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Journals
Toxins
Special Issues
Toxins in Dermatology
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Toxins in Dermatology

A special issue of Toxins (ISSN 2072-6651).

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 7980

Special Issue Editor

Dr. Mohamad Goldust

E-Mail Website
Guest Editor
Department of Dermatology, Yale School of Medicine, Yale University, New Haven, CT, USA
Interests: dermatology; artificial intelligence
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Skin is the protective covering of the body. It is designed to defend against invading pathogens. Many dermatological problems have been associated with toxins in the environment. The role of many toxins has not yet been fully understood in the pathophysiology of cutaneous diseases. In this context, the editors of Toxins have set up a Special Issue dedicated to various toxins and their effects in skin diseases.

Dr. Mohamad Goldust
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • skin toxins
  • skin harm
  • toxic agents in dermatology

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Published Papers (1 paper)

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Research

11 pages, 1381 KiB  
Article
Botulinum Toxin Type A for Treatment of Forehead Hyperhidrosis: Multicenter Clinical Experience and Review from Literature
by Anna Campanati, Emanuela Martina, Stamatis Gregoriou, George Kontochristopoulos, Matteo Paolinelli, Federico Diotallevi, Giulia Radi, Ivan Bobyr, Barbara Marconi, Giulio Gualdi, Paolo Amerio and Annamaria Offidani
Toxins 2022, 14(6), 372; https://doi.org/10.3390/toxins14060372 - 27 May 2022
Cited by 5 | Viewed by 7112
Abstract
Among the forms of idiopathic hyperhidrosis, those involving the forehead have the greatest impact on patients’ quality of life, as symptoms are not very controllable and are difficult to mask for patients. Although the local injection therapy with Incobotulinum toxin type A (IncoBTX-A [...] Read more.
Among the forms of idiopathic hyperhidrosis, those involving the forehead have the greatest impact on patients’ quality of life, as symptoms are not very controllable and are difficult to mask for patients. Although the local injection therapy with Incobotulinum toxin type A (IncoBTX-A therapy) can be considered a rational treatment, data from the literature describing both efficacy and safety of the treatment over the long term are poor. The aim of this report is to describe the single-center experience of five patients seeking treatment, for forehead hyperhidrosis with IncoBTX-A. To evaluate the benefits, safety profile and duration of anhidrosis, patients were treated following a standardized procedure and then followed until clinical relapse. The amount of sweating was measured by gravimetric testing, the extension of hyperhidrosis area was measured through Minor’s iodine starch test, and response to the treatment was evaluated using the Hyperhidrosis Disease Severity Scale (HDSS) and the Dermatology Life Quality Index (DLQI). In all treated patients, a significant anhidrotic effect was observed 4 weeks after the treatment and lasted for approximately 36 weeks. The reduction in sweat production was associated with significant amelioration of symptoms and quality of life for all treated patients. No serious side effects occurred; one patient complained of a mild transient bilateral ptosis. Although further wider studies are required, our preliminary results seem to encourage the use of IncoBTX-A in forehead hyperhidrosis. Full article
(This article belongs to the Special Issue Toxins in Dermatology)
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