 23 Nov 2022
Cited by 10 | Viewed by 1876
Abstract
Recent advances in nanotechnology have placed a major emphasis on environmentally friendly processes that encourage sustainable growth by using moderate reaction conditions and non-toxic precursors. In the present study, a simple, inventive, and affordable green technique was applied to generate bio-augmented ZnO nanoparticles [...] Read more.
Recent advances in nanotechnology have placed a major emphasis on environmentally friendly processes that encourage sustainable growth by using moderate reaction conditions and non-toxic precursors. In the present study, a simple, inventive, and affordable green technique was applied to generate bio-augmented ZnO nanoparticles using an aqueous extract of tea residue as a reducing and stabilizing component. Numerous methods, including UV-Vis, XRD, FT-IR, FE-SEM with EDAX and TEM were used to analyze ZnO nanoparticles that were generated. The antimicrobial capabilities of biomediated ZnO nanoparticles against pathogenic organisms were examined using an agar well method. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT assay) and flow cytometry analysis was utilized to explore cytotoxic effects and apoptosis, and methylene blue dye was used to examine photocatalytic activity. The ZnO nanoparticles demonstrated considerable anticancer activity in human lung cancer cells (A549) as well as highly effective antibacterial activity against several different microbial pathogens. Furthermore, the greatest degradation percentage of methylene blue obtained was found to be 86% after 140 min. Therefore, it is concluded that the chosen nanoparticle combination enhanced antimicrobial, anticancer and photocatalytic activities. The combination may represent a useful tool for removing dye pollution from wastewater and, ideally, be used in the pharmaceutical sector to combat lung cancer. Full article
(This article belongs to the Special Issue Sustainable Bio-Based Nanomaterials for Various Biological Applications)
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Review

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22 pages, 3394 KiB  
Review
Bio-Enzyme Hybrid with Nanomaterials: A Potential Cargo as Sustainable Biocatalyst
by Wan Yuen Tan, Subash C. B. Gopinath, Periasamy Anbu, Ahmad Radi Wan Yaakub, Sreeramanan Subramaniam, Yeng Chen and Sreenivasan Sasidharan
Sustainability 2023, 15(9), 7511; https://doi.org/10.3390/su15097511 - 4 May 2023
Cited by 8 | Viewed by 3282
Abstract
With advancements in bionanotechnology, the field of nanobiocatalysts has undergone rapid growth and revolutionized various nanomaterials as novel and fascinating nanocarriers for enzyme immobilization. Nanotubes, nanofibers, nanopores, nanoparticles, and nanocomposites have been successfully developed and used as nanocarriers. The construction of robust nanobiocatalysts [...] Read more.
With advancements in bionanotechnology, the field of nanobiocatalysts has undergone rapid growth and revolutionized various nanomaterials as novel and fascinating nanocarriers for enzyme immobilization. Nanotubes, nanofibers, nanopores, nanoparticles, and nanocomposites have been successfully developed and used as nanocarriers. The construction of robust nanobiocatalysts by combining enzymes and nanocarriers using various enzyme immobilization techniques is gaining incredible attention because of their extraordinary catalytic performance, high stability, and ease of reusability under different physical and chemical conditions. Creating appropriate surface chemistry for nanomaterials promotes their downstream applications. This review discusses enzyme immobilization on nanocarriers and highlights the techniques, properties, preparations, and applications of nanoimmobilized enzymes. Full article
(This article belongs to the Special Issue Sustainable Bio-Based Nanomaterials for Various Biological Applications)
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Other

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9 pages, 5577 KiB  
Brief Report
Biofabricated Aluminium Oxide Nanoparticles Derived from Citrus aurantium L.: Antimicrobial, Anti-Proliferation, and Photocatalytic Efficiencies
by Punitha Nagarajan, Vijayakumar Subramaniyan, Vidhya Elavarasan, Nilavukkarasi Mohandoss, Prathipkumar Subramaniyan and Sekar Vijayakumar
Sustainability 2023, 15(2), 1743; https://doi.org/10.3390/su15021743 - 16 Jan 2023
Cited by 9 | Viewed by 3272
Abstract
A current strategy in material science and nanotechnology is the creation of green metal oxide nanoparticles. Citrus aurantium peel extract was used to create aluminium oxide nanoparticles (Al2O3 NPs) in an efficient, affordable, environmentally friendly, and simple manner. Various characterisation [...] Read more.
A current strategy in material science and nanotechnology is the creation of green metal oxide nanoparticles. Citrus aurantium peel extract was used to create aluminium oxide nanoparticles (Al2O3 NPs) in an efficient, affordable, environmentally friendly, and simple manner. Various characterisation methods such as UV-vis spectrophotometer (UV), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and field emission scanning electron microscopy (FE-SEM) were utilised to assess the morphology of Al2O3 NPs. The elemental composition was performed by EDX analysis. Using the well diffusion method, Al2O3 NPs’ antimicrobial properties were used against pathogenic organisms. The antiproliferation efficacy of a neuronal cell line was investigated using the MTT assay. The photocatalytic activities were studied against methylene blue dye. In this study, Al2O3 NPs were found to have an average crystallite size of 28 nm in the XRD, an absorption peak at 322 nm in the UV spectrum, and functional groups from 406 to 432 in the FT-IR spectrum, which were ascribed to the stretching of aluminium oxide. Antimicrobial efficiencies were observed against Pseudomonas aeruginosa [36 ± 2.12], Staphylococcus aureus [35 ± 1.23], Staphylococcus epidermis [27 ± 0.06], Klebsiella pneumonia [25 ± 1.65], Candida albicans [28 ± 1.06], and Aspergillus niger [27 ± 2.23], as well as the cell proliferation of a PC 12 cell line (54.09 at 31.2 μg/mL). Furthermore, photocatalytic degradation of methylene blue dye decreased up to 89.1 percent after 150 min. The current investigation concluded that biosynthesised Al2O3 NPs exhibit feasible antimicrobial, anti-proliferative, and photocatalytic behaviours. Full article
(This article belongs to the Special Issue Sustainable Bio-Based Nanomaterials for Various Biological Applications)
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