SARS-CoV-2 Serology for the Rapid Diagnosis of COVID-19
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "COVID-19 Vaccines and Vaccination".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2248
Special Issue Editor
Special Issue Information
Dear Colleagues,
Serology tests, or antibody tests, use a variety of techniques to detect antibodies from the blood, revealing whether a person has been exposed to a particular pathogen by looking at their immune response.
Serological tests also vary according to the viral antigens measured. Spike proteins (S) and nucleocapsid proteins (N) are the viral antigens used to detect antibodies for SARS-CoV-2, with the intended use to identify whether an individual was recently or previously infected by the virus. These serology tests can be broadly categorized by their readout platforms used to detect SARS-CoV-2 antibodies: enzyme immunoassay, high-throughput; enzyme immunoassay, medium-throughput; lateral flow assay; and total neutralizing antibodies.
A reliable serology test to rapidly quantify neutralizing antibody levels in a high-throughput manner is essential for diagnosis, vaccine development, and antiviral development—especially once a minimal threshold of nAb has been defined for disease prevention in the near future. Even in a postvaccination era, serology tests will remain critical for studying both individuals’ and the community's protective immunity to safeguard public health around the world. Based on your extensive knowledge and experience, we invite you to contribute with an original report, original observation, or review to highlight the new trends in serology tests for COVID-19.
Dr. Jesus Alberto Silvas
Guest Editor
Manuscript Submission Information
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Keywords
- COVID-19
- SARS-CoV-2
- serology test
- antibody test
- diagnostic test
- vaccination
- immunization
- antibody response
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