Vaccination, Public Health and Epidemiology

A special issue of Vaccines (ISSN 2076-393X).

Deadline for manuscript submissions: 30 June 2025 | Viewed by 1967

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Guest Editor
Director Donald Price Center Department of Global Health College of Public Health University of South Florida, Tampa, FL 33620, USA
Interests: vaccine; vaccinology; epidemiology; infectious diseases; public health; emerging infectious diseases; tropical neglected diseases
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Special Issue Information

Dear Colleagues,

This Special Issue focuses on the current state of vaccinology as applied to the epidemiology control of infectious diseases, as well as the philosophies, findings, and dynamics of vaccine-preventable diseases and current immunization strategies in the context of public health interventions. In addition to the currently available vaccines, this Special Issue will review new vaccines for emerging and re-emerging diseases, as well as vaccines for neglected tropical diseases. Furthermore, it will address the process of vaccine development, vaccine platforms, and vaccine trials. Papers addressing public health strategies applied to vaccine-preventable disease control are also invited.

Dr. Ricardo Izurieta
Guest Editor

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Keywords

  • vaccine
  • vaccinology
  • epidemiology
  • infectious diseases
  • public health
  • emerging infectious diseases
  • tropical neglected diseases

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Published Papers (2 papers)

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Research

15 pages, 311 KiB  
Article
Mpox Vaccine Hesitancy Among Brazilian Men Who Have Sex with Men: A National Cross-Sectional Study
by Guilherme Reis de Santana Santos, Caíque Jordan Nunes Ribeiro, José Flávio Cerqueira dos Santos Júnior, Valdemar Silva Almeida, Rita de Cassia Dias Nascimento, Nilo Manoel Pereira Vieira Barreto, Anderson Reis de Sousa, Márcio Bezerra-Santos, Lariane Angel Cepas, Ana Paula Morais Fernandes, Isabel Amélia Costa Mendes, Aires Garcia dos Santos Júnior, Maria Luisa Pereira Maronesi and Álvaro Francisco Lopes de Sousa
Vaccines 2024, 12(11), 1229; https://doi.org/10.3390/vaccines12111229 - 29 Oct 2024
Viewed by 855
Abstract
Background: Mpox is a viral zoonosis that has gained increased attention due to a global outbreak in 2022, significantly impacting men who have sex with men (MSM). Vaccination for this disease poses a public health challenge; because it carries a strong stigma, there [...] Read more.
Background: Mpox is a viral zoonosis that has gained increased attention due to a global outbreak in 2022, significantly impacting men who have sex with men (MSM). Vaccination for this disease poses a public health challenge; because it carries a strong stigma, there may be greater hesitancy in vulnerable groups. Objectives: This study aimed to determine the prevalence and factors associated with Mpox vaccine hesitancy among Brazilian MSM. Methods: A cross-sectional study was conducted between September and December 2022 using an online survey targeted at MSM. Recruitment was carried out through social media and dating apps. The sample consisted of 1449 participants and the analysis involved bivariate logistic regression. Results: The prevalence of Mpox vaccine hesitancy was 7.57%. The significant factors associated with hesitancy were primarily related to sexual practices and attitudes towards Mpox exposure and diagnosis, such as not using “glory holes” (aOR: 19.82; 95% CI: 1.60–245.69), reluctance to undergo pre- and post-exposure testing for Mpox (aOR: 9.54; 95% CI: 5.52–16.48), and not knowing close contacts diagnosed with Mpox (aOR: 4.09; 95% CI: 1.72–9.73). Participants who would not take precautions after diagnosis (aOR: 3.00; 95% CI: 1.27–7.07) and those who would not disclose their serological status (aOR: 1.93; 95% CI: 1.13–3.30) also showed a higher likelihood of vaccine hesitancy. Conclusion: Public health strategies should address these factors to expand knowledge about vaccination barriers, plan educational campaigns with targeted messaging for the MSM population, and provide inclusive healthcare environments to increase vaccine acceptance and reduce Mpox transmission in vulnerable groups. Full article
(This article belongs to the Special Issue Vaccination, Public Health and Epidemiology)
10 pages, 811 KiB  
Article
Pertussis Outbreak During 2023 in Gipuzkoa, North Spain
by José María Marimón, Milagrosa Montes, Nahikari Vizuete, Lorea Alvarez Guerrico, Adrian Hugo Aginagalde, Alba Mir-Cros, Juan José González-López and Diego Vicente
Vaccines 2024, 12(10), 1192; https://doi.org/10.3390/vaccines12101192 - 18 Oct 2024
Viewed by 739
Abstract
Background: Pertussis has re-emerged in many countries despite the wide use of vaccines for over 60 years. During 2023, we observed an increase in the incidence of pertussis in Gipuzkoa, north of Spain (with a population of 657,140 inhabitants), mainly affecting children between [...] Read more.
Background: Pertussis has re-emerged in many countries despite the wide use of vaccines for over 60 years. During 2023, we observed an increase in the incidence of pertussis in Gipuzkoa, north of Spain (with a population of 657,140 inhabitants), mainly affecting children between 11 and 15 years of age. Methods: This study included all confirmed cases diagnosed by PCR in nasopharyngeal swab samples. The genome of seven isolates collected in 2023 was sequenced. Results: Between 2018 and 2023, 884 cases of whooping cough were diagnosed. Pertussis incidence (in cases per 100,000 inhabitants) decreased from 36.7 in 2018 to no cases in 2021, increasing again to 56.8 in 2023. In 2023, the age group of 11–15 years old had the highest incidence rate of 409.3. Only 2 of the 56 children < 6 years old required hospitalization, and there were no deaths. The seven isolates collected in 2023 showed the same BPagST-4 (ptxA1/ptxP3/prn2/fim2-1/fim3-1 allelic combination), with all of them expressing the pertactin antigen. Conclusions: Immunity waning after the last dose of vaccination at 6 years old, together with the lack of circulation of Bordetella pertussis during the COVID-19 pandemic, were probably the main reasons for the high increase in the incidence of pertussis in Gipuzkoa in 2023. Full article
(This article belongs to the Special Issue Vaccination, Public Health and Epidemiology)
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