Novel Air Pollutants and Respiratory Disorders: Epidemiological Evidence and Biological Mechanism

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Air Pollution and Health".

Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 2864

Special Issue Editors


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Guest Editor
School of Public Health, Guangzhou Medical University, Guangzhou 511436, China
Interests: environmental pollutants; respiratory disorders; noncoding RNA
Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Interests: ambient air pollution; silica particles; lung fibrosis; lung inflammation; lung function
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Institute for Chemical Carcinogenesis, Guangzhou Medical University, Guangzhou 511436, China
Interests: environmental toxicology; chemical carcinogenesis; noncoding RNA

Special Issue Information

Dear Colleagues,

Exposure to air pollutants can trigger or exacerbate a variety of lung diseases, leading to hospitalization, cancer, and even premature death. Existing studies have primarily concentrated on common air pollutants; however, as novel pollutants continue to emerge, there is an urgent need to focus on novel air pollutants, elucidating their respiratory effects and underlying mechanisms. For this Special Issue, we welcome the submission of original research and review articles on, but not limited to, the following topics:

  • Evaluating inhalation exposure to novel air pollutants
  • Links between novel air pollutants and lung diseases
  • Toxicology and mechanisms of inhaled toxicants

Prof. Dr. Yun Zhou
Dr. Jixuan Ma
Prof. Dr. Yiguo Jiang
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • novel air pollutants
  • inhaled toxicants
  • epidemiology
  • toxicology
  • mechanism
  • lung diseases
  • respiratory health

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Published Papers (1 paper)

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Review

17 pages, 503 KiB  
Review
Respiratory Toxicology of Graphene-Based Nanomaterials: A Review
by Chunxue Kong, Junwen Chen, Ping Li, Yukang Wu, Guowei Zhang, Bimin Sang, Rui Li, Yuqin Shi, Xiuqing Cui and Ting Zhou
Toxics 2024, 12(1), 82; https://doi.org/10.3390/toxics12010082 - 18 Jan 2024
Cited by 5 | Viewed by 1955
Abstract
Graphene-based nanomaterials (GBNs) consist of a single or few layers of graphene sheets or modified graphene including pristine graphene, graphene nanosheets (GNS), graphene oxide (GO), reduced graphene oxide (rGO), as well as graphene modified with various functional groups or chemicals (e.g., hydroxyl, carboxyl, [...] Read more.
Graphene-based nanomaterials (GBNs) consist of a single or few layers of graphene sheets or modified graphene including pristine graphene, graphene nanosheets (GNS), graphene oxide (GO), reduced graphene oxide (rGO), as well as graphene modified with various functional groups or chemicals (e.g., hydroxyl, carboxyl, and polyethylene glycol), which are frequently used in industrial and biomedical applications owing to their exceptional physicochemical properties. Given the widespread production and extensive application of GBNs, they can be disseminated in a wide range of environmental mediums, such as air, water, food, and soil. GBNs can enter the human body through various routes such as inhalation, ingestion, dermal penetration, injection, and implantation in biomedical applications, and the majority of GBNs tend to accumulate in the respiratory system. GBNs inhaled and substantially deposited in the human respiratory tract may impair lung defenses and clearance, resulting in the formation of granulomas and pulmonary fibrosis. However, the specific toxicity of the respiratory system caused by different GBNs, their influencing factors, and the underlying mechanisms remain relatively scarce. This review summarizes recent advances in the exposure, metabolism, toxicity and potential mechanisms, current limitations, and future perspectives of various GBNs in the respiratory system. Full article
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