New Advances in Asymmetric Organocatalysis
A special issue of Symmetry (ISSN 2073-8994). This special issue belongs to the section "Chemistry: Symmetry/Asymmetry".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 3521
Special Issue Editors
Interests: organic chemistry; domino reactions; organocatalysis; asymmetric synthesis; biomimetic chemistry; biomarkers development; radical stress
Interests: organic synthesis; natural products; supramolecular chemistry in water media; bioactive compounds; photoactive organic compounds
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Special Issue Information
Dear Colleagues,
The synthesis of enantioenriched organic molecules plays a pivotal role in organic chemistry, having essential applications in the preparation of pharmaceutically relevant compounds. Indeed, enantiomers of bioactive compounds often possess very different pharmacological effects, and thus, the synthesis of enantiopure drugs and/or their intermediates remains a central topic for synthetic organic chemists.
Organocatalysis has proven to be an efficient and environmentally friendly alternative to the most common organometallic synthetic methodologies for the achievement of molecular structures in an enantioselective fashion. Certainly, several advantages associated with the employment of small organic molecules as catalysts have been identified: (1) various and simultaneous activation modes for substrates and reagents are possible; (2) these catalysts are, in general, cheaper, more readily available, and easier to synthesize than enzymes or metal complexes; (3) frequently, inert atmosphere and dry solvents are not necessary due to the high stability of the organocatalysts; and (4) organocatalysts can be successfully combined with metal catalysts to promote the cooperative activation of different substrates. Further, several research groups have focused on the development of innovative organocatalytic domino/one-pot reaction sequences to achieve highly diastereo- and enantioenriched complex molecular scaffolds, providing atom and step-economical synthetic methodologies.
The aim of this Special Issue is to advance the knowledge on organocatalytic methodologies for the asymmetric synthesis of enantioenriched organic compounds, involving also synergistic/cooperative catalysis and domino/one-pot reaction sequences. Moreover, studies on the use of organocatalytic methodologies in the total synthesis of potentially bioactive compounds are of interest.
As Guest Editors it is our pleasure to invite you to contribute research and review articles on asymmetric organocatalysis to this Special Issue.
Submit your paper and select the Journal “Symmetry” and the Special Issue “New Frontiers in Asymmetric Organocatalysis” via: MDPI submission system. Our papers will be published on a rolling basis and we will be pleased to receive your submission once you have finished it.
Dr. Fabrizio Vetica
Prof. Dr. Jesús F. Arteaga
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Symmetry is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- asymmetric organocatalysis
- enantioselective synthesis
- domino/one-pot reaction sequences
- covalent and non-covalent organocatalysis
- enantioselectivity
- cooperative catalysis
- bioactive compounds
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