Symmetry/Asymmetry in Molecular Medicinal Chemistry
A special issue of Symmetry (ISSN 2073-8994). This special issue belongs to the section "Chemistry: Symmetry/Asymmetry".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 912
Special Issue Editors
Interests: medicinal chemistry; drug design; organic synthesis; heterocyclic compounds; biological activity; SAR; ADME; lipophilicity; PCA; K-means clustering; peptide chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: chemically synthetized and/or modified antimicrobial molecules; antimicrobial potential testing; antimicrobial resistance; molecular docking; molecular descriptors
Special Issues, Collections and Topics in MDPI journals
Interests: chemical development (synthesis, structural analysis) of new heterocyclic molecules with antimicrobial; anticancer; anti-inflammatory; antioxidant potential
Interests: synthetic organic chemistry; medicinal and pharmaceutical chemistry; anti-inflammatory synthesis of medicinal compounds; organic synthesis; heterocyclic chemistry; synthetic medicinal chemistry; heterocyclic compounds synthesis
Special Issue Information
Dear Colleagues,
The world contains a vast array of natural products, many of which have also become indispensable drugs for humans. However, many of these pharmaceutically active substances exist in two possible configurations (a phenomenon known as chirality) and are only effective in one of them, akin to mirror images of each other (enantiomers), and may even be harmful in the other form.
The concept of chirality is the pillar of asymmetric synthesis, which is one of most intriguing areas in medicinal chemistry.
Since the tragedy of racemic thalidomide usage, chiral separation and enantioselective synthesis have become prominent areas of research in chemistry. Most drugs on the market today have chiral compounds in them, and the number of enantiomerically pure drugs currently on the market is on the rise. At the same time, a full chirality analysis, including determination of absolute configuration and enantiomeric excess, becomes essential in pharmaceutical industry for quality control and in every step in the development of new drugs.
This Special Issue entitled “Symmetry/Asymmetry in Molecular Medicinal Chemistry” seeks original research papers and high-quality reviews in the fields of medicinal chemistry and symmetry/asymmetry of bioactive compounds.
Dr. Ioana Ionuț
Dr. Gabriel Marc
Dr. Anca Stana
Dr. Cătălin Araniciu
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Symmetry is an international peer-reviewed open access monthly journal published by MDPI.
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