Correction: Funk et al. Criticality of Surface Characteristics of Intravenous Iron-Carbohydrate Nanoparticle Complexes: Implications for Pharmacokinetics and Pharmacodynamics. Int. J. Mol. Sci. 2022, 23, 2140
Product | Molecular Weight (kDa) | Particle Size (nm)[39] | Zeta Potential (mV)[39] | Crystalline Structure | Reduction Potential (mV) °[25] | Reduction Kinetics k(Θ) × 103 (min−1) Θ = 0.1/0.5/0.8[25] | Blocking Temperature (K) [25,40] |
Iron sucrose | 34–60 [17,41] 42–44 [25] 252 [42] 140 [39] | 8.3 (PDI 0.192) | pH 7.43: −26.20 pH 11.03 *: −28.15 | 2-line ferrihydrite [39] Ferrihydrite and lepidocrocite [41] Akageneite [33] 2-line ferrihydrite-like [40] No clear identification [25] | −494 | 107/89/117 § | 55 |
Sodium ferric gluconate | 289–440 [18] 37.5 [9] 200 [42] 164 [39] | 8.6 (PDI 0.244) | pH 7.4: −29.70 pH 8.36 *: −29.10 | 2-line ferrihydrite ([39] Ferrihydrite and lepidocrocite [41] Akaganeite [33] | nd | nd | nd |
Iron dextran | 165 [20] 165 [39] | 12.2 (PDI 0.149) | pH 6.4 *: −15.30 pH 7.31: −17.25 | Akageneite [39,41] | nd | nd | nd |
Ferric derisomaltose | 155[22] 63–69 [25] 150 [39] | 9.9 (PDI 0.182) | pH 6.3 *: −22.0 pH 7.35: −21.05 | Akaganeite [25,39,41] | −338/−508 | 21/41/63 | 56 |
Ferric carboxymaltose | ≈ 150 [24] 145–155 [25] 233 [39] | 23.1 (PDI 0.07) | pH 5.36: 3.68 pH 7.26: −8.52 | Akaganeite [25,39,41] | −333 | 18/35/55 | 114 |
Ferumoxytol | 750 [26] 172–188 [25] 731 [42] 276 [39] | 23.6 (PDI 0.143) | pH 6.6: −43.20 pH 7.36: −30.55 | Magnetite/Maghemite [39] Magnetite [41] Maghemite [25] | −245/−768 | 36/67/98 | 73 |
Reference
- Funk, F.; Flühmann, B.; Barton, A.E. Criticality of surface characteristics of intravenous iron-carbohydrate nanoparticle complexes: Implications for pharmacokinetics and pharmacodynamics. Int. J. Mol. Sci. 2022, 23, 2140. [Google Scholar] [CrossRef] [PubMed]
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Funk, F.; Flühmann, B.; Barton, A.E. Correction: Funk et al. Criticality of Surface Characteristics of Intravenous Iron-Carbohydrate Nanoparticle Complexes: Implications for Pharmacokinetics and Pharmacodynamics. Int. J. Mol. Sci. 2022, 23, 2140. Int. J. Mol. Sci. 2022, 23, 10230. https://doi.org/10.3390/ijms231810230
Funk F, Flühmann B, Barton AE. Correction: Funk et al. Criticality of Surface Characteristics of Intravenous Iron-Carbohydrate Nanoparticle Complexes: Implications for Pharmacokinetics and Pharmacodynamics. Int. J. Mol. Sci. 2022, 23, 2140. International Journal of Molecular Sciences. 2022; 23(18):10230. https://doi.org/10.3390/ijms231810230
Chicago/Turabian StyleFunk, Felix, Beat Flühmann, and Amy E. Barton. 2022. "Correction: Funk et al. Criticality of Surface Characteristics of Intravenous Iron-Carbohydrate Nanoparticle Complexes: Implications for Pharmacokinetics and Pharmacodynamics. Int. J. Mol. Sci. 2022, 23, 2140" International Journal of Molecular Sciences 23, no. 18: 10230. https://doi.org/10.3390/ijms231810230
APA StyleFunk, F., Flühmann, B., & Barton, A. E. (2022). Correction: Funk et al. Criticality of Surface Characteristics of Intravenous Iron-Carbohydrate Nanoparticle Complexes: Implications for Pharmacokinetics and Pharmacodynamics. Int. J. Mol. Sci. 2022, 23, 2140. International Journal of Molecular Sciences, 23(18), 10230. https://doi.org/10.3390/ijms231810230